» Editorial: The voluminous axon as an organizing principle for traumatic brain injury therapeutics: novel molecular, metabolic, and circuit strategies
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
No abstract available

» Wallerian degeneration as a therapeutic target in traumatic brain injury
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review Diffuse or traumatic axonal injury is one of the principal pathologies encountered in traumatic brain injury (TBI) and the resulting axonal loss, disconnection, and brain atrophy contribute significantly to clinical mor...

» Transglutaminases, neuronal cell death and neural repair: implications for traumatic brain injury and therapeutics
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review Traumatic brain injury (TBI) is one of the leading causes of death in the developed world. Despite advances at the bedside, pharmacological interventions have yet to be successful likely because of the need for a better...

» Autonomic dysfunction following mild traumatic brain injury
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review Between 1.6 and 3.6 million concussions, or mild traumatic brain injuries (mTBI), occur each year, nearly half of which go unreported and untreated. Despite the high incidence, practitioners currently lack both objectiv...

» Exercise factors as potential mediators of cognitive rehabilitation following traumatic brain injury
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review To summarize what is known about how exercise mediates cognitive rehabilitation post traumatic brain injury (TBI). Recent findings TBI is a devastating condition that leads to cognitive, motor and social deficits with s...

» Sugar as a therapeutic target for the cognitive restoration following traumatic brain injury
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review This review aims to discuss examples of changes in glucose (sugar) metabolism after traumatic brain injury (TBI). It will attempt to provide an understanding of what changes in glucose metabolism mean for the injured br...

» Novel synaptic plasticity enhancer drug to augment functional recovery with rehabilitation
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review Stroke is a devastating illness which severely attenuates quality of life because of paralysis. Despite recent advances in therapies during acute phase such as thrombolytic therapy, clinical option to intervene the proc...

» Enhancing rehabilitation and functional recovery after brain and spinal cord trauma with electrical neuromodulation
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review This review discusses recent advances in the rehabilitation of motor deficits after traumatic brain injury (TBI) and spinal cord injury (SCI) using neuromodulatory techniques. Recent findings Neurorehabilitation is curr...

» Novel sensory paradigms for neuromodulation in disorders of consciousness in traumatic brain injury
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review Traumatic brain injury (TBI) represents a major cause of mortality and disability worldwide. In cases of severe TBI, disorders of consciousness (DoC) can occur and therapeutic options for these conditions are few and of...

» Applications of artificial intelligence in neuro-oncology
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review To discuss recent applications of artificial intelligence within the field of neuro-oncology and highlight emerging challenges in integrating artificial intelligence within clinical practice. Recent findings In the fiel...

» New metabolic imaging tools in neuro-oncology
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review The current treatment of gliomas dovetails results of decades-old clinical trials with modern trends in chemotherapy. Molecular characterization now plays a pivotal role, and IDH mutations are key characteristics and th...

» Targeting DNA repair in gliomas
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review Gliomas represent a disparate group of malignancies with varying clinical outcomes despite a tremendous amount of time, effort, and resources dedicated to their management and understanding. The most aggressive entity, ...

» Progress in rare central nervous system tumors
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review Although all primary central nervous system (CNS) tumors are rare, certain tumor types each represent less than 2% of the total and an annual incidence of about 1000 patients or less. Most of them are disproportionally ...

» Complications associated with immunotherapy for brain metastases
01/12/19 06:00 from Current Opinion in Neurology - Current Issue
Purpose of review Median survival after the diagnosis of brain metastases has historically been on the order of months. With the recent development of immune checkpoint inhibitors, intracranial activity and durable responses have been ob...

» Neurology: Challenges, opportunities, and the way forward
18/11/19 20:45 from Neurology current issue
The profession of neurology has come a long way over the years. In 1664, Thomas Willis in his textbook Cerebral Anatomy described the different structures in the brain and coined the word "neurology"—a branch of medicine concerned ...

» What's happening in Neurology(R)
18/11/19 20:45 from Neurology current issue

» What's happening in Neurology(R) Genetics
18/11/19 20:45 from Neurology current issue

» Editors' note: Brain death, the determination of brain death, and member guidance for brain death accommodation requests: AAN position statement
18/11/19 20:45 from Neurology current issue
On behalf of the Brain Death Working Group, Dr. Russell and colleagues have provided medical professionals and the public with formal guidance as to the definition and determination of brain death. This AAN position statement answers man...

» Reader response: Brain death, the determination of brain death, and member guidance for brain death accommodation requests: AAN position statement
18/11/19 20:45 from Neurology current issue
I read with interest the AAN position statement on brain death, the determination of brain death, and member guidance for brain death accommodation requests. 1

» Author response: Brain death, the determination of brain death, and member guidance for brain death accommodation requests: AAN position statement
18/11/19 20:45 from Neurology current issue
On behalf of the Brain Death Working Group, I thank Drs. Sethi, Machado, and Robbins for their comments and for their support of the recently published AAN position statement on brain death. 1

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