Voxel-based dysconnectomic brain morphometry with compute...
OBJECTIVE: Alzheimer's disease (AD) is a major health concern for aging adults with Down syndrome (DS), but conventional diagnostic techniques are less relia...

Identifying dementia in Down syndrome with the Severe Imp...
CONCLUSIONS: Results suggest that the SIB, BPT and DLD are able to reasonably discriminate consensus dementia diagnoses in individuals with DS, supporting th...

The direct health care cost to Medicare of Down syndrome ...
CONCLUSION: DS adults with dementia have higher health care costs than DS adults without dementia and adults with AD. Understanding costs and complex health ...

Copper accumulation in the brain of Down syndrome model m...
Down syndrome caused by triplication of human chromosome 21 (HSA21) is the most frequent aneuploidy, resulting in mental retardation, intellectual disability...

Plasma neurofilament light chain: A potential prognostic ...
People with Down syndrome (DS) are at high risk of developing Alzheimer disease (AD) with aging. The diagnosis and treatment trials are hampered by a lack of...