Microneedle electrodes for electromyography
Wednesday, September 10, 2025

Surface electromyography (sEMG) is the measurement of the electrical activity of muscle and is extensively used in fundamental research and across many applications in health and sport. Conventional surface electrode technology can suffer from poor signal quality, particularly when used outside t... .. read more..

Multiphysics modelling of the impact of skin deformation and strain on micron...
Sunday, December 22, 2024

Microneedle patches (MNs) hold enormous potential to facilitate the minimally-invasive delivery of drugs and vaccines transdermally. However, the micro-mechanics of skin deformation significantly influence the permeation of therapeutics through the skin. Previous studies often fail to appreciate ... .. read more..

A needle that softens on intravenous insertion
Friday, December 22, 2023

No abstract .. read more..

Mechanical characterisation of commercial artificial skin models
Sunday, September 17, 2023

Understanding of the mechanical properties of skin is crucial in evaluating the performance of skin-interfacing medical devices. Artificial skin models (ASMs) have rapidly gained attention as they are able to overcome the challenges in ethically sourcing consistent and representative ex vivo anim... .. read more..

Metallic Microneedles for Transdermal Drug Delivery: Applications, Fabricatio...
Saturday, January 21, 2023

Current procedures for transdermal drug delivery (TDD) have associated limitations including poor administration of nucleic acid, small or large drug molecules, pain and stress for needle phobic people. A painless micro-sized device capable of delivering drugs easily and efficiently, eliminating ... .. read more..

A therapeutic convection-enhanced macroencapsulation device for enhancing β c...
Friday, September 10, 2021

Islet transplantation for type 1 diabetes treatment has been limited by the need for lifelong immunosuppression regimens. This challenge has prompted the development of macroencapsulation devices (MEDs) to immunoprotect the transplanted islets. While promising, conventional MEDs are faced with in... .. read more..

Insights into the mechanics of solid conical microneedle array insertion into...
Tuesday, September 7, 2021

In order to develop optimum microneedle designs, researchers must first develop robust, repeatable and adaptable test methods which are representative of in vivo conditions. However, there is a lack of experimental tools which can accurately comparatively interrogate functional microneedle penetr... .. read more..

Additive Manufacturing of Multi-Scale Porous Soft Tissue Implants That Encour...
Thursday, June 24, 2021

Medical devices, such as silicone-based prostheses designed for soft tissue implantation, often induce a suboptimal foreign-body response which results in a hardened avascular fibrotic capsule around the device, often leading to patient discomfort or implant failure. Here, it is proposed that add... .. read more..