A needle that softens on intravenous insertion
Friday, December 22, 2023
No abstract .. read more..
Mechanical characterisation of commercial artificial skin models
Sunday, September 17, 2023
Understanding of the mechanical properties of skin is crucial in evaluating the performance of skin-interfacing medical devices. Artificial skin models (ASMs) have rapidly gained attention as they are able to overcome the challenges in ethically sourcing consistent and representative ex vivo anim... .. read more..
Metallic Microneedles for Transdermal Drug Delivery: Applications, Fabricatio...
Saturday, January 21, 2023
Current procedures for transdermal drug delivery (TDD) have associated limitations including poor administration of nucleic acid, small or large drug molecules, pain and stress for needle phobic people. A painless micro-sized device capable of delivering drugs easily and efficiently, eliminating ... .. read more..
A therapeutic convection-enhanced macroencapsulation device for enhancing β c...
Friday, September 10, 2021
Islet transplantation for type 1 diabetes treatment has been limited by the need for lifelong immunosuppression regimens. This challenge has prompted the development of macroencapsulation devices (MEDs) to immunoprotect the transplanted islets. While promising, conventional MEDs are faced with in... .. read more..
Insights into the mechanics of solid conical microneedle array insertion into...
Tuesday, September 7, 2021
In order to develop optimum microneedle designs, researchers must first develop robust, repeatable and adaptable test methods which are representative of in vivo conditions. However, there is a lack of experimental tools which can accurately comparatively interrogate functional microneedle penetr... .. read more..
Additive Manufacturing of Multi-Scale Porous Soft Tissue Implants That Encour...
Thursday, June 24, 2021
Medical devices, such as silicone-based prostheses designed for soft tissue implantation, often induce a suboptimal foreign-body response which results in a hardened avascular fibrotic capsule around the device, often leading to patient discomfort or implant failure. Here, it is proposed that add... .. read more..
In silico design of additively manufacturable composite synthetic va...
Tuesday, March 16, 2021
Benchtop testing of endovascular medical devices under accurately simulated physiological conditions is a critical part of device evaluation prior to clinical assessment. Currently, glass, acrylic and silicone vascular models are predominantly used as anatomical simulator test beds for in vitro t... .. read more..
A Radial Clutch Needle for Facile and Safe Tissue Compartment Access
Monday, October 12, 2020
Efficient and safe access to targeted therapeutic sites is a universal challenge in minimally invasive medical intervention. Percutaneous and transluminal needle insertion is often performed blindly and requires significant user skill and experience to avoid complications associated with the dama... .. read more..