» One pill post stroke . . . and other research
14/05/26 09:46 from Latest headlines from BMJ
Combination pills after intracerebral haemorrhageAlthough single pill combination antihypertensives are available in the UK, prescribing each medication as an individual tablet is the norm. A large multicentre trial explored the use of a...

» Endovascular Therapy for Medium-Vessel Occlusion Stroke — Narrowing the Target Population
13/05/26 09:00 from Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
New England Journal of Medicine, Volume 394, Issue 19, Page 1955-1957, May 14/21, 2026.

» Systemic Cardiovascular Factors and Outcomes in Dural Arteriovenous Fistulas: Insights From the CONDOR Registry
11/05/26 09:01 from
Stroke, Ahead of Print. BACKGROUND:Hemorrhagic risk in dural arteriovenous fistulas (dAVFs) is largely determined by venous anatomy, but the contribution of systemic cardiovascular factors and their medical therapy remains poorly defined...

» Social and Environmental Determinants of Stroke Functional Outcome and Strategies to Reduce Inequities: A Scientific Statement From the American Heart Association
11/05/26 09:00 from
Stroke, Ahead of Print. Stroke is a leading cause of death and disability worldwide, and the recovery process is significantly influenced by a multitude of factors beyond immediate medical treatment. Social and environmental determinants...

» Safety of Rapid Local Ischemic Postconditioning After Thrombectomy in Acute Stroke: A Dose-Finding Trial (RAPID SAVE)
11/05/26 09:00 from
Stroke, Ahead of Print. BACKGROUND:Rapid local ischemic postconditioning may protect the brain after acute ischemic stroke, but its safety and optimal dosing in successfully reperfused patients after mechanical thrombectomy remain undefi...

» [Comment] TAPIS: a positive trial in a defined phenotype
08/05/26 09:52 from The Lancet
Clinical trials in stroke balance a few tensions including efficacy against safety, biology against clinical proof, and broad answers against a disease that is not really one disease. Antiplatelet therapy after intravenous thrombolysis i...

» [Articles] Ticagrelor with aspirin dual antiplatelet therapy combined with intravenous thrombolysis in patients with ischaemic stroke in China (TAPIS): a multicentre, double-blind, randomised controlled trial
08/05/26 09:52 from The Lancet
Among patients treated with intravenous thrombolysis for moderate ischaemic stroke, initiation of oral DAPT within 6 h of onset improved the likelihood of excellent functional outcomes at 90 days. Although no significant between-group di...

» Polygenic Risk Identifies Older Adults Who May Benefit From Aspirin for the Primary Prevention of Ischemic Stroke
08/05/26 09:00 from
Stroke, Ahead of Print. BACKGROUND:Low-dose aspirin is no longer recommended for routine primary prevention in older adults due to bleeding risks outweighing vascular benefits. We hypothesized that an integrative polygenic score (iPGS) c...

» Longitudinal Degeneration of Microstructural and Structural Connectivity Patterns Following Stroke
08/05/26 09:00 from
Stroke, Ahead of Print. BACKGROUND:Stroke causes neurological impairment through local plasticity mechanisms, such as synaptic sprouting, and large-scale network reorganization. Although poststroke Wallerian degeneration is well establis...

» Transcranial Direct Current Stimulation for Stroke Motor Recovery What the TRANSPORT2 Trial Taught Us
08/05/26 09:00 from
Stroke, Ahead of Print. Over the past 2 decades, transcranial direct current stimulation has attracted substantial interest as an adjunctive strategy to enhance poststroke motor recovery. In addition to its potential neuromodulatory effe...

» Minimal Sufficient Balance Randomization and Site-Specific Covariate and Group Size Imbalance in Multicenter Acute Stroke Trials
08/05/26 09:00 from
Stroke, Ahead of Print. BACKGROUND:Preservation of treatment allocation randomness, achievement of treatment group size balance, and balance on prognostic baseline covariates are desirable properties of optimal randomization schemes. Pre...

» Sex-Based Efficacy of Endovascular Thrombectomy Techniques in LVO Stroke: A Multicenter Registry Analysis
08/05/26 09:00 from
Stroke, Ahead of Print. BACKGROUND:Sex differences in stroke cause, vessel anatomy, and thrombus composition are well established, yet whether these factors influence the efficacy of specific endovascular thrombectomy (EVT) techniques re...

» Redefining the Cerebral Ischemic Core-Penumbra-Oligemia Continuum
08/05/26 09:00 from
Stroke, Ahead of Print. During acute ischemic stroke, cerebral tissue undergoes different stages of ischemic damage and evolves towards irreversible injury at a varying pace depending on local perfusion and metabolic factors. This comple...

» Sarcopenia, Grip Strength, Walking Pace, and New-Onset Stroke Risk: A UK Biobank Study
08/05/26 03:11 from
Stroke, Ahead of Print. BACKGROUND:Novel stroke risk factors have received widespread attention. This study examined the association between sarcopenia status, grip strength, and walking pace with incident stroke (any stroke, ischemic st...

» Intracranial and Peripheral Inflammatory Biomarkers Predict Futile Recanalization after Endovascular Treatment
07/05/26 09:01 from
Stroke, Ahead of Print. BACKGROUND:Futile recanalization (absence of functional independence despite successful endovascular treatment [EVT]) remains a limitation in the treatment of large vessel occlusion stroke. Inflammation has emerge...

» Expression of Concern for: Ethanol and Normobaric Oxygen Novel Approach in Modulating Pyruvate Dehydrogenase Complex After Severe Transient and Permanent Ischemic Stroke
07/05/26 09:01 from
Stroke, Ahead of Print.

» Peripheral Electrical Nerve Stimulation Rescues Spatial Memory Deficits in Vascular Cognitive Impairment Rats by Engaging a Central Cholinergic Circuit
07/05/26 09:00 from
Stroke, Ahead of Print. BACKGROUND:Vascular cognitive impairment (VCI) is a prevalent and heterogeneous condition, both clinically and pathophysiologically, that still lacks approved treatment. Peripheral electrical nerve stimulation (PE...

» Retraction of: Synergetic Neuroprotection of Normobaric Oxygenation and Ethanol in Ischemic Stroke Through Improved Oxidative Mechanism
07/05/26 09:00 from
Stroke, Ahead of Print.

» National Evaluation of Racial, Ethnic, and Insurance-Based Disparities in Interhospital Transfer of Patients With Ischemic Stroke
07/05/26 09:00 from
Stroke, Ahead of Print. BACKGROUND:Disparities in interfacility transfer of patients with acute ischemic stroke have been identified at the regional level, but a national analysis has not been conducted. This study aims to evaluate patie...

» Predictors of Hematoma Expansion and Response to Andexanet in Patients With Intracerebral Hemorrhage: Secondary Analyses of the ANNEXA-I Randomized Clinical Trial
07/05/26 09:00 from
Stroke, Ahead of Print. BACKGROUND:Andexanet improves hemostatic efficacy in FXa (factor Xa) inhibitor–associated intracranial hemorrhage but carries a risk of thrombotic events. These secondary analyses of the ANNEXA-I trial examined de...