» A pragmatic and scalable strategy using mobile technology to promote sustained lifestyle changes to prevent type 2 diabetes in India and the UK: a randomised controlled trial
01/03/20 00:00 from Latest Results for Diabetologia
Abstract Aims/hypothesis This randomised controlled trial was performed in India and the UK in people with prediabetes to study whether mobile phone short message service (SMS) text messages can be used to motivate and educate people to ...

» Incidence and relative risk of renal replacement therapy in people with and without diabetes between 2002 and 2016 in a German region
01/03/20 00:00 from Latest Results for Diabetologia
Abstract Aims/hypothesis Data on trends of end-stage renal disease among people with diabetes are lacking. We analysed the incidence of end-stage renal disease, defined as renal replacement therapy, among people with and without diabetes...

» Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised controlled clinical trial
01/03/20 00:00 from Latest Results for Diabetologia
Abstract Aims/hypothesis Intra-abdominal or visceral obesity is associated with insulin resistance and an increased risk for cardiovascular disease. This study aimed to compare the effects of semaglutide 1.0 mg and canagliflozin 300 mg o...

» Duration of Hybrid Closed-Loop Insulin Therapy to Achieve Representative Glycemic Outcomes in Adults With Type 1 Diabetes
20/02/20 19:55 from Diabetes Care Journal current issue

» Randomized Controlled Trial of Mobile Closed-Loop Control
20/02/20 19:55 from Diabetes Care Journal current issue
OBJECTIVE Assess the efficacy of inControl AP, a mobile closed-loop control (CLC) system. RESEARCH DESIGN AND METHODS This protocol, NCT02985866 , is a 3-month parallel-group, multicenter, randomized unblinded trial designed to compare m...

» A Multinational, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Efficacy of Cyclical Topical Wound Oxygen (TWO2) Therapy in the Treatment of Chronic Diabetic Foot Ulcers: The TWO2 Study
20/02/20 19:55 from Diabetes Care Journal current issue
OBJECTIVE Topical oxygen has been used for the treatment of chronic wounds for more than 50 years. Its effectiveness remains disputed due to the limited number of robust high-quality investigations. The aim of this study was to assess th...

» Confirming the Bidirectional Nature of the Association Between Severe Hypoglycemic and Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL
20/02/20 19:55 from Diabetes Care Journal current issue
OBJECTIVE We sought to confirm a bidirectional association between severe hypoglycemic events (SHEs) and cardiovascular (CV) event risk and to characterize individuals at dual risk. RESEARCH DESIGN AND METHODS In a post hoc analysis of 1...

» Nutrient-Induced Metabolic Stress, Adaptation, Detoxification, and Toxicity in the Pancreatic {beta}-Cell
20/02/20 19:55 from Diabetes Journal current issue
Paraphrasing the Swiss physician and father of toxicology Paracelsus (1493–1541) on chemical agents used as therapeutics, "the dose makes the poison," it is now realized that this aptly applies to the calorigenic nutrients. The cas...

» Understanding Metabolic Memory: A Tale of Two Studies
20/02/20 19:55 from Diabetes Journal current issue
The results of the Diabetes Control and Complications Trial (DCCT) have given rise to much encouragement in the battle to stave off the complications of type 1 diabetes, showing dramatic declines in the development of severe retinopathy,...

» The Novel Adipokine Gremlin 1 Antagonizes Insulin Action and Is Increased in Type 2 Diabetes and NAFLD/NASH
20/02/20 19:55 from Diabetes Journal current issue
The BMP2/4 antagonist and novel adipokine Gremlin 1 is highly expressed in human adipose cells and increased in hypertrophic obesity. As a secreted antagonist, it inhibits the effect of BMP2/4 on adipose precursor cell commitment/differe...

» Inhibition of NFAT Signaling Restores Microvascular Endothelial Function in Diabetic Mice
20/02/20 19:55 from Diabetes Journal current issue
Central to the development of diabetic macro- and microvascular disease is endothelial dysfunction, which appears well before any clinical sign but, importantly, is potentially reversible. We previously demonstrated that hyperglycemia ac...

» Targeting the NADPH Oxidase-4 and Liver X Receptor Pathway Preserves Schwann Cell Integrity in Diabetic Mice
20/02/20 19:55 from Diabetes Journal current issue
Diabetes triggers peripheral nerve alterations at a structural and functional level, collectively referred to as diabetic peripheral neuropathy (DPN). This work highlights the role of the liver X receptor (LXR) signaling pathway and the ...

» Predictors and consequences of declining insulin therapy by individuals with type 2 diabetes
20/02/20 19:36 from Diabetic Medicine
Diabetic Medicine, EarlyView.

» Psychosocial aspects and contributions of behavioural science to medication‐taking for adults with type 2 diabetes
15/02/20 07:35 from Diabetic Medicine
Diabetic Medicine, Volume 37, Issue 3, Page 427-435, March 2020.

» How 25 years of psychosocial research has contributed to a better understanding of the links between depression and diabetes
15/02/20 07:35 from Diabetic Medicine
Diabetic Medicine, Volume 37, Issue 3, Page 383-392, March 2020.

» Trends in diabetes self‐management education: where are we coming from and where are we going? A narrative review
15/02/20 07:35 from Diabetic Medicine
Diabetic Medicine, Volume 37, Issue 3, Page 436-447, March 2020.

» How has psycho‐behavioural research advanced our understanding of hypoglycaemia in type 1 diabetes?
15/02/20 07:35 from Diabetic Medicine
Diabetic Medicine, Volume 37, Issue 3, Page 409-417, March 2020.

» A preclinical assessment to repurpose drugs to target type 1 diabetes‐associated type B coxsackieviruses
14/02/20 17:35 from Diabetic Medicine
Diabetic Medicine, EarlyView.

» What are the characteristics of the best type 1 diabetes patient education programmes (from diagnosis to long‐term care), do they improve outcomes and what is required to make them more effective?
08/02/20 14:36 from Diabetic Medicine
Diabetic Medicine, Volume 0, Issue ja, -Not available-.

» Systematic review and meta‐analysis of randomized controlled trials of psychological interventions to improve glycaemic control in children and adults with type 1 diabetes
06/02/20 02:36 from Diabetic Medicine
Diabetic Medicine, Volume 0, Issue ja, -Not available-.

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