• Mature dendritic cell vesicles enhance influenza vaccine effectiveness
    Wednesday, July 2, 2025 from News-Medical.Net Vaccine News Feed
    Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant that enhances the body's immune response, according to a study...
  • As mosquito season peaks, officials brace for new normal of dengue cases
    Wednesday, July 2, 2025 from News-Medical.Net Vaccine News Feed
    As summer ushers in peak mosquito season, health and vector control officials are bracing for the possibility of another year of historic rates of dengue.
  • How underreporting masks the real impact of RSV in older populations
    Tuesday, July 1, 2025 from News-Medical.Net Vaccine News Feed
    Research shows RSV leads to high hospitalization rates in adults, emphasizing the importance of enhanced surveillance and diagnostic measures in healthcare.
  • This virus infects millions—and we just discovered its secret weapon
    Monday, June 30, 2025 from Vaccines News -- ScienceDaily
    Scientists have discovered a stealthy mechanism that cytomegalovirus (CMV)—the leading infectious cause of birth defects in the U.S.—uses to infiltrate blood vessel cells while evading immune detection. The virus forms a hidden protein...
  • Shingles and RSV vaccines with AS01 adjuvant reduce dementia risk
    Monday, June 30, 2025 from News-Medical.Net Vaccine News Feed
    Researchers found that older adults who received AS01-adjuvanted shingles or RSV vaccines had a significantly lower risk of developing dementia within 18 months compared to flu vaccine recipients. The protective effect is likely linked...
  • GATE complex discovery sheds light on CMV's evasion of immune defenses
    Monday, June 30, 2025 from News-Medical.Net Vaccine News Feed
    New research from the University of Pittsburgh School of Medicine and La Jolla Institute for Immunology, published today in Nature Microbiology, reveals an opportunity for developing a therapy against cytomegalovirus (CMV), the leading...
  • A Texas boy needed protection from measles. The vaccine cost $1,400.
    Monday, June 30, 2025 from News-Medical.Net Vaccine News Feed
    In the early days of the West Texas measles outbreak, Thang Nguyen eyed the rising number of cases and worried. His 4-year-old son was at risk because he had received only the first of the vaccine's two doses.
  • Kennedy’s vaccine advisers sow doubts as scientists protest US pivot on shots
    Friday, June 27, 2025 from News-Medical.Net Vaccine News Feed
    As fired and retired scientists rallied outside in the Atlanta heat, an advisory panel that Robert F. Kennedy Jr. handpicked to replace experts he'd fired earlier met inside the Centers for Disease Control and Prevention's headquarters...
  • Parkinson’s may begin decades earlier — and your immune system might know first
    Friday, June 27, 2025 from Immune System News -- ScienceDaily
    Misbehaving T cells light up long before Parkinson’s symptoms show, zeroing in on vulnerable brain proteins. Their early surge could double as an alarm bell and a target for stop-it-early treatments.
  • New U.S. poll shows strong backing for routine childhood vaccines
    Thursday, June 26, 2025 from News-Medical.Net Vaccine News Feed
    In the midst of a multi-state measles outbreak, a new poll by Harvard T.H. Chan School of Public Health and the de Beaumont Foundation finds that most U.S. adults (79%) say parents should be required to have children vaccinated against...
  • Hot tubs outperform saunas in boosting blood flow and immune power
    Thursday, June 26, 2025 from Immune System News -- ScienceDaily
    Hot tubs don't just feel great, they may actually outperform saunas when it comes to health perks. A study found that soaking in hot water raises core body temperature more than dry or infrared saunas, triggering stronger heart, blood...
  • Updated COVID-19 vaccines found effective against severe illness
    Wednesday, June 25, 2025 from News-Medical.Net Vaccine News Feed
    A new multi-state study led by the Centers for Disease Control and Prevention's (CDC) VISION Network – including Regenstrief Institute – has provided the most comprehensive assessment to date of the effectiveness of 2023-2024 COVID-19...
  • Missing gut bacteria in US babies triples allergy and eczema risk
    Wednesday, June 25, 2025 from News-Medical.Net Vaccine News Feed
    US infants lacking Bifidobacterium in their gut microbiome face significant changes in microbial composition, metabolic function, and immune-related health risks. This large, nationally representative study links early-life...
  • How brain cells meant to help may be making depression worse
    Tuesday, June 24, 2025 from Immune System News -- ScienceDaily
    Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously overshadowed by microglia—as major players in...
  • COVID-19 protein triggers immune attacks on healthy cells — but a common drug can stop it
    Tuesday, June 24, 2025 from Vaccines News -- ScienceDaily
    Scientists have uncovered a stealthy tactic used by the SARS-CoV-2 virus: one of its proteins can leap from infected cells to healthy ones, effectively tricking the immune system into attacking the body’s own tissues.
  • One shot to stop HIV: MIT's bold vaccine breakthrough
    Thursday, June 19, 2025 from Vaccines News -- ScienceDaily
    Researchers from MIT and Scripps have unveiled a promising new HIV vaccine approach that generates a powerful immune response with just one dose. By combining two immune-boosting adjuvants alum and SMNP the vaccine lingers in lymph nodes...
  • New mRNA vaccine is more effective and less costly to develop
    Tuesday, June 3, 2025 from Vaccines News -- ScienceDaily
    A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a new study.
  • Large-scale immunity profiling grants insights into flu virus evolution
    Tuesday, June 3, 2025 from Vaccines News -- ScienceDaily
    A new study shows how person-to-person variation in antibody immunity plays a key role in shaping which influenza (flu) strains dominate in a population.
  • Preventing chronic inflammation from turning into cancer
    Monday, June 2, 2025 from Immune System News -- ScienceDaily
    Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors coincide,...
  • Innovative immunotherapy shows promise against aggressive T cell cancers
    Friday, May 30, 2025 from Immune System News -- ScienceDaily
    An international clinical trial shows an innovative CAR-T cell immunotherapy is promising against aggressive T cell cancers and has manageable side effects.
  • HIV vaccine study uncovers powerful new antibody target
    Tuesday, May 27, 2025 from Vaccines News -- ScienceDaily
    In the long battle to create an effective HIV vaccine, scientists have made a major leap forward. A new study shows that a series of vaccines can coax the immune system to produce powerful antibodies capable of blocking a wide range of...
  • Engineered bacteria can deliver antiviral therapies, vaccines
    Wednesday, May 21, 2025 from Vaccines News -- ScienceDaily
    New research demonstrates how specially engineered bacteria taken orally can operate as a delivery system for vaccines and antiviral therapies.
  • 'Barcodes' written into our DNA reveal how blood ages
    Wednesday, May 21, 2025 from Immune System News -- ScienceDaily
    A study explains how age reshapes the blood system. In both humans and mice, a few stem cells out-compete their neighbors and gradually take over blood production. The loss of diversity results in a blood system that has a preference for...
  • Why some viral infections appear to trigger autoimmune disease
    Tuesday, May 20, 2025 from Immune System News -- ScienceDaily
    By studying Chikungunya virus, scientists shed light on how immune responses to viral infections may lead to persistent symptoms of autoimmune disease.
  • Maintaining balance in the immune system
    Monday, May 19, 2025 from Immune System News -- ScienceDaily
    Researchers have published the first description of the role of the ZFP36 family of RNA binding proteins in regulatory T cells (Tregs). Tregs are key to maintaining balance in the immune system and essential to preventing autoimmune...
  • Two HIV vaccine trials show proof of concept for pathway to broadly neutralizing antibodies
    Thursday, May 15, 2025 from Vaccines News -- ScienceDaily
    A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional approaches haven't worked -- largely because...
  • Particles carrying multiple vaccine doses could reduce the need for follow-up shots
    Thursday, May 15, 2025 from Vaccines News -- ScienceDaily
    New polymer microparticles can be used to deliver vaccines at different times. The work could lead to childhood vaccines given just once, eliminating the need for booster doses.
  • Protein switch turns anti-viral immune response on and off
    Thursday, May 15, 2025 from Immune System News -- ScienceDaily
    An international research team has discovered a critical protein that acts as a 'switch' regulating immune responses to viruses.
  • New study offers insights into designing safe, effective nasal vaccines
    Wednesday, May 14, 2025 from Vaccines News -- ScienceDaily
    Most vaccines -- and boosters -- are injected directly into muscle tissue, usually in the upper arm, to kickstart the body's immune system in the fight against disease. But for respiratory diseases like COVID-19, it can be important to...
  • Yellow fever vaccination: How strong immune responses are triggered
    Wednesday, May 14, 2025 from Vaccines News -- ScienceDaily
    Researchers show how specific immune cells are activated by the vaccine -- an important starting point for the development of new vaccines.
  • CAR-T cell therapy for cancer causes 'brain fog,' study shows
    Monday, May 12, 2025 from Immune System News -- ScienceDaily
    Cancer treatment with a cell-based immunotherapy causes mild cognitive impairment, a Stanford Medicine team found. They also identified compounds that could treat it.
  • Novel, needle-free, live-attenuated influenza vaccines with broad protection against human and avian virus subtypes
    Friday, May 9, 2025 from Vaccines News -- ScienceDaily
    A research team has achieved a significant breakthrough in developing broadly protective, live-attenuated influenza vaccines (LAIV). These innovative LAIV platforms offer potential to develop universal influenza vaccines that induce a...
  • Evaluating the safety and efficacy of a smallpox vaccine for preventing mpox
    Thursday, May 8, 2025 from Vaccines News -- ScienceDaily
    The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated vaccinia virus strain originally...
  • Building vaccines for future versions of a virus
    Thursday, May 8, 2025 from Vaccines News -- ScienceDaily
    AI model EVE-Vax provides clues about how a virus may evolve and the immune response it could provoke.
  • Enhanced CAR T cell therapy offers new strategy for lymphoma
    Wednesday, May 7, 2025 from Immune System News -- ScienceDaily
    A phase I study of a next-generation CAR T cell therapy showed a 52 percent complete remission rate for patients with relapsed/refractory lymphoma.
  • Vaccines of the future: Harnessing the immune system for long-lasting protection
    Wednesday, May 7, 2025 from Immune System News -- ScienceDaily
    Scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines for viruses and enhanced cancer therapies....
  • Shingles vaccine lowers the risk of heart disease for up to eight years
    Monday, May 5, 2025 from Vaccines News -- ScienceDaily
    People who are given a vaccine for shingles have a 23% lower risk of cardiovascular events, including stroke, heart failure, and coronary heart disease, according to a recent study of more than a million people. The protective effect of...
  • Explaining the link between 'good' gut bacteria and rheumatoid arthritis
    Thursday, May 1, 2025 from Immune System News -- ScienceDaily
    After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of 'good' microbes in the gut is linked to rheumatoid arthritis and, potentially,...
  • Left or right arm? New research reveals why vaccination site matters for immune response
    Monday, April 28, 2025 from Vaccines News -- ScienceDaily
    Scientists have uncovered why vaccines can elicit a stronger immune response if they are administered in the same arm.
  • A drug dismantles a metabolic barrier to anti-tumor immunity
    Monday, April 28, 2025 from Immune System News -- ScienceDaily
    A new study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses.
  • Immune cells drive congenital paralysis disease
    Friday, April 25, 2025 from Immune System News -- ScienceDaily
    Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the brain appears to play a major role by...
  • B cells found to be crucial for long-term vaccine protection, new study shows
    Wednesday, April 23, 2025 from Vaccines News -- ScienceDaily
    Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 T cells, teaching them how to mount...
  • Empowering antibodies to better activate the immune system
    Tuesday, April 22, 2025 from Immune System News -- ScienceDaily
    Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these immune proteins can do more than that: They also activate other components of the immune system, which then go to...
  • Americans don't think bird flu is a threat, study suggests
    Friday, April 18, 2025 from Vaccines News -- ScienceDaily
    A team led by researchers say public ignorance and apathy towards bird flu (highly pathogenic avian influenza, or HPAI) could pose a serious obstacle to containing the virus and preventing a larger-scale public health crisis.
  • Experimental bird flu vaccine excels in animal models
    Thursday, April 17, 2025 from Vaccines News -- ScienceDaily
    A vaccine under development has demonstrated complete protection in mice against a deadly variant of the virus that causes bird flu. The work focuses on the H5N1 variant known as 2.3.4.4b, which has caused widespread outbreaks in wild...
  • Nasal spray H5N1 avian influenza vaccine developed
    Tuesday, April 8, 2025 from Vaccines News -- ScienceDaily
    Scientists have pioneered an influenza virus vector-based nasal spray vaccine platform and developed a nasal spray H5N1 avian influenza vaccine. During the early COVID-19 pandemic, this platform enabled the rapid development of a nasal...
  • Viral 'backbone' underlies variation in rotavirus vaccine effectiveness
    Tuesday, April 8, 2025 from Vaccines News -- ScienceDaily
    Researchers have shown that differences in the entire rotavirus genome -- not just its two surface proteins -- affect how well vaccines work, helping to explain why some strains are more likely to infect vaccinated individuals.
  • New research boosts future whooping cough vaccines
    Friday, April 4, 2025 from Vaccines News -- ScienceDaily
    New research could aid in improving whooping cough vaccines to once again push this disease toward eradication by targeting two key weaknesses in the infection.
  • An antiviral chewing gum to reduce influenza and herpes simplex virus transmission
    Friday, April 4, 2025 from Vaccines News -- ScienceDaily
    Low vaccination rates for influenza viruses and the lack of an HSV vaccine underscore the need for a new approach to reduce viral transmission. Researchers have now used a clinical-grade antiviral chewing gum to substantially reduce...
  • New vaccine concept tackles harmful bacteria in the intestine
    Thursday, April 3, 2025 from Vaccines News -- ScienceDaily
    In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning point in the antibiotics crisis.
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