» Variation in duration of repeat prescriptions: a primary care cohort study in England
26/06/25 23:05 from British Journal of General Practice recent issues
BackgroundMany patients receive repeat prescriptions for routine medications used to treat chronic conditions. Doctors typically issue repeat prescriptions with durations ranging from 28 to 84 days. There is currently no national guidanc...

» Impact of an SMS intervention to support type 2 diabetes self-management: DiabeText clinical trial
26/06/25 23:05 from British Journal of General Practice recent issues
BackgroundComplications arising from uncontrolled type 2 diabetes mellitus (T2DM) pose a significant burden on individuals’ wellbeing and healthcare resources. Digital interventions may play a key role in mitigating such complications by...

» Potential interactions between direct oral anticoagulants and atorvastatin/simvastatin: a cohort and case-crossover study
26/06/25 23:05 from British Journal of General Practice recent issues
BackgroundDirect oral anticoagulants (DOACs) are commonly co-prescribed with statins. Although biologically plausible, whether there is a drug interaction between DOACs and atorvastatin/simvastatin is unclear.AimTo investigate the associ...

» Effectiveness of low-dose amitriptyline and mirtazapine in patients with insomnia disorder and sleep maintenance problems: a randomised, double-blind, placebo-controlled trial in general practice (DREAMING)
26/06/25 23:05 from British Journal of General Practice recent issues
BackgroundLow-dose amitriptyline and mirtazapine are widely prescribed off-label for insomnia disorder. However, evidence of their effectiveness from placebo-controlled studies is lacking.AimTo assess the effectiveness of low-dose mirtaz...

» Antidepressants and risk of postural hypotension: a self-controlled case series study in UK primary care
26/06/25 23:05 from British Journal of General Practice recent issues
BackgroundAntidepressants are associated with postural hypotension (PH), but it is not typically recognised as a common adverse effect. PH is linked with serious complications in older adults, for example, falls, stroke, and cognitive de...

» Patient and family engagement interventions in primary care patient safety: systematic review and meta-analysis of randomised controlled trials
26/06/25 23:05 from British Journal of General Practice recent issues
BackgroundEngaging patients and families has been promoted as a key strategy for improving patient safety of health systems. However, evidence remains scarce on the effectiveness of this approach in primary care.AimTo assess the combined...

» Development and internal validation of a diagnostic prediction model for life-threatening events in callers with shortness of breath: a cross-sectional study in out-of-hours primary care
26/06/25 23:05 from British Journal of General Practice recent issues
BackgroundShortness of breath often prompts calls to out-of-hours primary care and is the prime reason for home visits by GPs. However, a diagnostic prediction model in this setting is lacking.AimTo develop and internally validate a mode...