Consensus for experimental design in electromyography (CEDE) project: Checkli...
Thursday, March 28, 2024
The diversity in electromyography (EMG) techniques and their reporting present significant challenges across multiple disciplines in research and clinical practice, where EMG is commonly used. To address these challenges and augment the reproducibility and interpretation of studies using EMG, the... .. read more..
Language-Independent Acoustic Biomarkers for Quantifying Speech Impairment in...
Tuesday, March 26, 2024
CONCLUSION: The results support the application of acoustic features to objectively quantify speech impairment and disease severity in HD in multilanguage studies. .. read more..
Assessment of Fitbit Charge 4 for sleep stage and heart rate monitoring again...
Thursday, March 7, 2024
CONCLUSIONS: Results suggest the potential for long-term monitoring of sleep patterns using wrist-worn wearable devices as part of symptom management in HD. .. read more..
Electroencephalographic β-band oscillations in the sensorimotor network refle...
Thursday, January 18, 2024
CONCLUSIONS: β-Band spectral power in the sensorimotor cortex reflects clinically evaluated motor impairment in ALS. This technology merits further investigation as a biomarker of progressive functional disability. .. read more..
Impact of Network Topology on Neural Synchrony in a Model of the Subthalamic ...
Monday, December 25, 2023
Synchronous neural oscillations within the beta frequency range are observed across the parkinsonian basal ganglia network, including within the subthalamic nucleus (STN) - globus pallidus (GPe) subcircuit. The emergence of pathological synchrony in Parkinson's disease is often attributed to chan... .. read more..
Multivariable closed-loop control of deep brain stimulation for Parkinson's d...
Thursday, September 21, 2023
Objective. Closed-loop deep brain stimulation (DBS) methods for Parkinson's disease (PD) to-date modulate either stimulation amplitude or frequency to control a single biomarker. While good performance has been demonstrated for symptoms that are correlated with the chosen biomarker, suboptimal re... .. read more..
Micromotion Derived Fluid Shear Stress Mediates Peri-Electrode Gliosis throug...
Sunday, July 30, 2023
The development of bioelectronic neural implant technologies has advanced significantly over the past 5 years, particularly in brain-machine interfaces and electronic medicine. However, neuroelectrode-based therapies require invasive neurosurgery and can subject neural tissues to micromotion-indu... .. read more..
Waist-What? Can a single sensor positioned at the waist detect parameters of ...
Thursday, June 8, 2023
One of the problems facing an ageing population is functional decline associated with reduced levels of physical activity (PA). Traditionally researcher or clinician input is necessary to capture parameters of gait or PA. Enabling older adults to monitor their activity independently could raise t... .. read more..
On-Off and Proportional Closed-Loop Adaptive Deep Brain Stimulation Reduces M...
Sunday, May 28, 2023
CONCLUSIONS: Adaptive DBS, using both on-off and proportional control schemes, is as effective as conventional DBS in reducing motor symptoms of PD in parkinsonian rats. Both aDBS algorithms yield substantial reductions in stimulation power. These findings support using hemiparkinsonian rats as a... .. read more..
Cortico-muscular coherence in primary lateral sclerosis reveals abnormal cort...
Thursday, May 4, 2023
Primary lateral sclerosis (PLS) is a slowly progressing disorder, which is characterized primarily by the degeneration of upper motor neurons (UMNs) in the primary motor area (M1). It is not yet clear how the function of sensorimotor networks beyond M1 are affected by PLS. The aim of this study w... .. read more..
Consensus for experimental design in electromyography (CEDE) project: Single ...
Monday, December 26, 2022
The analysis of single motor unit (SMU) activity provides the foundation from which information about the neural strategies underlying the control of muscle force can be identified, due to the one-to-one association between the action potentials generated by an alpha motor neuron and those receiv... .. read more..
Effects of Contralateral Deep Brain Stimulation and Levodopa on Subthalamic N...
Tuesday, December 13, 2022
CONCLUSIONS: The results provide new insights into the effects of DBS and levodopa on STN LFP PAC and oscillatory activity on the side contralateral to stimulation. These may have important implications in understanding mechanisms underlying motor improvements with DBS, including changes on both ... .. read more..
Comparison of Acoustic Voice Features Derived From Mobile Devices and Studio ...
Tuesday, November 15, 2022
CONCLUSIONS: Mobile devices provided good agreement with state of the art, high-quality microphones during structured speech tasks for features derived from frequency components of the audio recordings. Caution should be taken when estimating HNR, shimmer and its variants from recordings made wit... .. read more..
Prediction of low pulse oxygen saturation in COVID-19 using remote monitoring...
Tuesday, November 8, 2022
CONCLUSION: Results indicate that SpO(2) alerts (SpO(2) < 94 %) on a given day can be predicted using SpO(2) and heart rate data captured on the two preceding days via remote monitoring. The methods presented may help early identification of patients with COVID-19 at risk of clinical deterioratio... .. read more..
Correction to: Computational Model of the Effect of Mitochondrial Dysfunction...
Tuesday, October 11, 2022
No abstract .. read more..