» Trauma-associated acute kidney injury
01/12/19 06:00 from Current Opinion in Critical Care - Current Issue
Purpose of review A summary of recent research into the epidemiology, cause, management and outcomes of trauma-associated acute kidney injury (AKI). There is an increasing focus on subtypes of AKI to better target clinical management and...

» Emergent airway management of the critically ill patient: current opinion in critical care
01/12/19 06:00 from Current Opinion in Critical Care - Current Issue
Purpose of review To describe techniques to facilitate safe intubation in critically ill patients. Recent findings Despite advances in the treatment of critically ill patients, endotracheal intubation remains a high-risk procedure associ...

» Emergency bedside ultrasound-benefits as well as caution: Part 2: Echocardiography
01/12/19 06:00 from Current Opinion in Critical Care - Current Issue
Purpose of review Critical care echocardiography (CCE) has become an important component of general critical care ultrasonography, and a current review of its performance is presented. Recent findings Basic CCE should be performed as a g...

» Initial management of severe burn injury
01/12/19 06:00 from Current Opinion in Critical Care - Current Issue
Purpose of review Patients with severe burn injuries pose significant challenges for the intensivist. Though average burn sizes have decreased over time, severe burn injuries involving greater than 20% of the total body surface area stil...

» Sudden unresponsive patient with normal vital signs: what is going on?
01/12/19 06:00 from Current Opinion in Critical Care - Current Issue
Purpose of review To summarize the differential diagnosis and diagnostic approach of sudden unresponsiveness with normal vital signs in various settings, including the ICU. Recent findings Sudden unresponsiveness may be either transient ...

» Ultrasound in the surgical ICU: uses, abuses, and pitfalls
01/12/19 06:00 from Current Opinion in Critical Care - Current Issue
Purpose of review Point-of-care ultrasound (POCUS) has become an integral component of daily care in the surgical ICU. There have been many novel advancements in the past two decades, too numerous to count. Many are of critical importanc...

» Caring for the surgical patient with limited ICU resources
01/12/19 06:00 from Current Opinion in Critical Care - Current Issue
Purpose of review The current review aims to discuss the management of surgical patients in an ICU in countries where resources are limited. Recent findings ICU beds in low-income and middle-income countries (LMICs) are limited and also ...

» Which Multicenter Randomized Controlled Trials in Critical Care Medicine Have Shown Reduced Mortality? A Systematic Review
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: To determine which multicenter randomized controlled trials in critically ill patients have shown that the study intervention was associated with a statistically significant reduction in mortality. Our analysis provides an up...

» Promoting Family Engagement in the ICU: Experience From a National Collaborative of 63 ICUs*
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: As part of an improvement program targeting ICU, a national collaborative was launched to help hospitals implement patient- and family-centered care engagement initiatives. Design: Ten-month quality improvement collaborative....

» Incidence and Outcomes of Acute Laryngeal Injury After Prolonged Mechanical Ventilation*
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: Upper airway injury is a recognized complication of prolonged endotracheal intubation, yet little attention has been paid to the consequences of laryngeal injury and functional impact. The purpose of our study was to prospect...

» Early Palliative Care Consultation in the Medical ICU: A Cluster Randomized Crossover Trial
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: To assess the impact of early triggered palliative care consultation on the outcomes of high-risk ICU patients. Design: Single-center cluster randomized crossover trial. Setting: Two medical ICUs at Barnes Jewish Hospital. Pa...

» Perceptions of Ethical Decision-Making Climate Among Clinicians Working in European and U.S. ICUs: Differences Between Nurses and Physicians*
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: To examine perceptions of nurses and physicians in regard to ethical decision-making climate in the ICU and to test the hypothesis that the worse the ethical decision-making climate, the greater the discordance between nurses...

» Host-Response Subphenotypes Offer Prognostic Enrichment in Patients With or at Risk for Acute Respiratory Distress Syndrome*
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: Classification of patients with acute respiratory distress syndrome into hyper- and hypoinflammatory subphenotypes using plasma biomarkers may facilitate more effective targeted therapy. We examined whether established subphe...

» Vasopressin Versus Norepinephrine for the Management of Septic Shock in Cancer Patients: The VANCS II Randomized Clinical Trial*
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: Previous trials suggest that vasopressin may improve outcomes in patients with vasodilatory shock. The aim of this study was to evaluate whether vasopressin could be superior to norepinephrine to improve outcomes in cancer pa...

» Ramelteon for Prevention of Postoperative Delirium: A Randomized Controlled Trial in Patients Undergoing Elective Pulmonary Thromboendarterectomy*
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: To assess the efficacy of ramelteon in preventing delirium, an acute neuropsychiatric condition associated with increased morbidity and mortality, in the perioperative, ICU setting. Design: Parallel-arm, randomized, double-bl...

» Family-Centered Care in the ICU: Strength in Numbers*
01/12/19 06:00 from Critical Care Medicine - Current Issue
No abstract available

» Ramelteon for ICU Delirium Prevention: Is It Time to Melt Away?*
01/12/19 06:00 from Critical Care Medicine - Current Issue
No abstract available

» Insights Into a “Negative” ICU Trial Derived From Gene Expression Profiling
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: Randomized controlled trials in the ICU often fail to show differences in endpoints between groups. We sought to explore reasons for this at a molecular level by analyzing transcriptomic data from a recent negative trial. Our...

» One-Year Prognosis of Kidney Injury at Discharge From the ICU: A Multicenter Observational Study
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: The association between outcome and kidney injury detected at discharge from the ICU using different biomarkers remains unknown. The objective was to evaluate the association between 1-year survival and kidney injury at ICU d...

» Preoperative Diaphragm Function Is Associated With Postoperative Pulmonary Complications After Cardiac Surgery
01/12/19 06:00 from Critical Care Medicine - Current Issue
Objectives: Postoperative pulmonary complications increase mortality, length, and cost of hospitalization. A better diaphragmatic strength may help face an increased work of breathing postoperatively. We, therefore, sought to determine i...