» Meningitis and encephalitis management in the ICU
01/10/19 05:00 from Current Opinion in Critical Care - Current Issue
Purpose of review Management of patients with meningitis and encephalitis oftentimes requires ICU level of care. This article is an update on management for meningitis and encephalitis with focus on clinical care in the ICU. Information ...

» Diagnosing invasive pulmonary aspergillosis in ICU patients: putting the puzzle together
01/10/19 05:00 from Current Opinion in Critical Care - Current Issue
Purpose of review The approach to diagnose invasive pulmonary aspergillosis in the absence of lung biopsy in ICU patients is reviewed. This approach should be based on four pillars: mycology, medical imaging, underlying conditions, and a...

» Severe influenza: overview in critically ill patients
01/10/19 05:00 from Current Opinion in Critical Care - Current Issue
Purpose of review Overview of influenza infection, focusing on outcome and complications in critically ill patients. We also discuss relevant elements in immunopathogenesis and their role as predictors of severity. Recent findings Pandem...

» Challenges in conducting long-term outcomes studies in critical care
01/10/19 05:00 from Current Opinion in Critical Care - Current Issue
Purpose of review Evaluating longer term mortality, morbidity, and quality of life in survivors of critical illness is a research priority. This review details the challenges of long-term follow-up studies of critically ill patients and ...

» Population enrichment for critical care trials: phenotypes and differential outcomes
01/10/19 05:00 from Current Opinion in Critical Care - Current Issue
Purpose of review Sepsis and acute respiratory distress syndrome (ARDS) are two heterogenous acute illnesses where numerous RCTs have indeterminate results. We present a narrative review on the recent developments in enriching patient po...

» In the pursuit of partnership: patient and family engagement in critical care medicine
01/10/19 05:00 from Current Opinion in Critical Care - Current Issue
Purpose of review Patient and family partnership in critical care medicine research and clinical care is essential to achieve patient and family-centered care. Although there is an increasing interest in patient and family engagement, re...

» Strategies to effect change in the ICU
01/10/19 05:00 from Current Opinion in Critical Care - Current Issue
Purpose of review To provide an update on implementation efforts in the care of critically ill patients, with a focus on work published in the last 2 years. Recent findings Only half of surveyed members of the multidisciplinary care team...

» Deadoption of low-value practices in the ICU
01/10/19 05:00 from Current Opinion in Critical Care - Current Issue
Purpose of review Change of practice in the ICU, particularly the discontinuation of approaches, which are no longer felt to be beneficial, can be challenging. This review will examine this issue and outline current thinking regarding ho...

» Historic review of long-term outcomes research
01/10/19 05:00 from Current Opinion in Critical Care - Current Issue
Purpose of review This review summarizes the results from long-term intensive care outcome research over the past 50 years. Key findings from early studies are reflected in citations of contemporary research. Recent findings The postinte...

» Clinical Examination for the Prediction of Mortality in the Critically Ill: The Simple Intensive Care Studies-I
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objectives: Caregivers use clinical examination to timely recognize deterioration of a patient, yet data on the prognostic value of clinical examination are inconsistent. In the Simple Intensive Care Studies-I, we evaluated the associati...

» Declining Mortality of Cirrhotic Variceal Bleeding Requiring Admission to Intensive Care: A Binational Cohort Study*
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objectives: We aimed to describe changes over time in admissions and outcomes, including length of stay, discharge destinations, and mortality of cirrhotic patients admitted to the ICU for variceal bleeding, and to compare it to the outc...

» A Core Outcome Set for Critical Care Ventilation Trials
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objectives: Our objective was to obtain international consensus on a set of core outcome measures that should be recorded in all clinical trials of interventions intended to modify the duration of ventilation for invasively mechanically ...

» Implementation of a Bundled Consent Process in the ICU: A Single-Center Experience*
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objectives: A bundled consent process, where patients or surrogates provide consent for all commonly performed procedures on a single form at the time of ICU admission, has been advocated as a method for improving both rates of documente...

» Randomized Clinical Trial of an ICU Recovery Pilot Program for Survivors of Critical Illness*
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objectives: To examine the effect of an interdisciplinary ICU recovery program on process measures and clinical outcomes. Design: A prospective, single-center, randomized pilot trial. Setting: Academic, tertiary-care medical center. Pati...

» Are Peripherally Inserted Central Catheters Suitable for Cardiac Output Assessment With Transpulmonary Thermodilution?*
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objectives: Peripherally inserted central catheters are increasingly used in ICU as an alternative to centrally inserted central catheters for IV infusion. However, their reliability for hemodynamic measurements with transpulmonary therm...

» End-of-Life Decision-Making for ICU Patients With Limited English Proficiency: A Qualitative Study of Healthcare Team Insights
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objectives: Research indicates that the increasing population of over 25 million people in the United States who have limited English proficiency experience differences in decision-making and subsequent care at end of life in the ICU whe...

» Association Between the Use of Sodium Bicarbonate and Mortality in Acute Kidney Injury Using Marginal Structural Cox Model
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objective: Acute kidney injury with metabolic acidosis is common in critically ill patients. This study assessed the associations between the use of IV sodium bicarbonate and mortality of patients with acute kidney injury and acidosis. D...

» Outcome Prediction in Postanoxic Coma With Deep Learning*
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objectives: Visual assessment of the electroencephalogram by experienced clinical neurophysiologists allows reliable outcome prediction of approximately half of all comatose patients after cardiac arrest. Deep neural networks hold promis...

» Nurse Practitioners and Physician Assistants in Acute and Critical Care: A Concise Review of the Literature and Data 2008–2018
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objectives: To provide a concise review of the literature and data pertaining to the use of nurse practitioners and physician assistants, collectively called advanced practice providers, in ICU and acute care settings. Data Sources: Deta...

» Lactated Ringer’s Versus 4% Albumin on Lactated Ringer’s in Early Sepsis Therapy in Cancer Patients: A Pilot Single-Center Randomized Trial
01/10/19 05:00 from Critical Care Medicine - Current Issue
Objective: To investigate the effects of the administration of 4% albumin on lactated Ringer’s, when compared with lactated Ringer’s alone, in the early phase of sepsis in cancer patients. Design: Single-center, randomized, double-blind,...