» Early Surge in Brain GFAP Distribution in Female Hamsters With Mild Peripheral COVID-19
22/05/26 20:00 from coronavirus
Mild to moderate respiratory COVID-19 is commonly associated with a range of neurological symptoms. The two primary proposed mechanisms linking this primarily peripheral disease to the brain, include brain entry of peripheral circulating...

» Does previous COVID-19 severity affect propofol sedation safety during ERCP?: A prospective observational study
22/05/26 20:00 from coronavirus
Endoscopic retrograde cholangiopancreatography (ERCP) requires deep sedation, typically with propofol, because of its rapid onset and recovery time. However, propofol can cause respiratory and hemodynamic instability. Because Coronavirus...

» The impact of the COVID-19 pandemic in 2020 on the diagnosis, treatment, and cancer-specific survival of major urological cancers: An observational study
22/05/26 20:00 from coronavirus
The impact of the COVID-19 pandemic in 2020 on the diagnosis, treatment, and outcomes of major urological cancers remains poorly understood. Patients diagnosed with prostate cancer, bladder cancer, and kidney cancer were identified from ...

» Breastfeeding May Confer Long-Term Immunity Against Emerging Infectious Pathogens-Ecological Evidence over 2 Full Years of the COVID-19 Epidemic in Georgia, United States
22/05/26 20:00 from covid-19
CONCLUSIONS: A significantly higher COVID-19 incidence occurred in low BFIR counties compared to that in high BFIR counties. Breastfeeding may confer long-term immunity against emerging infectious pathogens by enhancing an individual's b...

» Post COVID-19 treated with AstraZeneca vaccine exacerbates arthritis with susceptibility to herpes in an older woman: A case report
22/05/26 20:00 from coronavirus
RATIONALE: Rheumatoid arthritis (RA) is an autoimmune inflammatory disorder that has seriously affected human health worldwide. This report describes a rare case of herpes infection, secondary to RA, that emerged after coronavirus diseas...

» The COVID-19 Pandemic and the 2022 Formula Shortage: Associations with Breastfeeding Initiation over 5 Years in the State of Florida, United States
22/05/26 20:00 from covid-19
CONCLUSION: The combined pressures of COVID-19 pandemic and formula scarcity increased breastfeeding initiation rates, especially in WIC beneficiaries. However, breastfeeding initiation rates returned to prepandemic levels as the formula...

» Tech-based evaluation of healthcare quality during the COVID-19 pandemic
22/05/26 20:00 from coronavirus
The coronavirus disease 2019 pandemic profoundly disrupted global health systems, exacerbating preexisting inequalities in access to and quality of care. Disparities in service accessibility, continuity, coordination, and comprehensivene...

» Early Surge in Brain GFAP Distribution in Female Hamsters With Mild Peripheral COVID-19
22/05/26 20:00 from sars-cov-2
Mild to moderate respiratory COVID-19 is commonly associated with a range of neurological symptoms. The two primary proposed mechanisms linking this primarily peripheral disease to the brain, include brain entry of peripheral circulating...

» Early Surge in Brain GFAP Distribution in Female Hamsters With Mild Peripheral COVID-19
22/05/26 20:00 from covid-19
Mild to moderate respiratory COVID-19 is commonly associated with a range of neurological symptoms. The two primary proposed mechanisms linking this primarily peripheral disease to the brain, include brain entry of peripheral circulating...

» Occupational and lifestyle associations with mental health of healthcare workers
22/05/26 20:00 from coronavirus
Mental disorders are a leading cause of morbidity worldwide, and healthcare professionals are particularly vulnerable due to occupational stressors, a vulnerability intensified during the coronavirus disease 2019 pandemic. This study ass...

» Does previous COVID-19 severity affect propofol sedation safety during ERCP?: A prospective observational study
22/05/26 20:00 from covid-19
Endoscopic retrograde cholangiopancreatography (ERCP) requires deep sedation, typically with propofol, because of its rapid onset and recovery time. However, propofol can cause respiratory and hemodynamic instability. Because Coronavirus...

» Does previous COVID-19 severity affect propofol sedation safety during ERCP?: A prospective observational study
22/05/26 20:00 from sars-cov-2
Endoscopic retrograde cholangiopancreatography (ERCP) requires deep sedation, typically with propofol, because of its rapid onset and recovery time. However, propofol can cause respiratory and hemodynamic instability. Because Coronavirus...

» Semantic Harmonization Workflow of Health Data: Application in the Post-COVID Network Netherlands
22/05/26 20:00 from coronavirus
Semantic interoperability in multi-source health datasets is a key barrier to data integration and reuse in biomedical research. FAIR principles promote standardization, but operationalizing them for heterogeneous clinical and patient-re...

» Early Surge in Brain GFAP Distribution in Female Hamsters With Mild Peripheral COVID-19
22/05/26 20:00 from Cell entry mechanisms of SARS-CoV-2
Mild to moderate respiratory COVID-19 is commonly associated with a range of neurological symptoms. The two primary proposed mechanisms linking this primarily peripheral disease to the brain, include brain entry of peripheral circulating...

» The impact of the COVID-19 pandemic in 2020 on the diagnosis, treatment, and cancer-specific survival of major urological cancers: An observational study
22/05/26 20:00 from covid-19
The impact of the COVID-19 pandemic in 2020 on the diagnosis, treatment, and outcomes of major urological cancers remains poorly understood. Patients diagnosed with prostate cancer, bladder cancer, and kidney cancer were identified from ...

» The impact of the COVID-19 pandemic in 2020 on the diagnosis, treatment, and cancer-specific survival of major urological cancers: An observational study
22/05/26 20:00 from sars-cov-2
The impact of the COVID-19 pandemic in 2020 on the diagnosis, treatment, and outcomes of major urological cancers remains poorly understood. Patients diagnosed with prostate cancer, bladder cancer, and kidney cancer were identified from ...

» Long Covid and Digital Health in Switzerland: Potentials and Limitations
22/05/26 20:00 from coronavirus
Post-COVID-19 (or Long Covid) presents a complex and persistent health challenge affecting a growing number of individuals worldwide. Digital health interventions (DHIs) offer potential support for symptom monitoring, self-management, an...

» Post COVID-19 treated with AstraZeneca vaccine exacerbates arthritis with susceptibility to herpes in an older woman: A case report
22/05/26 20:00 from covid-19
RATIONALE: Rheumatoid arthritis (RA) is an autoimmune inflammatory disorder that has seriously affected human health worldwide. This report describes a rare case of herpes infection, secondary to RA, that emerged after coronavirus diseas...

» Post COVID-19 treated with AstraZeneca vaccine exacerbates arthritis with susceptibility to herpes in an older woman: A case report
22/05/26 20:00 from sars-cov-2
RATIONALE: Rheumatoid arthritis (RA) is an autoimmune inflammatory disorder that has seriously affected human health worldwide. This report describes a rare case of herpes infection, secondary to RA, that emerged after coronavirus diseas...

» Predicting COVID-19 Vaccination Decision-Making Profiles Among Dutch Adults: From Survey to National Administrative Data
22/05/26 20:00 from coronavirus
Individual's vaccination behaviors are influenced by factors such as values and beliefs. Applying latent class analysis (LCA) to such factors from the Longitudinal Internet Studies for the Social Sciences (LISS) panel[1], Matthijssen et ...

» Tech-based evaluation of healthcare quality during the COVID-19 pandemic
22/05/26 20:00 from covid-19
The coronavirus disease 2019 pandemic profoundly disrupted global health systems, exacerbating preexisting inequalities in access to and quality of care. Disparities in service accessibility, continuity, coordination, and comprehensivene...

» Tech-based evaluation of healthcare quality during the COVID-19 pandemic
22/05/26 20:00 from sars-cov-2
The coronavirus disease 2019 pandemic profoundly disrupted global health systems, exacerbating preexisting inequalities in access to and quality of care. Disparities in service accessibility, continuity, coordination, and comprehensivene...

» Social Isolation, Social Capitals, and Quality of Life Among the Elderly During the COVID-19 Pandemic in the Northeast of Thailand
22/05/26 20:00 from coronavirus
This cross-sectional study examined the relationships among social isolation, social capitals, and QoL among older adults in Northeastern Thailand during the COVID-19 pandemic. A multi-stage stratified random sampling were used to select...

» Occupational and lifestyle associations with mental health of healthcare workers
22/05/26 20:00 from covid-19
Mental disorders are a leading cause of morbidity worldwide, and healthcare professionals are particularly vulnerable due to occupational stressors, a vulnerability intensified during the coronavirus disease 2019 pandemic. This study ass...

» Occupational and lifestyle associations with mental health of healthcare workers
22/05/26 20:00 from sars-cov-2
Mental disorders are a leading cause of morbidity worldwide, and healthcare professionals are particularly vulnerable due to occupational stressors, a vulnerability intensified during the coronavirus disease 2019 pandemic. This study ass...

» Semantic Harmonization Workflow of Health Data: Application in the Post-COVID Network Netherlands
22/05/26 20:00 from covid-19
Semantic interoperability in multi-source health datasets is a key barrier to data integration and reuse in biomedical research. FAIR principles promote standardization, but operationalizing them for heterogeneous clinical and patient-re...

» A Mobile Research App for Post-COVID Fatigue Monitoring
22/05/26 20:00 from coronavirus
Post-COVID fatigue is a common and burdensome symptom that fluctuates throughout the day, making it difficult to assess within clinical visits. To capture post-COVID symptom fatigue in daily settings, we developed a mobile research app b...

» Semantic Harmonization Workflow of Health Data: Application in the Post-COVID Network Netherlands
22/05/26 20:00 from sars-cov-2
Semantic interoperability in multi-source health datasets is a key barrier to data integration and reuse in biomedical research. FAIR principles promote standardization, but operationalizing them for heterogeneous clinical and patient-re...

» Long Covid and Digital Health in Switzerland: Potentials and Limitations
22/05/26 20:00 from covid-19
Post-COVID-19 (or Long Covid) presents a complex and persistent health challenge affecting a growing number of individuals worldwide. Digital health interventions (DHIs) offer potential support for symptom monitoring, self-management, an...

» Usability of Digital Health Technologies in the US: Results from a Descriptive National Online Survey of Nurses
22/05/26 20:00 from coronavirus
The COVID-19 pandemic accelerated the use of digital technologies across healthcare systems, highlighting nurses' pivotal role in technology-enabled care. This paper reports findings from a US national descriptive survey conducted during...

» Long Covid and Digital Health in Switzerland: Potentials and Limitations
22/05/26 20:00 from sars-cov-2
Post-COVID-19 (or Long Covid) presents a complex and persistent health challenge affecting a growing number of individuals worldwide. Digital health interventions (DHIs) offer potential support for symptom monitoring, self-management, an...

» Predicting COVID-19 Vaccination Decision-Making Profiles Among Dutch Adults: From Survey to National Administrative Data
22/05/26 20:00 from covid-19
Individual's vaccination behaviors are influenced by factors such as values and beliefs. Applying latent class analysis (LCA) to such factors from the Longitudinal Internet Studies for the Social Sciences (LISS) panel[1], Matthijssen et ...

» Characterizing Real-World Data by Care Setting to Support Clinical Research
22/05/26 20:00 from coronavirus
Electronic Health Records (EHRs) are a main source of Real-World Data (RWD) for research, but heterogeneity across encounter types and geographical regions affects data completeness. This study characterizes clinical data from 110 Health...

» Predicting COVID-19 Vaccination Decision-Making Profiles Among Dutch Adults: From Survey to National Administrative Data
22/05/26 20:00 from sars-cov-2
Individual's vaccination behaviors are influenced by factors such as values and beliefs. Applying latent class analysis (LCA) to such factors from the Longitudinal Internet Studies for the Social Sciences (LISS) panel[1], Matthijssen et ...

» Social Isolation, Social Capitals, and Quality of Life Among the Elderly During the COVID-19 Pandemic in the Northeast of Thailand
22/05/26 20:00 from covid-19
This cross-sectional study examined the relationships among social isolation, social capitals, and QoL among older adults in Northeastern Thailand during the COVID-19 pandemic. A multi-stage stratified random sampling were used to select...

» Fragment-Based Design of Targeted Covalent Inhibitors: The Scope and Limitation of Linking Approaches
22/05/26 20:00 from coronavirus
Linking of fragments in neighboring binding sites is one of the optimization strategies in fragment-based drug discovery, where additive or even more substantial bioactivity improvements can be realized. However, such efforts present a c...

» Social Isolation, Social Capitals, and Quality of Life Among the Elderly During the COVID-19 Pandemic in the Northeast of Thailand
22/05/26 20:00 from sars-cov-2
This cross-sectional study examined the relationships among social isolation, social capitals, and QoL among older adults in Northeastern Thailand during the COVID-19 pandemic. A multi-stage stratified random sampling were used to select...

» Kernel Density Estimation of Wearable Signals to Predict Preoperative Cancellation Risk
22/05/26 20:00 from covid-19
Digital health approaches that leverage consumer wearables and machine learning offer scalable means to detect acute illness pre-symptomatically, enabling earlier intervention and improved resource planning. Prior studies have shown that...

» A systematic scoping review and conceptual analysis of new-onset fibromyalgia manifestations after non-hospitalized COVID-19: empirics, definitions, methodologies, pathophysiology, mapping of literature, and knowledge gaps
22/05/26 20:00 from coronavirus
BACKGROUND: The global coronavirus pandemic has led to a quiet wave of a chronic illness referred to as 'Long/Post Covid-19 syndrome' (LC) which bears a notable resemblance to functional-somatic or 'fibromyalgia-type' syndromes, and whos...

» A Mobile Research App for Post-COVID Fatigue Monitoring
22/05/26 20:00 from sars-cov-2
Post-COVID fatigue is a common and burdensome symptom that fluctuates throughout the day, making it difficult to assess within clinical visits. To capture post-COVID symptom fatigue in daily settings, we developed a mobile research app b...

» A Mobile Research App for Post-COVID Fatigue Monitoring
22/05/26 20:00 from covid-19
Post-COVID fatigue is a common and burdensome symptom that fluctuates throughout the day, making it difficult to assess within clinical visits. To capture post-COVID symptom fatigue in daily settings, we developed a mobile research app b...

» Usability of Digital Health Technologies in the US: Results from a Descriptive National Online Survey of Nurses
22/05/26 20:00 from sars-cov-2
The COVID-19 pandemic accelerated the use of digital technologies across healthcare systems, highlighting nurses' pivotal role in technology-enabled care. This paper reports findings from a US national descriptive survey conducted during...

» Usability of Digital Health Technologies in the US: Results from a Descriptive National Online Survey of Nurses
22/05/26 20:00 from covid-19
The COVID-19 pandemic accelerated the use of digital technologies across healthcare systems, highlighting nurses' pivotal role in technology-enabled care. This paper reports findings from a US national descriptive survey conducted during...

» Characterizing Real-World Data by Care Setting to Support Clinical Research
22/05/26 20:00 from sars-cov-2
Electronic Health Records (EHRs) are a main source of Real-World Data (RWD) for research, but heterogeneity across encounter types and geographical regions affects data completeness. This study characterizes clinical data from 110 Health...

» Fragment-Based Design of Targeted Covalent Inhibitors: The Scope and Limitation of Linking Approaches
22/05/26 20:00 from sars-cov-2
Linking of fragments in neighboring binding sites is one of the optimization strategies in fragment-based drug discovery, where additive or even more substantial bioactivity improvements can be realized. However, such efforts present a c...

» A systematic scoping review and conceptual analysis of new-onset fibromyalgia manifestations after non-hospitalized COVID-19: empirics, definitions, methodologies, pathophysiology, mapping of literature, and knowledge gaps
22/05/26 20:00 from sars-cov-2
BACKGROUND: The global coronavirus pandemic has led to a quiet wave of a chronic illness referred to as 'Long/Post Covid-19 syndrome' (LC) which bears a notable resemblance to functional-somatic or 'fibromyalgia-type' syndromes, and whos...

» A hypothesized mechanism by which inhaled low-concentration ethanol vapor may bias early entry dynamics of enveloped respiratory viruses
21/05/26 20:00 from Cell entry mechanisms of SARS-CoV-2
Enveloped respiratory viruses rely on conserved biophysical properties of their lipid envelopes for successful host-cell entry, including membrane fluidity, spike conformational mobility, and coordinated fusion activation. These properti...

» Ligand-Based Pharmacophore Modeling and Structure-Based Virtual Screening for Identifying Potential Therapeutic Agents Targeting the SARS-CoV-2 Spike Protein-ACE2 Receptor Interaction
21/05/26 20:00 from sars-cov-2 spike protein
Coronavirus disease (COVID-19) remains a global health concern due to its high mortality and morbidity. In this study, we combined ligand-based pharmacophore modeling (LBPM) with structure-based virtual screening (SBVS) to identify novel...

» Simultaneous quantification of anti-Spike IgG subclasses against various SARS-CoV-2 variants using a multiplex serological assay
21/05/26 20:00 from sars-cov-2 spike protein
Recent research indicates that the composition of serum anti-SARS-CoV-2 Spike IgG subclass antibodies changes upon repeated exposure to viral Spike. These antibody subclass dynamics were suggested to impact adaptive immune responses and ...

» Extending the Targets for Coronavirus Antivirals Beyond That of Approved Drugs: Insights From Preclinical Research
21/05/26 20:00 from sars-cov-2 spike protein
Antiviral drugs have been approved for the treatment of COVID-19. However, they present pharmacological limitations, a mixed efficacy profile and target just two coronavirus proteins. To extend the range of druggable coronavirus proteins...

» Catch-up and life-course vaccination policies for adult and adolescent migrants in low-and-middle income countries: A policy analysis
21/05/26 20:00 from Covid-19 origins
CONCLUSION: Most LMICs lack policies ensuring adolescent and adult migrants access catch-up and life-course vaccination, despite ample evidence that these are under-immunised populations. Governments should clarify entitlements, adopt mi...

» Factors influencing work ability and return-to-work in individuals affected by post-COVID: a systematic review
21/05/26 20:00 from Covid-19 origins
CONCLUSIONS: Work ability and RTW with post-COVID is determined by complex multilevel interactions of biopsychosocial, workplace-related, and systemic factors. Findings suggest that coordinated care and workplace adaptations may help to ...

» A randomized controlled trial of adjunctive speleotherapy in asthma, COPD and long COVID
21/05/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
Speleotherapy (underground climate therapy) is a non-pharmacological intervention for chronic respiratory diseases. This randomized controlled trial investigated whether a 3-week speleotherapy course (6 sessions, 2 h/week) improves respi...

» Pandemic-Related Disruptions and Hepatocellular Carcinoma Surveillance in Safety-Net Settings
21/05/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS AND RELEVANCE: In this observational study of US safety-net populations with cirrhosis, rates of HCC surveillance following pandemic-related declines remained persistently low even up to 4 years after the onset of the COVID-1...

» Factors influencing work ability and return-to-work in individuals affected by post-COVID: a systematic review
21/05/26 20:00 from Sars-Cov-2 origins
CONCLUSIONS: Work ability and RTW with post-COVID is determined by complex multilevel interactions of biopsychosocial, workplace-related, and systemic factors. Findings suggest that coordinated care and workplace adaptations may help to ...

» Polystyrene Microplastic-Induced Cellular Alterations and Their Effects on Viral Entry (RSV, HCoV-OC43, EV-A71) and Viral Persistence
20/05/26 20:00 from coronavirus
Microplastics (MPs) are emerging environmental pollutants with biological impacts extending beyond cytotoxicity, yet their interactions with viruses remain poorly understood. This study systematically investigated the cellular and virolo...

» COVID-19, the disease that changed the world
20/05/26 20:00 from Sars-Cov-2 origins
Five years ago, the COVID-19 coronavirus emerged as an invisible threat that profoundly disrupted the world, becoming a public health challenge. The COVID-19 pandemic has shown us how important it is to have health systems that can quick...

» Rapid Response in Graduate Training in Public Health Preparedness to the COVID-19 Pandemic: The Experience of Penn State University
20/05/26 20:00 from sars-cov-2
CONCLUSIONS: Penn State responded to the COVID-19 pandemic with an innovative course that developed students' real-time understanding of pandemic response. Students gained knowledge and skills relevant to the practice of public health. B...

» Organoids: From Bench to Bedside Applications
20/05/26 20:00 from coronavirus
Organoids are three-dimensiona(3D) models derived from stem cells that closely replicate the structure and cellular complexity of human tissues, providing physiologically relevant platforms for biomedical research. This technology addres...

» COVID-19, the disease that changed the world
20/05/26 20:00 from coronavirus
Five years ago, the COVID-19 coronavirus emerged as an invisible threat that profoundly disrupted the world, becoming a public health challenge. The COVID-19 pandemic has shown us how important it is to have health systems that can quick...

» Preclinical evaluation of a multi-epitope mRNA vaccine platform for broad and durable SARS-CoV-2 protection
20/05/26 20:00 from coronavirus
INTRODUCTION: The emergence of immune-evasive SARS-CoV-2 variants has exposed limitations in the breadth and durability of protection conferred by current Spike-based vaccines, highlighting the need for next-generation approaches targeti...

» Organoids: From Bench to Bedside Applications
20/05/26 20:00 from sars-cov-2
Organoids are three-dimensiona(3D) models derived from stem cells that closely replicate the structure and cellular complexity of human tissues, providing physiologically relevant platforms for biomedical research. This technology addres...

» Coronavirus diversity and SARS-CoV-2 exposure at the wildlife-human interface in Northern Italy
20/05/26 20:00 from Sars-Cov-2 origins
CONCLUSIONS: This study provides an overview of CoVs circulation among wild mammals in RER, supporting the role of hedgehogs as reservoirs and identifying some species with evidence of exposure to SARS-CoV-2. Certain unexpected findings ...

» Transforming postoperative follow-up: telemedicine trends in radical prostatectomy patients
20/05/26 20:00 from coronavirus
CONCLUSIONS: Telemedicine offers an effective and patient centric method of surveillance after RP. Targeted efforts are needed to address sociodemographic factors that influence its utilization.

» COVID-19, the disease that changed the world
20/05/26 20:00 from sars-cov-2
Five years ago, the COVID-19 coronavirus emerged as an invisible threat that profoundly disrupted the world, becoming a public health challenge. The COVID-19 pandemic has shown us how important it is to have health systems that can quick...

» Guillain-Barre Syndrome Following Seasonal Coronavirus (HCoV-229E) Infection: A Case Managed Without Intensive Care
20/05/26 20:00 from coronavirus
Guillain-Barré syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy often preceded by infection. We report the case of a 49-year-old man presenting with subacute, progressive, symmetric ascending weakness involving the lower...

» Preclinical evaluation of a multi-epitope mRNA vaccine platform for broad and durable SARS-CoV-2 protection
20/05/26 20:00 from sars-cov-2
INTRODUCTION: The emergence of immune-evasive SARS-CoV-2 variants has exposed limitations in the breadth and durability of protection conferred by current Spike-based vaccines, highlighting the need for next-generation approaches targeti...

» Genetic Diversity, Recombination, and Pathogenicity of Porcine Epidemic Diarrhea Virus Strains Circulating in China During 2023-2024
20/05/26 20:00 from coronavirus
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal piglets, posing a persistent threat to the global swine industry. Despite extensive vaccination, PEDV contin...

» Frequency and Demographic Patterns of SARS-CoV-2 and Influenza Virus Infections in Khuzestan: A Retrospective Observational Study (2021-2023)
20/05/26 20:00 from sars-cov-2
CONCLUSION: The present study demonstrates a declining trend of SARS-CoV-2 infection alongside a progressive rise in influenza cases in southwest Iran from 2021 to 2023. The findings highlight age- and sex-related variations in infection...

» Frequency and Demographic Patterns of SARS-CoV-2 and Influenza Virus Infections in Khuzestan: A Retrospective Observational Study (2021-2023)
20/05/26 20:00 from coronavirus
CONCLUSION: The present study demonstrates a declining trend of SARS-CoV-2 infection alongside a progressive rise in influenza cases in southwest Iran from 2021 to 2023. The findings highlight age- and sex-related variations in infection...

» Seroprevalence of Coronavirus NL63 in Yamagata, Japan, Between 1976 and 2022
20/05/26 20:00 from coronavirus
Advances in the epidemiology of seasonal coronavirus (CoV) are important for understanding CoV transmission dynamics and strengthening the strategies against emerging CoV infections. The epidemiology of CoV-NL63, a seasonal CoV discovere...

» Depression, anxiety, and stress among adults in Kuwait across pre- and post-vaccine phases of the COVID-19 pandemic: a repeated cross-sectional study
20/05/26 20:00 from coronavirus
CONCLUSION: Substantial mental health challenges were observed in both pre- and post-vaccine phases of the pandemic, particularly among women, younger adults, and non-citizens. Protective coping strategies, especially faith-based and soc...

» The next phase in Long COVID research: addressing the ethical challenges in trials of disease-modifying treatments
20/05/26 20:00 from sars-cov-2
Almost five years after COVID-19 emerged, multiple scientific uncertainties remain about why some people experience ongoing symptoms long after being infected with SARS-CoV-2 (Long COVID). The pathophysiology underlying Long COVID and it...

» Application of Label-Free Detection Using Tapered Optical Fiber System for Head and Neck Cancer and Infectious Biomolecules
20/05/26 20:00 from coronavirus
CONCLUSION: This study demonstrates the feasibility of TOFS as a rapid, portable, and potentially low-cost sensing platform for biomarker and pathogen detection. Further validation in clinically derived specimens is warranted to define i...

» Depression, anxiety, and stress among adults in Kuwait across pre- and post-vaccine phases of the COVID-19 pandemic: a repeated cross-sectional study
20/05/26 20:00 from sars-cov-2
CONCLUSION: Substantial mental health challenges were observed in both pre- and post-vaccine phases of the pandemic, particularly among women, younger adults, and non-citizens. Protective coping strategies, especially faith-based and soc...

» Coronavirus diversity and SARS-CoV-2 exposure at the wildlife-human interface in Northern Italy
20/05/26 20:00 from coronavirus
CONCLUSIONS: This study provides an overview of CoVs circulation among wild mammals in RER, supporting the role of hedgehogs as reservoirs and identifying some species with evidence of exposure to SARS-CoV-2. Certain unexpected findings ...

» The impact of COVID-19 on illegitimate tasks across occupations in Sweden: a longitudinal observational study
20/05/26 20:00 from coronavirus
CONCLUSIONS: The level of illegitimate work varies across different occupations, with a higher prevalence in female-dominated, human service fields compared to male-dominated technical roles. Addressing the growing care needs with more h...

» Coronavirus diversity and SARS-CoV-2 exposure at the wildlife-human interface in Northern Italy
20/05/26 20:00 from sars-cov-2
CONCLUSIONS: This study provides an overview of CoVs circulation among wild mammals in RER, supporting the role of hedgehogs as reservoirs and identifying some species with evidence of exposure to SARS-CoV-2. Certain unexpected findings ...

» Genetic Diversity, Recombination, and Pathogenicity of Porcine Epidemic Diarrhea Virus Strains Circulating in China During 2023-2024
20/05/26 20:00 from covid-19 and viral infections in pigs
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal piglets, posing a persistent threat to the global swine industry. Despite extensive vaccination, PEDV contin...

» Relapse of HIV-associated multicentric Castleman disease temporally associated with acute coronavirus disease 2019: a case report
20/05/26 20:00 from coronavirus
CONCLUSION: This case is the first to report a temporal association between SARS-CoV-2 infection and HIV-MCD relapse. While a direct causal relationship cannot be established, the clinical course is consistent with the hypothesis that SA...

» Primary care physicians' perspectives on managing mild-to-moderate COVID-19 in populations at risk for progression to severe disease: a survey-based study
20/05/26 20:00 from coronavirus
CONCLUSIONS: Our study demonstrated gaps in knowledge and awareness regarding COVID-19 burden, treatment, antiviral medications, guidelines for managing mild-to-severe disease, and the handling of relevant drug-drug interactions. These f...

» The impact of COVID-19 on illegitimate tasks across occupations in Sweden: a longitudinal observational study
20/05/26 20:00 from sars-cov-2
CONCLUSIONS: The level of illegitimate work varies across different occupations, with a higher prevalence in female-dominated, human service fields compared to male-dominated technical roles. Addressing the growing care needs with more h...

» Whole genome sequencing of SARS-CoV-2: evaluating the genetic diversity of variants circulating in Ebonyi State, Southeastern Nigeria
20/05/26 20:00 from sars-cov-2
CONCLUSIONS: This study highlighted the dynamics of the circulating SARS-CoV-2 strains in Nigeria. Information from this study will be very crucial in developing and structuring interventions, adaptation of response strategies, and impro...

» Rapid Response in Graduate Training in Public Health Preparedness to the COVID-19 Pandemic: The Experience of Penn State University
20/05/26 20:00 from covid-19
CONCLUSIONS: Penn State responded to the COVID-19 pandemic with an innovative course that developed students' real-time understanding of pandemic response. Students gained knowledge and skills relevant to the practice of public health. B...

» SARS-CoV-2 seroprevalence among pregnant women during the first three waves of the COVID-19 pandemic in southern Mozambique
20/05/26 20:00 from sars-cov-2
CONCLUSIONS: The study reported a rising seroprevalence for antibodies to SARS-CoV-2 in pregnancy, particularly in the third wave when the Omicron variant predominated. In a subsample, the prevalence of SARS-CoV-2 in maternal serum was s...

» Relapse of HIV-associated multicentric Castleman disease temporally associated with acute coronavirus disease 2019: a case report
20/05/26 20:00 from sars-cov-2
CONCLUSION: This case is the first to report a temporal association between SARS-CoV-2 infection and HIV-MCD relapse. While a direct causal relationship cannot be established, the clinical course is consistent with the hypothesis that SA...

» COVID-19, the disease that changed the world
20/05/26 20:00 from Covid-19 origins
Five years ago, the COVID-19 coronavirus emerged as an invisible threat that profoundly disrupted the world, becoming a public health challenge. The COVID-19 pandemic has shown us how important it is to have health systems that can quick...

» Patients' Experiences of a Virtual Nursing Model in an Acute Care Setting: A Mixed-Methods Study
20/05/26 20:00 from sars-cov-2
CONCLUSIONS: The study findings offer confirmation that the expansion of virtual nursing models into medical-surgical acute care settings is associated with improved patient experiences. Many patients reported that they appreciated the v...

» Collaboration Networks, Trends, and Scientific Impact in Avoidable Mortality Research (2000-2024): A Bibliometric Study
20/05/26 20:00 from covid-19
CONCLUSION: This bibliometric analysis demonstrates a rising interest in avoidable mortality, reflected in increased scientific output and limited intergroup connectivity within international collaboration networks. Only a limited number...

» COVID-19, the disease that changed the world
20/05/26 20:00 from Coronavirus origins
Five years ago, the COVID-19 coronavirus emerged as an invisible threat that profoundly disrupted the world, becoming a public health challenge. The COVID-19 pandemic has shown us how important it is to have health systems that can quick...

» Global prevalence of prolonged grief disorder during the COVID-19 pandemic under standardized diagnostic frameworks: A systematic review and meta-analysis
20/05/26 20:00 from covid-19
Prolonged grief disorder (PGD), recently classified in ICD-11 and DSM-5-TR, is characterized by persistent and functionally impairing grief lasting beyond 6-12 months. The COVID-19 pandemic was accompanied by widespread mortality, social...

» Coronavirus diversity and SARS-CoV-2 exposure at the wildlife-human interface in Northern Italy
20/05/26 20:00 from Covid-19 origins
CONCLUSIONS: This study provides an overview of CoVs circulation among wild mammals in RER, supporting the role of hedgehogs as reservoirs and identifying some species with evidence of exposure to SARS-CoV-2. Certain unexpected findings ...

» Impact of COVID-19 pandemic on autism spectrum disorder service providers in Qatar: challenges, insights, and lessons learned
20/05/26 20:00 from covid-19
CONCLUSION: These findings suggest the importance of adaptive service delivery systems that maintain continuity of care during crises. Strengthening autism service infrastructure and developing resilient models are essential to safeguard...

» Preclinical evaluation of a multi-epitope mRNA vaccine platform for broad and durable SARS-CoV-2 protection
20/05/26 20:00 from sars-cov-2 spike protein
INTRODUCTION: The emergence of immune-evasive SARS-CoV-2 variants has exposed limitations in the breadth and durability of protection conferred by current Spike-based vaccines, highlighting the need for next-generation approaches targeti...

» Coronavirus diversity and SARS-CoV-2 exposure at the wildlife-human interface in Northern Italy
20/05/26 20:00 from Coronavirus origins
CONCLUSIONS: This study provides an overview of CoVs circulation among wild mammals in RER, supporting the role of hedgehogs as reservoirs and identifying some species with evidence of exposure to SARS-CoV-2. Certain unexpected findings ...

» Polystyrene Microplastic-Induced Cellular Alterations and Their Effects on Viral Entry (RSV, HCoV-OC43, EV-A71) and Viral Persistence
20/05/26 20:00 from covid-19
Microplastics (MPs) are emerging environmental pollutants with biological impacts extending beyond cytotoxicity, yet their interactions with viruses remain poorly understood. This study systematically investigated the cellular and virolo...

» Multi-Omic, Multi-Tissue Responses to Acute Exercise in Sedentary Adults: Findings from the Molecular Transducers of Physical Activity Consortium
20/05/26 20:00 from covid-19
Regular physical activity represents one of the greatest mechanisms for maintaining human health, yet the underlying molecular transducers of these benefits remain incompletely understood. Multi-omic assays now provide new opportunities ...

» Organoids: From Bench to Bedside Applications
20/05/26 20:00 from covid-19
Organoids are three-dimensiona(3D) models derived from stem cells that closely replicate the structure and cellular complexity of human tissues, providing physiologically relevant platforms for biomedical research. This technology addres...

» Feasibility of Delivering Facing Your Fears via Telehealth for Autistic Adolescents During the COVID-19 Pandemic
20/05/26 20:00 from covid-19
CONCLUSIONS: Despite limitations, findings suggest that the telehealth adaptation of FYF was an important resource during the COVID-19 pandemic for adolescents with autism and anxiety. Future research should incorporate participant feedb...

» COVID-19, the disease that changed the world
20/05/26 20:00 from covid-19
Five years ago, the COVID-19 coronavirus emerged as an invisible threat that profoundly disrupted the world, becoming a public health challenge. The COVID-19 pandemic has shown us how important it is to have health systems that can quick...

» Preclinical evaluation of a multi-epitope mRNA vaccine platform for broad and durable SARS-CoV-2 protection
20/05/26 20:00 from covid-19
INTRODUCTION: The emergence of immune-evasive SARS-CoV-2 variants has exposed limitations in the breadth and durability of protection conferred by current Spike-based vaccines, highlighting the need for next-generation approaches targeti...

» Transforming postoperative follow-up: telemedicine trends in radical prostatectomy patients
20/05/26 20:00 from covid-19
CONCLUSIONS: Telemedicine offers an effective and patient centric method of surveillance after RP. Targeted efforts are needed to address sociodemographic factors that influence its utilization.

» Guillain-Barre Syndrome Following Seasonal Coronavirus (HCoV-229E) Infection: A Case Managed Without Intensive Care
20/05/26 20:00 from covid-19
Guillain-Barré syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy often preceded by infection. We report the case of a 49-year-old man presenting with subacute, progressive, symmetric ascending weakness involving the lower...

» Wunderlich Syndrome: A Rare Case of Spontaneous Perinephric Hemorrhage
20/05/26 20:00 from covid-19
Wunderlich syndrome is a rare urological emergency characterized by spontaneous, nontraumatic renal hemorrhage into the subcapsular and perirenal spaces. We present the case of a 37-year-old male with end-stage renal disease on hemodialy...

» Domestic Violence and Quality of Life Among Pregnant Women During Covid-19 in Remote Areas of Indonesia
20/05/26 20:00 from covid-19
CONCLUSION: DV negatively impacts the QoL of pregnant women during the COVID-19 pandemic These findings highlight the need for strengthened policies, including routine psychological screening, counseling services, and the integration of ...

» Genetic Diversity, Recombination, and Pathogenicity of Porcine Epidemic Diarrhea Virus Strains Circulating in China During 2023-2024
20/05/26 20:00 from covid-19
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal piglets, posing a persistent threat to the global swine industry. Despite extensive vaccination, PEDV contin...

» Virologist accused of starting COVID-19 fights funding ban
20/05/26 20:00 from sars-cov-2
United States seeks to debar Ralph Baric for misleading NIAID on old coronavirus studies, which he disputes.

» Virologist accused of starting COVID-19 fights funding ban
20/05/26 20:00 from coronavirus
United States seeks to debar Ralph Baric for misleading NIAID on old coronavirus studies, which he disputes.

» The epidemiology of SARS-CoV-2, Influenza, and Respiratory Syncytial Virus circulation among adult patients with acute respiratory illness in Kampala Metropolitan Area in Uganda
20/05/26 20:00 from coronavirus
CONCLUSION: The co-circulation of SARS-CoV-2, influenza, and RSV highlights Uganda's ongoing respiratory virus burden. Seasonal patterns and recurrent outbreaks underscore the need for sustained surveillance, targeted vaccination, and pu...

» The epidemiology of SARS-CoV-2, Influenza, and Respiratory Syncytial Virus circulation among adult patients with acute respiratory illness in Kampala Metropolitan Area in Uganda
20/05/26 20:00 from sars-cov-2
CONCLUSION: The co-circulation of SARS-CoV-2, influenza, and RSV highlights Uganda's ongoing respiratory virus burden. Seasonal patterns and recurrent outbreaks underscore the need for sustained surveillance, targeted vaccination, and pu...

» Barriers to help-seeking for cancer in India: A scoping review
20/05/26 20:00 from coronavirus
Background and objectives Cancer is a leading cause of death in India, with delays in diagnosis and treatment contributing to poor outcomes. Although several studies document these delays, most focus on single cancer types or specific re...

» Barriers to help-seeking for cancer in India: A scoping review
20/05/26 20:00 from sars-cov-2
Background and objectives Cancer is a leading cause of death in India, with delays in diagnosis and treatment contributing to poor outcomes. Although several studies document these delays, most focus on single cancer types or specific re...

» Serum Virus-Neutralizing Antibody Titers in Clinical Trial Participants With and Without Immunocompromise Receiving Pemivibart, a Long-Acting Monoclonal Antibody for COVID-19
20/05/26 20:00 from sars-cov-2
CONCLUSIONS: These data show that previous immune experience to earlier pandemic variants provided limited cross-protection and demonstrate that pemivibart increased protective titers against newly circulating SARS-CoV-2 in individuals w...

» Equities and Inequities Inherent in Wastewater Surveillance Systems for Public Health: New York State, 2020-2024
20/05/26 20:00 from covid-19
Objectives. To evaluate equity in wastewater-based infectious disease surveillance, including equity of inclusion, outbreak detection, and disease forecasting. Methods. We assessed New York State's wastewater surveillance network using c...

» Virologist accused of starting COVID-19 fights funding ban
20/05/26 20:00 from covid-19
United States seeks to debar Ralph Baric for misleading NIAID on old coronavirus studies, which he disputes.

» The epidemiology of SARS-CoV-2, Influenza, and Respiratory Syncytial Virus circulation among adult patients with acute respiratory illness in Kampala Metropolitan Area in Uganda
20/05/26 20:00 from covid-19
CONCLUSION: The co-circulation of SARS-CoV-2, influenza, and RSV highlights Uganda's ongoing respiratory virus burden. Seasonal patterns and recurrent outbreaks underscore the need for sustained surveillance, targeted vaccination, and pu...

» Retraction: SARS-CoV2 mRNA vaccine intravenous administration induces myocarditis in chronic inflammation
20/05/26 20:00 from covid-19
No abstract

» Correction: Suicide and self-harm in low- and middle- income countries during the COVID-19 pandemic: A systematic review
20/05/26 20:00 from covid-19
[This corrects the article DOI: 10.1371/journal.pgph.0000282.].

» Retraction: Food insecurity and mental health of women during COVID-19: Evidence from a developing country
20/05/26 20:00 from covid-19
No abstract

» Addressing the silent epidemic: a narrative review and evidence synthesis of digital health and telehealth interventions for loneliness in older adults
20/05/26 20:00 from covid-19
CONCLUSIONS: Digital health and telehealth interventions hold considerable promise for mitigating loneliness among older adults. However, their benefits cannot be realized without systematically addressing the digital divide. Large-scale...

» Regenerating smell in neurodegenerative disease -translating theory into therapy
20/05/26 20:00 from covid-19
CONCLUSION: Post COVID-19 olfactory impairment has provided insights into mechanisms of smell loss and therapeutic strategies. While olfactory training remains the best studied intervention, its benefits are modest, inconsistent, and oft...

» Barriers to help-seeking for cancer in India: A scoping review
20/05/26 20:00 from covid-19
Background and objectives Cancer is a leading cause of death in India, with delays in diagnosis and treatment contributing to poor outcomes. Although several studies document these delays, most focus on single cancer types or specific re...

» Thermostable Bioluminescent Intercalating Dyes for Real-Time, Integrated Nucleic Acid Amplification and Detection
20/05/26 20:00 from covid-19
Integrated nucleic acid amplification and detection methods that can be conducted at the point of care are critical to advancing infectious disease diagnostics. We previously developed luciferase-intercalating dye conjugates ("LUMIDs") t...

» Evaluating the Impact of Telehealth Prenatal Care at a Federally Qualified Health Center
20/05/26 20:00 from covid-19
INTRODUCTION: During the COVID-19 pandemic, clinicians had to reimagine perinatal care. Mary's Center, a federally qualified health center, built an innovative telehealth group prenatal care (T-GPNC) program to ensure equitable and safe ...

» Serum Virus-Neutralizing Antibody Titers in Clinical Trial Participants With and Without Immunocompromise Receiving Pemivibart, a Long-Acting Monoclonal Antibody for COVID-19
20/05/26 20:00 from covid-19
CONCLUSIONS: These data show that previous immune experience to earlier pandemic variants provided limited cross-protection and demonstrate that pemivibart increased protective titers against newly circulating SARS-CoV-2 in individuals w...

» Intellectual and Physical Disability and Risk of COVID-19 Infection, Hospitalisation, and Mortality: A National Cohort of 3.7 Million Adults in Scotland
20/05/26 20:00 from covid-19
CONCLUSIONS: Both intellectual and physical disability were independently associated with increased risk across the COVID-19 disease pathway, with stronger associations observed for intellectual disability. These findings support disabil...

» Detection and complete genome characterisation of bat coronaviruses from Ghana
20/05/26 20:00 from covid-19
Alphacoronaviruses comprise human, livestock, and wildlife coronaviruses of importance, particularly to the livestock industry worldwide. Domestic livestock have the potential to serve as intermediate hosts of coronaviruses, given the co...

» The seven human coronavirus main proteases exhibit differential modulation of NF-kappaB suppression via TAB1 cleavage
20/05/26 20:00 from covid-19
The divergence in pathogenicity among human coronaviruses (HCoVs), from causing common cold to lethal pneumonia, may indicate distinct viral immune evasion strategies. However, the molecular basis of their differential immune evasion str...

» Leveraging randomized response frameworks to enhance sensitive data acquisition: implications for data regarding public health
20/05/26 20:00 from covid-19
Traditional survey methods make it difficult to collect sensitive data, as respondents provide false information or deliberately refuse to answer. The current investigation presents innovative methods utilizing multi-stage randomized res...

» Machine learning-enhanced modeling approach for optimally predicting household level food insecurity in Ethiopia during COVID-19
20/05/26 20:00 from covid-19
Food insecurity remains a critical global challenge, with low-income countries such as Ethiopia bearing a disproportionate burden. In settings where frequent data collection is limited, developing predictive models provides a cost-effect...

» Low prevalence and frequent co-detection of feline astrovirus with feline enteric coronavirus and feline bocaparvovirus in asymptomatic cats in Japan
20/05/26 20:00 from covid-19
Although feline astrovirus (FAstV) is recognized as a cause of feline gastroenteritis, the prevalence of asymptomatic infections in Japan remains unclear. We examined fecal samples from 124 domestic and 195 stray cats (n = 319) for FAstV...

» PANoptosis as a Therapeutic Target for COVID-19
20/05/26 20:00 from covid-19
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has sparked a global pandemic with extensive spread, posing a severe threat to public health due to its high mortality rate in severe cases. The continuous emergence of variant...

» Longitudinal characterization of COVID-19 across a surveillance transition in Japan: thirteen epidemic waves, 2020-2025
20/05/26 20:00 from covid-19
Long-term comparison of COVID-19 epidemic waves is challenging because surveillance systems and reporting practices change over time. In Japan, official reporting shifted repeatedly between January 2020 and December 2025, from comprehens...

» Detection and complete genome characterisation of bat coronaviruses from Ghana
20/05/26 20:00 from coronavirus
Alphacoronaviruses comprise human, livestock, and wildlife coronaviruses of importance, particularly to the livestock industry worldwide. Domestic livestock have the potential to serve as intermediate hosts of coronaviruses, given the co...

» Longitudinal evaluation of the psychometric stability of the somatic symptom scale-8 (SSS-8) in a large German general population sample
20/05/26 20:00 from covid-19
The Somatic Symptom Scale (SSS-8) is a brief 8-item tool for screening common somatic symptoms. This study is the first to examine its temporal invariance and stability across three COVID-19 pandemic time points, while also analyzing cha...

» Using an RNA binding protein to detect mRNA on lipid nanoparticles
20/05/26 20:00 from covid-19
The development of lipid nanoparticles (LNP) to deliver nucleic acid has emerged as a promising technology for vaccines and gene therapy. The efficiency of delivery relies on the ability of lipid chemistry to encapsulate the nucleic acid...

» The seven human coronavirus main proteases exhibit differential modulation of NF-kappaB suppression via TAB1 cleavage
20/05/26 20:00 from coronavirus
The divergence in pathogenicity among human coronaviruses (HCoVs), from causing common cold to lethal pneumonia, may indicate distinct viral immune evasion strategies. However, the molecular basis of their differential immune evasion str...

» The role of naturally occurring and vaccine-induced Ad26 neutralizing antibodies in immunogenicity of Ad26-based vaccines
20/05/26 20:00 from covid-19
Adenovirus 26 (Ad26) is frequently used as a vaccine vector targeting infectious diseases. Neutralizing antibodies (NAbs) induced by natural infection or immunization against some viral vaccine vectors may impact vaccine-induced immunoge...

» Low prevalence and frequent co-detection of feline astrovirus with feline enteric coronavirus and feline bocaparvovirus in asymptomatic cats in Japan
20/05/26 20:00 from coronavirus
Although feline astrovirus (FAstV) is recognized as a cause of feline gastroenteritis, the prevalence of asymptomatic infections in Japan remains unclear. We examined fecal samples from 124 domestic and 195 stray cats (n = 319) for FAstV...

» Long-term cross-variant Fc-mediated immune responses against SARS-CoV-2 induced by a heterologous adenoviral/inactivated virus prime-boost vaccination strategy
20/05/26 20:00 from covid-19
Limited vaccine availability and logistical barriers during the COVID-19 pandemic have hindered homologous boosting in resource-limited regions. Therefore, heterologous prime-boost regimens have gained attention as versatile and practica...

» PANoptosis as a Therapeutic Target for COVID-19
20/05/26 20:00 from coronavirus
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has sparked a global pandemic with extensive spread, posing a severe threat to public health due to its high mortality rate in severe cases. The continuous emergence of variant...

» Quantifying crowding-ventilation effect on respiratory infections
20/05/26 20:00 from covid-19
Crowded and poorly ventilated indoor spaces drive outbreaks of respiratory infections such as coronavirus disease 2019 (COVID-19), often leading to superspreading events. While overcrowding heightens risk, its interplay with space size a...

» Longitudinal evaluation of the psychometric stability of the somatic symptom scale-8 (SSS-8) in a large German general population sample
20/05/26 20:00 from coronavirus
The Somatic Symptom Scale (SSS-8) is a brief 8-item tool for screening common somatic symptoms. This study is the first to examine its temporal invariance and stability across three COVID-19 pandemic time points, while also analyzing cha...

» Temporal Association Between COVID-19 Vaccination and HBsAg Loss in Chronic Hepatitis B Infection: An Interrupted Time Series Analysis
20/05/26 20:00 from covid-19
CONCLUSION: COVID-19 vaccination was temporally associated with transiently higher HBsAg loss rates in CHB, followed by attenuation, suggesting a potential population-level immunomodulatory effect on HBV dynamics.

» Quantifying crowding-ventilation effect on respiratory infections
20/05/26 20:00 from coronavirus
Crowded and poorly ventilated indoor spaces drive outbreaks of respiratory infections such as coronavirus disease 2019 (COVID-19), often leading to superspreading events. While overcrowding heightens risk, its interplay with space size a...

» Structure activity relationship-guided scaffold hopping for identification of novel thiadiazole derivatives as potent SARS-CoV-2 Mpro inhibitors
20/05/26 20:00 from covid-19
The ongoing COVID-19 pandemic has presented enormous challenges to worldwide healthcare systems, and effective therapeutic strategies must accompany mass vaccination efforts. In this context, Mpro (the main protease of SARS-CoV-2) is arg...

» Impact of COVID-19-related data drift on machine-learning prognostic models predicting 30-day opioid-related emergency department visits, hospitalisation or mortality: a population-level administrative data study in Alberta, Canada
20/05/26 20:00 from coronavirus
CONCLUSION: COVID-19 pandemic health data contributed to significant ML drift. Although ML approaches allow for quick re-training to mitigate drift, health regulators should approach ML prediction with caution when using pandemic-times d...

» Symptomatology of SARS-CoV-2 versus seasonal coronavirus infection in healthy young children
20/05/26 20:00 from coronavirus
CONCLUSION: SARS-CoV-2 resembles other hCoVs in symptoms and severity. Cross-protection from heterotypic coronaviruses may depend on order of infections.

» Distinct age-dependent phenotypes of abnormal liver function tests derived from national Emergency Department data
20/05/26 20:00 from coronavirus
CONCLUSION: The ED presentation of abnormal LFTs results demonstrated distinct age-dependent phenotypes with divergent temporal pathogen associations. Pediatric cases reflected acute respiratory viral infections, whereas adult presentati...

» Severe Acute Respiratory Syndrome Coronavirus-2 Infection and New Changes in Thyroid Function Parameters during Hospitalization and Follow-up
20/05/26 20:00 from coronavirus
Severe acute respiratory syndrome coronavirus-2 infection is a systemic disease associated with metabolic and hormonal disturbances, including thyroid dysfunction such as primary hypothyroidism, subacute thyroiditis, and non-thyroidal il...

» Detection and complete genome characterisation of bat coronaviruses from Ghana
20/05/26 20:00 from covid-19 and viral infections in pigs
Alphacoronaviruses comprise human, livestock, and wildlife coronaviruses of importance, particularly to the livestock industry worldwide. Domestic livestock have the potential to serve as intermediate hosts of coronaviruses, given the co...

» Intellectual and Physical Disability and Risk of COVID-19 Infection, Hospitalisation, and Mortality: A National Cohort of 3.7 Million Adults in Scotland
20/05/26 20:00 from sars-cov-2
CONCLUSIONS: Both intellectual and physical disability were independently associated with increased risk across the COVID-19 disease pathway, with stronger associations observed for intellectual disability. These findings support disabil...

» The seven human coronavirus main proteases exhibit differential modulation of NF-κB suppression via TAB1 cleavage
20/05/26 20:00 from sars-cov-2
The divergence in pathogenicity among human coronaviruses (HCoVs), from causing common cold to lethal pneumonia, may indicate distinct viral immune evasion strategies. However, the molecular basis of their differential immune evasion str...

» PANoptosis as a Therapeutic Target for COVID-19
20/05/26 20:00 from sars-cov-2
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has sparked a global pandemic with extensive spread, posing a severe threat to public health due to its high mortality rate in severe cases. The continuous emergence of variant...

» Longitudinal characterization of COVID-19 across a surveillance transition in Japan: thirteen epidemic waves, 2020-2025
20/05/26 20:00 from sars-cov-2
Long-term comparison of COVID-19 epidemic waves is challenging because surveillance systems and reporting practices change over time. In Japan, official reporting shifted repeatedly between January 2020 and December 2025, from comprehens...

» Longitudinal evaluation of the psychometric stability of the somatic symptom scale-8 (SSS-8) in a large German general population sample
20/05/26 20:00 from sars-cov-2
The Somatic Symptom Scale (SSS-8) is a brief 8-item tool for screening common somatic symptoms. This study is the first to examine its temporal invariance and stability across three COVID-19 pandemic time points, while also analyzing cha...

» Long-term cross-variant Fc-mediated immune responses against SARS-CoV-2 induced by a heterologous adenoviral/inactivated virus prime-boost vaccination strategy
20/05/26 20:00 from sars-cov-2
Limited vaccine availability and logistical barriers during the COVID-19 pandemic have hindered homologous boosting in resource-limited regions. Therefore, heterologous prime-boost regimens have gained attention as versatile and practica...

» Structure activity relationship-guided scaffold hopping for identification of novel thiadiazole derivatives as potent SARS-CoV-2 Mpro inhibitors
20/05/26 20:00 from sars-cov-2
The ongoing COVID-19 pandemic has presented enormous challenges to worldwide healthcare systems, and effective therapeutic strategies must accompany mass vaccination efforts. In this context, Mpro (the main protease of SARS-CoV-2) is arg...

» Impact of COVID-19-related data drift on machine-learning prognostic models predicting 30-day opioid-related emergency department visits, hospitalisation or mortality: a population-level administrative data study in Alberta, Canada
20/05/26 20:00 from sars-cov-2
CONCLUSION: COVID-19 pandemic health data contributed to significant ML drift. Although ML approaches allow for quick re-training to mitigate drift, health regulators should approach ML prediction with caution when using pandemic-times d...

» Symptomatology of SARS-CoV-2 versus seasonal coronavirus infection in healthy young children
20/05/26 20:00 from sars-cov-2
CONCLUSION: SARS-CoV-2 resembles other hCoVs in symptoms and severity. Cross-protection from heterotypic coronaviruses may depend on order of infections.

» The epidemiology of SARS-CoV-2, Influenza, and Respiratory Syncytial Virus circulation among adult patients with acute respiratory illness in Kampala Metropolitan Area in Uganda
20/05/26 20:00 from sars-cov-2
CONCLUSION: The co-circulation of SARS-CoV-2, influenza, and RSV highlights Uganda's ongoing respiratory virus burden. Seasonal patterns and recurrent outbreaks underscore the need for sustained surveillance, targeted vaccination, and pu...

» Intellectual and Physical Disability and Risk of COVID-19 Infection, Hospitalisation, and Mortality: A National Cohort of 3.7 Million Adults in Scotland
20/05/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: Both intellectual and physical disability were independently associated with increased risk across the COVID-19 disease pathway, with stronger associations observed for intellectual disability. These findings support disabil...

» Longitudinal characterization of COVID-19 across a surveillance transition in Japan: thirteen epidemic waves, 2020-2025
20/05/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
Long-term comparison of COVID-19 epidemic waves is challenging because surveillance systems and reporting practices change over time. In Japan, official reporting shifted repeatedly between January 2020 and December 2025, from comprehens...

» Intellectual and Physical Disability and Risk of COVID-19 Infection, Hospitalisation, and Mortality: A National Cohort of 3.7 Million Adults in Scotland
20/05/26 20:00 from sars-cov-2
CONCLUSIONS: Both intellectual and physical disability were independently associated with increased risk across the COVID-19 disease pathway, with stronger associations observed for intellectual disability. These findings support disabil...

» Intellectual and Physical Disability and Risk of COVID-19 Infection, Hospitalisation, and Mortality: A National Cohort of 3.7 Million Adults in Scotland
20/05/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: Both intellectual and physical disability were independently associated with increased risk across the COVID-19 disease pathway, with stronger associations observed for intellectual disability. These findings support disabil...

» Long-term cross-variant Fc-mediated immune responses against SARS-CoV-2 induced by a heterologous adenoviral/inactivated virus prime-boost vaccination strategy
20/05/26 20:00 from sars-cov-2
Limited vaccine availability and logistical barriers during the COVID-19 pandemic have hindered homologous boosting in resource-limited regions. Therefore, heterologous prime-boost regimens have gained attention as versatile and practica...

» Impact of COVID-19-related data drift on machine-learning prognostic models predicting 30-day opioid-related emergency department visits, hospitalisation or mortality: a population-level administrative data study in Alberta, Canada
20/05/26 20:00 from sars-cov-2
CONCLUSION: COVID-19 pandemic health data contributed to significant ML drift. Although ML approaches allow for quick re-training to mitigate drift, health regulators should approach ML prediction with caution when using pandemic-times d...

» Low prevalence and frequent co-detection of feline astrovirus with feline enteric coronavirus and feline bocaparvovirus in asymptomatic cats in Japan
20/05/26 20:00 from coronavirus
Although feline astrovirus (FAstV) is recognized as a cause of feline gastroenteritis, the prevalence of asymptomatic infections in Japan remains unclear. We examined fecal samples from 124 domestic and 195 stray cats (n = 319) for FAstV...

» The epidemiology of SARS-CoV-2, Influenza, and Respiratory Syncytial Virus circulation among adult patients with acute respiratory illness in Kampala Metropolitan Area in Uganda
20/05/26 20:00 from sars-cov-2
CONCLUSION: The co-circulation of SARS-CoV-2, influenza, and RSV highlights Uganda's ongoing respiratory virus burden. Seasonal patterns and recurrent outbreaks underscore the need for sustained surveillance, targeted vaccination, and pu...