» Genome Sequencing in Infectious Disease Outbreaks
02/05/26 20:00 from coronavirus
Genome sequencing has become a crucial tool in the management and understanding of infectious disease outbreaks. By decoding the entire genetic material of pathogens, this technology allows scientists to track the spread and evolution of...

» SARS-CoV-2 spike protein exerts an anti-cancer effect in A549 cells in association with MEG3 and BCYRN1 regulation
02/05/26 20:00 from sars-cov-2 spike protein
Few studies have reported that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein may suppress cancer cell growth. Here, we investigated the effect of the SARS-CoV-2 spike protein in A549 lung cancer cells using r...

» Trends in socio-demographic disparities in COVID-19 vaccine uptake by vaccine dose and time after the introduction of COVID-19 vaccination in Israel: epidemiological and policy analysis study
02/05/26 20:00 from covid-19
CONCLUSIONS: Persistent disparities in COVID-19 vaccine uptake widened during the booster phase in Israel. While rapid, centralized rollout achieved high initial coverage, sustaining equitable uptake proved challenging. These findings hi...

» SARS-CoV-2 spike protein exerts an anti-cancer effect in A549 cells in association with MEG3 and BCYRN1 regulation
02/05/26 20:00 from coronavirus
Few studies have reported that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein may suppress cancer cell growth. Here, we investigated the effect of the SARS-CoV-2 spike protein in A549 lung cancer cells using r...

» Influenza vaccine hesitancy versus uptake in seven Chinese megacities: a cross-sectional survey
02/05/26 20:00 from covid-19
CONCLUSIONS: Influenza vaccination in Chinese megacities is driven by a mix of demographic, psychosocial, and behavioural factors. Targeted strategies addressing both hesitancy and uptake are needed to improve coverage and reduce influen...

» Targeting the Elongin BC-BC-Box Interface: Structural Insights, Peptidic Disruptors and Emerging Small-Molecule Strategies
02/05/26 20:00 from coronavirus
Protein-protein interactions (PPIs) that orchestrate ubiquitin-dependent signaling have long challenged drug discovery because their interfaces are typically large and hydrophobic. The heterodimeric adaptor Elongin BC (ELOB/ELOC) defies ...

» Nurse and Patient Outcomes in Private and Public Hospitals in South Africa During the COVID-19 Pandemic: A Cross-Sectional Study
02/05/26 20:00 from covid-19
CONCLUSION: Interventions to improve nurse wellbeing and retention as well as quality and safety of care should focus on improving hospital practice environments, specifically nurse manager expertise, nurse leadership, nurse participatio...

» Masturbation as a sexual and psychological coping strategy in long-distance relationships: a systematic review
02/05/26 20:00 from coronavirus
CONCLUSION: Masturbation appears to be a common and potentially adaptive alternative sexual activity in the context of LDRs and during the COVID-19 pandemic. However, in Eastern contexts, its meaning and impact are strongly shaped by soc...

» Genome Sequencing in Infectious Disease Outbreaks
02/05/26 20:00 from covid-19
Genome sequencing has become a crucial tool in the management and understanding of infectious disease outbreaks. By decoding the entire genetic material of pathogens, this technology allows scientists to track the spread and evolution of...

» Acute SARS-CoV-2 infection and self-reported post-acute cognitive dysfunctions from the Danish EFTER-COVID survey
02/05/26 20:00 from covid-19
CONCLUSION: In the general population of SARS-CoV-2 infected individuals, self-reported post-acute scores of cognitive dysfunctions are low and only slightly higher than corresponding scores among test-negatives. Higher COBRA scores amon...

» SARS-CoV-2 spike protein exerts an anti-cancer effect in A549 cells in association with MEG3 and BCYRN1 regulation
02/05/26 20:00 from covid-19
Few studies have reported that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein may suppress cancer cell growth. Here, we investigated the effect of the SARS-CoV-2 spike protein in A549 lung cancer cells using r...

» Parent-Reported Influenza Vaccination Uptake, Hesitancy and Willingness for In-School Children: Survey Findings From Shenzhen, China With Free Vaccination Services
02/05/26 20:00 from covid-19
CONCLUSIONS: Our study suggests that there is considerable room for Chinese parents to increase the uptake of influenza vaccination and eliminate vaccine hesitancy for in-school children. Multi-aspect efforts are needed to increase paren...

» Targeting the Elongin BC-BC-Box Interface: Structural Insights, Peptidic Disruptors and Emerging Small-Molecule Strategies
02/05/26 20:00 from covid-19
Protein-protein interactions (PPIs) that orchestrate ubiquitin-dependent signaling have long challenged drug discovery because their interfaces are typically large and hydrophobic. The heterodimeric adaptor Elongin BC (ELOB/ELOC) defies ...

» Bidirectional relations between avoidant coping and dependent stressors in college students
02/05/26 20:00 from covid-19
CONCLUSION: Avoidant coping is associated with stressor generation across individuals and within individuals over time. Resources that help reduce avoidant coping may also reduce experiences of dependent stressors.

» Evaluation of the QuickFinder COVID-19/Flu/RSV antigen test for rapid simultaneous detection of SARS-CoV-2, influenza A/B viruses, and respiratory syncytial virus
02/05/26 20:00 from covid-19
Antigen rapid diagnostic tests (Ag-RDTs) offer faster turnaround times and greater accessibility than molecular assays, making them practical tools for the early diagnosis of respiratory infections. This study evaluated the performance o...

» The mediating role of life skills in the association of the coach-athlete relationship with youth athletes' well-being
02/05/26 20:00 from covid-19
The coach-athlete relationship is central for the development and well-being of adolescent athletes, but the mechanisms underlying this relation are underexplored. Learning life skills may explain these underlying mechanisms; therefore, ...

» Masturbation as a sexual and psychological coping strategy in long-distance relationships: a systematic review
02/05/26 20:00 from covid-19
CONCLUSION: Masturbation appears to be a common and potentially adaptive alternative sexual activity in the context of LDRs and during the COVID-19 pandemic. However, in Eastern contexts, its meaning and impact are strongly shaped by soc...

» Evaluation of the QuickFinder COVID-19/Flu/RSV antigen test for rapid simultaneous detection of SARS-CoV-2, influenza A/B viruses, and respiratory syncytial virus
02/05/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
Antigen rapid diagnostic tests (Ag-RDTs) offer faster turnaround times and greater accessibility than molecular assays, making them practical tools for the early diagnosis of respiratory infections. This study evaluated the performance o...

» Genome Sequencing in Infectious Disease Outbreaks
02/05/26 20:00 from sars-cov-2
Genome sequencing has become a crucial tool in the management and understanding of infectious disease outbreaks. By decoding the entire genetic material of pathogens, this technology allows scientists to track the spread and evolution of...

» Acute SARS-CoV-2 infection and self-reported post-acute cognitive dysfunctions from the Danish EFTER-COVID survey
02/05/26 20:00 from sars-cov-2
CONCLUSION: In the general population of SARS-CoV-2 infected individuals, self-reported post-acute scores of cognitive dysfunctions are low and only slightly higher than corresponding scores among test-negatives. Higher COBRA scores amon...

» SARS-CoV-2 spike protein exerts an anti-cancer effect in A549 cells in association with MEG3 and BCYRN1 regulation
02/05/26 20:00 from sars-cov-2
Few studies have reported that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein may suppress cancer cell growth. Here, we investigated the effect of the SARS-CoV-2 spike protein in A549 lung cancer cells using r...

» Targeting the Elongin BC-BC-Box Interface: Structural Insights, Peptidic Disruptors and Emerging Small-Molecule Strategies
02/05/26 20:00 from sars-cov-2
Protein-protein interactions (PPIs) that orchestrate ubiquitin-dependent signaling have long challenged drug discovery because their interfaces are typically large and hydrophobic. The heterodimeric adaptor Elongin BC (ELOB/ELOC) defies ...

» Evaluation of the QuickFinder COVID-19/Flu/RSV antigen test for rapid simultaneous detection of SARS-CoV-2, influenza A/B viruses, and respiratory syncytial virus
02/05/26 20:00 from sars-cov-2
Antigen rapid diagnostic tests (Ag-RDTs) offer faster turnaround times and greater accessibility than molecular assays, making them practical tools for the early diagnosis of respiratory infections. This study evaluated the performance o...

» Masturbation as a sexual and psychological coping strategy in long-distance relationships: a systematic review
02/05/26 20:00 from sars-cov-2
CONCLUSION: Masturbation appears to be a common and potentially adaptive alternative sexual activity in the context of LDRs and during the COVID-19 pandemic. However, in Eastern contexts, its meaning and impact are strongly shaped by soc...

» Preterm Birth and Perinatal Mortality During the COVID-19 Pandemic Period: A Systematic Review and Meta-Analysis
01/05/26 20:00 from coronavirus
CONCLUSION: The COVID-19 pandemic was associated with a reduction in preterm births and neonatal deaths. Further research is needed to investigate the mechanisms underlying these findings. Stillbirth rates increased in low- and middle-in...

» Preterm Birth and Perinatal Mortality During the COVID-19 Pandemic Period: A Systematic Review and Meta-Analysis
01/05/26 20:00 from covid-19
CONCLUSION: The COVID-19 pandemic was associated with a reduction in preterm births and neonatal deaths. Further research is needed to investigate the mechanisms underlying these findings. Stillbirth rates increased in low- and middle-in...

» Preterm Birth and Perinatal Mortality During the COVID-19 Pandemic Period: A Systematic Review and Meta-Analysis
01/05/26 20:00 from sars-cov-2
CONCLUSION: The COVID-19 pandemic was associated with a reduction in preterm births and neonatal deaths. Further research is needed to investigate the mechanisms underlying these findings. Stillbirth rates increased in low- and middle-in...

» Statistical crystallography reveals an allosteric network in SARS-CoV-2 M^pro
01/05/26 20:00 from coronavirus
To interpret and transmit biological signals, proteins use correlated motions. Experimental determination of these dynamics and the structural distributions they generate remains a key challenge. Here, using 1146 crystal structures of th...

» Nanomedicine-based theranostics in atherosclerotic cardiovascular diseases
01/05/26 20:00 from coronavirus
Current treatment for atherosclerotic cardiovascular diseases (ASCVD) mainly focuses on the modification of systemic risk factors, such as hyperglycemia and hyperlipidemia. Despite significant efforts and expanse, achieving early and pro...

» Pediatric SARS-CoV-2 outcomes study (PECOS): 12-month longitudinal analysis of post-COVID symptoms in infected versus uninfected participants
01/05/26 20:00 from sars-cov-2
CONCLUSIONS: Interim analysis at one-year post-enrollment identifies 20 symptoms that infected participants were more likely to report post SARS-CoV-2 infection compared to uninfected, at either visit. Type of symptoms varies by age. Ong...

» THE DYNAMICS OF PERCEPTIONS AND EVALUATION OF THE COMPONENTS OF THE IMAGE OF AN IDEAL TEACHER DURING THE COVID-19 PANDEMIC
01/05/26 20:00 from coronavirus
A renewed reforming of the higher education system is taking place in the conditions of the Covid-19 pandemic, as well as the perception of the essence and content of the pedagogical profession is changing in the changing conditions of t...

» COGNITIVE RESERVE IN PATIENTS AFTER CORONAVIRUS INFECTION
01/05/26 20:00 from coronavirus
CONCLUSIONS: Post-COVID cognitive impairment occurs despite preserved premorbid cognitive reserve and is characterized by reduced utilization and engagement of reserve mechanisms, particularly following severe disease.

» Molecular insights into domestic cat hepatitis B virus linking genome to function
01/05/26 20:00 from coronavirus
Domestic cat hepatitis B virus (DCHBV) is a member of the Hepadnaviridae family and has been associated with hepatocellular carcinoma (HCC) in cats. This study aimed to determine the prevalence of DCHBV and associations with feline immun...

» Surrogate virus neutralization test as a scalable and reliable tool for immune surveillance in booster-vaccinated populations
01/05/26 20:00 from sars-cov-2
With waning vaccine-induced immunity and the continued emergence of immune-evasive SARS-CoV-2 variants, booster vaccination has become essential for sustaining population-level protection. However, scalable and reliable serological tools...

» Pediatric SARS-CoV-2 outcomes study (PECOS): 12-month longitudinal analysis of post-COVID symptoms in infected versus uninfected participants
01/05/26 20:00 from covid-19
CONCLUSIONS: Interim analysis at one-year post-enrollment identifies 20 symptoms that infected participants were more likely to report post SARS-CoV-2 infection compared to uninfected, at either visit. Type of symptoms varies by age. Ong...

» Statistical crystallography reveals an allosteric network in SARS-CoV-2 M(pro)
01/05/26 20:00 from sars-cov-2
To interpret and transmit biological signals, proteins use correlated motions. Experimental determination of these dynamics and the structural distributions they generate remains a key challenge. Here, using 1146 crystal structures of th...

» A TRAC-478-adjuvanted recombinant N1 neuraminidase influenza virus vaccine induces balanced and broadly protective immune responses
01/05/26 20:00 from sars-cov-2
Licensed influenza vaccines primarily target the variable hemagglutinin protein and provide inadequate cross-protection against mismatched or drifted viral strains. One promising approach to enhance the breadth of protection is to target...

» Surrogate virus neutralization test as a scalable and reliable tool for immune surveillance in booster-vaccinated populations
01/05/26 20:00 from covid-19
With waning vaccine-induced immunity and the continued emergence of immune-evasive SARS-CoV-2 variants, booster vaccination has become essential for sustaining population-level protection. However, scalable and reliable serological tools...

» Impact of online gambling on youth problem behaviors during COVID-19 periods in South Korea
01/05/26 20:00 from covid-19
This study investigates the impact of online gambling on problem behaviors among South Korean adolescents across three phases of the COVID-19 pandemic: pre-pandemic (2018), early pandemic (2020), and late pandemic (2022). We applied a do...

» Heterogeneous estimations of non-pharmaceutical mitigation behavior during the COVID-19 pandemic
01/05/26 20:00 from sars-cov-2
The COVID-19 pandemic highlighted the importance of human behavior in mitigating the spread of disease. Nonetheless, human behavior is often overlooked in models of disease spread, particularly by underutilizing real-world data. We addre...

» Fifteen-year trends in cancer incidence and mortality among older adults aged 65 years and older in Martinique, a Caribbean population-based registry study, 2008-2022
01/05/26 20:00 from covid-19
Prostate, breast, stomach, colon-rectum, lung, and hematologic cancers represent a regional public health burden among older adults in the Caribbean. We described 15-year trends in cancer incidence and mortality among older adults in Mar...

» Statistical crystallography reveals an allosteric network in SARS-CoV-2 M(pro)
01/05/26 20:00 from covid-19
To interpret and transmit biological signals, proteins use correlated motions. Experimental determination of these dynamics and the structural distributions they generate remains a key challenge. Here, using 1146 crystal structures of th...

» A pan-viral map of host dependency factors from multi-omics integration and machine learning across influenza A, SARS-CoV-2, Zika, and dengue viruses
01/05/26 20:00 from sars-cov-2
CONCLUSIONS: Our integrative multi-omics and machine-learning approach outlines a prediction-based, data-driven map of pan-viral host liabilities and highlights tractable opportunities for host-directed therapy against diverse RNA viruses.

» COVID-19 disruptions and spring surges: an interrupted time-series analysis of tuberculosis diagnostic challenges in Northeast Iran
01/05/26 20:00 from covid-19
Tuberculosis (TB) remains a significant public health challenge in Northeast Iran, yet longitudinal data evaluating regional transmission patterns following COVID-19 disruptions remain limited. This cross-sectional study, conducted from ...

» A TRAC-478-adjuvanted recombinant N1 neuraminidase influenza virus vaccine induces balanced and broadly protective immune responses
01/05/26 20:00 from covid-19
Licensed influenza vaccines primarily target the variable hemagglutinin protein and provide inadequate cross-protection against mismatched or drifted viral strains. One promising approach to enhance the breadth of protection is to target...

» Heterogeneous estimations of non-pharmaceutical mitigation behavior during the COVID-19 pandemic
01/05/26 20:00 from covid-19
The COVID-19 pandemic highlighted the importance of human behavior in mitigating the spread of disease. Nonetheless, human behavior is often overlooked in models of disease spread, particularly by underutilizing real-world data. We addre...

» Psychophysiological effects of dance/movement therapy on anxiety reduction in adolescents in juvenile detention centers: dopamine and thermoregulatory responses in a controlled study
01/05/26 20:00 from covid-19
CONCLUSIONS: This study provides preliminary evidence that DMT may help alleviate anxiety and support psychophysiological regulation among adolescents in JDCs. However, the exploratory design, single-center setting, and all-female sample...

» Optimizing Georgia's public health workforce: a study on demographics, engagement, and capacity building
01/05/26 20:00 from covid-19
CONCLUSIONS: These findings are pivotal in identifying workforce planning and development bottlenecks and developing targeted strategies. Key interventions include addressing an aging workforce through targeted recruitment and succession...

» A pan-viral map of host dependency factors from multi-omics integration and machine learning across influenza A, SARS-CoV-2, Zika, and dengue viruses
01/05/26 20:00 from covid-19
CONCLUSIONS: Our integrative multi-omics and machine-learning approach outlines a prediction-based, data-driven map of pan-viral host liabilities and highlights tractable opportunities for host-directed therapy against diverse RNA viruses.

» Nanomedicine-based theranostics in atherosclerotic cardiovascular diseases
01/05/26 20:00 from covid-19
Current treatment for atherosclerotic cardiovascular diseases (ASCVD) mainly focuses on the modification of systemic risk factors, such as hyperglycemia and hyperlipidemia. Despite significant efforts and expanse, achieving early and pro...

» Rising trend among young adults: analysis of suicide-related deaths in Türkiye 2007-2022
01/05/26 20:00 from covid-19
CONCLUSIONS: It has been shown that suicide-related deaths in young adults in Türkiye are increasing. The fact that the increase especially in women is significantly high requires health authorities to take steps in this field.

» Extending Tanner's framework: the digital clinical judgment model for nursing education
01/05/26 20:00 from covid-19
CONCLUSION: As a conceptually grounded pedagogical model, the DCJM offers educators a theoretically informed and practically applicable framework for designing learning environments that support the development of clinical judgment in co...

» Nanomedicine-based theranostics in atherosclerotic cardiovascular diseases
01/05/26 20:00 from sars-cov-2
Current treatment for atherosclerotic cardiovascular diseases (ASCVD) mainly focuses on the modification of systemic risk factors, such as hyperglycemia and hyperlipidemia. Despite significant efforts and expanse, achieving early and pro...

» THE DYNAMICS OF PERCEPTIONS AND EVALUATION OF THE COMPONENTS OF THE IMAGE OF AN IDEAL TEACHER DURING THE COVID-19 PANDEMIC
01/05/26 20:00 from covid-19
A renewed reforming of the higher education system is taking place in the conditions of the Covid-19 pandemic, as well as the perception of the essence and content of the pedagogical profession is changing in the changing conditions of t...

» A pan-viral map of host dependency factors from multi-omics integration and machine learning across influenza A, SARS-CoV-2, Zika, and dengue viruses
01/05/26 20:00 from Cell entry mechanisms of SARS-CoV-2
CONCLUSIONS: Our integrative multi-omics and machine-learning approach outlines a prediction-based, data-driven map of pan-viral host liabilities and highlights tractable opportunities for host-directed therapy against diverse RNA viruses.

» THE DYNAMICS OF PERCEPTIONS AND EVALUATION OF THE COMPONENTS OF THE IMAGE OF AN IDEAL TEACHER DURING THE COVID-19 PANDEMIC
01/05/26 20:00 from sars-cov-2
A renewed reforming of the higher education system is taking place in the conditions of the Covid-19 pandemic, as well as the perception of the essence and content of the pedagogical profession is changing in the changing conditions of t...

» COGNITIVE RESERVE IN PATIENTS AFTER CORONAVIRUS INFECTION
01/05/26 20:00 from sars-cov-2
CONCLUSIONS: Post-COVID cognitive impairment occurs despite preserved premorbid cognitive reserve and is characterized by reduced utilization and engagement of reserve mechanisms, particularly following severe disease.

» COVID-19 Hospitalisations in women of childbearing age and children during the Omicron period, January 2023 to September 2024
01/05/26 20:00 from sars-cov-2
CONCLUSIONS: Rates of severe COVID-19 were low. National databases for SARS-CoV-2 surveillance need to capture disease activity more accurately.

» Analytical performance of the AMDI™ Fast PCR Mini Respiratory Panel
01/05/26 20:00 from sars-cov-2
Influenza A, Influenza B, SARS-CoV-2, Respiratory Syncytial Virus and other respiratory pathogens are an ongoing public health concern. Rapid identification of these viruses early in infection is essential for effective treatment and out...

» Pediatric SARS-CoV-2 outcomes study (PECOS): 12-month longitudinal analysis of post-COVID symptoms in infected versus uninfected participants
01/05/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: Interim analysis at one-year post-enrollment identifies 20 symptoms that infected participants were more likely to report post SARS-CoV-2 infection compared to uninfected, at either visit. Type of symptoms varies by age. Ong...

» THE DYNAMICS OF PERCEPTIONS AND EVALUATION OF THE COMPONENTS OF THE IMAGE OF AN IDEAL TEACHER DURING THE COVID-19 PANDEMIC
01/05/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
A renewed reforming of the higher education system is taking place in the conditions of the Covid-19 pandemic, as well as the perception of the essence and content of the pedagogical profession is changing in the changing conditions of t...

» COVID-19 Hospitalisations in women of childbearing age and children during the Omicron period, January 2023 to September 2024
01/05/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: Rates of severe COVID-19 were low. National databases for SARS-CoV-2 surveillance need to capture disease activity more accurately.

» Broad-spectrum CRISPR-Cas13d-mediated strategy for combating human coronaviruses
30/04/26 20:00 from coronavirus
RNA viruses evolve rapidly, enabling them to evade host immunity and antiviral therapies and complicating durable diagnostics strategies. There is a pressing need for approaches that provide broad-spectrum viral suppression and detection...

» Prerenal acute kidney injury diagnosed by urinary indices in a COVID-19 patient: A critical care case report
30/04/26 20:00 from coronavirus
Coronavirus Disease 2019 (COVID-19) primarily affects the respiratory system but can also cause acute kidney injury (AKI). Infection-related circulatory disturbances driven by systemic inflammation, cytokine release, and reduced effectiv...

» Cross-talk between inflammation and coagulation in severe COVID-19: Association of leptin and classical pro-inflammatory markers with coagulation disorders in a single-center observational cohort study
30/04/26 20:00 from sars-cov-2
We performed a single-center observational cohort study on patients with COVID-19. We retrospectively analyzed 54 patients with confirmed SARS-CoV-2 infection, diagnosed as critically ill. Severely ill patients have a poor prognosis and ...

» Surveillance of Zoonotic Pathogens and Taxonomic Identification of Non-volant Small Mammals in Peninsular Malaysia
30/04/26 20:00 from coronavirus
Malaysia's tropical rainforests host a rich biodiversity, including various non-volant small mammals. Among these, murid rodents (family Muridae) are ecologically significant and frequently associated with zoonotic pathogens, making them...

» Effect of PEI25k/DOTAP/cholesterol liposomal formulation on the immunogenicity of SARS-CoV-2 spike protein-encoding DNA vaccine
30/04/26 20:00 from coronavirus
CONCLUSIONS: The PEI25k : DOTAP : cholesterol (2 : 1 : 1) formulation has high potential as a liposome-based adjuvant for enhancing the immunogenicity of DNA vaccines. The findings of this study support its suitability for further develo...

» Establishment of an interdisciplinary curriculum in the core dental competence of "dental traumatology"
30/04/26 20:00 from coronavirus
CONCLUSION: The interdisciplinary curriculum led to an increase in learning among the students. However, the heterogeneous results of the case vignettes show that even interdisciplinary lectures are not very efficient in acquiring the co...

» Broad-spectrum CRISPR-Cas13d-mediated strategy for combating human coronaviruses
30/04/26 20:00 from sars-cov-2
RNA viruses evolve rapidly, enabling them to evade host immunity and antiviral therapies and complicating durable diagnostics strategies. There is a pressing need for approaches that provide broad-spectrum viral suppression and detection...

» Correction: Post-vaccination SARS-CoV-2 infections and antibody responses after BNT162b2 in patients with severe obesity: a retrospective cohort study
30/04/26 20:00 from sars-cov-2
[This corrects the article DOI: 10.3389/fendo.2026.1759985.].

» Impf-Guides - experiences with a project aimed at increasing vaccination willingness in Munich during the COVID-19 pandemic
30/04/26 20:00 from coronavirus
OBJECTIVE: The project Impf-Guides aimed at motivating citizens in selected districts of Munich to get vaccinated against COVID-19 by providing information and advice, thereby increasing the vaccination rate among the population.

» Prerenal acute kidney injury diagnosed by urinary indices in a COVID-19 patient: A critical care case report
30/04/26 20:00 from sars-cov-2
Coronavirus Disease 2019 (COVID-19) primarily affects the respiratory system but can also cause acute kidney injury (AKI). Infection-related circulatory disturbances driven by systemic inflammation, cytokine release, and reduced effectiv...

» Healthcare access difficulty due to fear of COVID-19 infection among women of reproductive age: multilevel mixed-effects logistic regression analysis
30/04/26 20:00 from coronavirus
CONCLUSION: Interventions that influence routine health facility visits can boost healthcare access among women. Enumeration area-specific interventions may be more effective.

» Effect of PEI25k/DOTAP/cholesterol liposomal formulation on the immunogenicity of SARS-CoV-2 spike protein-encoding DNA vaccine
30/04/26 20:00 from sars-cov-2 spike protein
CONCLUSIONS: The PEI25k : DOTAP : cholesterol (2 : 1 : 1) formulation has high potential as a liposome-based adjuvant for enhancing the immunogenicity of DNA vaccines. The findings of this study support its suitability for further develo...

» Boesenbergia rotunda-Derived Phytochemicals as Potent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): Insights From Molecular Docking and Dynamic Simulation
30/04/26 20:00 from sars-cov-2
The papain-like protease (PLpro) of SARS-CoV-2 plays fundamental roles in its replication, and its mechanistic inhibition can impede the virus's replication and infection. Most Plpro inhibitors identified thus far are chemically synthesi...

» Gut microbial profiles of COVID-19 patients in Uganda
30/04/26 20:00 from coronavirus
CONCLUSION: The microbiome likely plays a role in the dynamics of SARS-CoV-2 infection in Ugandan patients. The shift in abundance of specific microbes can moderately predict severity of COVID-19 in this population.

» Effect of PEI25k/DOTAP/cholesterol liposomal formulation on the immunogenicity of SARS-CoV-2 spike protein-encoding DNA vaccine
30/04/26 20:00 from sars-cov-2
CONCLUSIONS: The PEI25k : DOTAP : cholesterol (2 : 1 : 1) formulation has high potential as a liposome-based adjuvant for enhancing the immunogenicity of DNA vaccines. The findings of this study support its suitability for further develo...

» A phase 1, single-center, randomized, dose finding study to evaluate the safety, tolerability, and immunogenicity of a prophylactic COVID-19 pDNA vaccine after single ascending doses in healthy adults
30/04/26 20:00 from sars-cov-2 spike protein
BACKGROUND: SARS-CoV-2 has been responsible for a worldwide public health crisis and a pandemic that began in February 2020, with approximately 679 million cases and over 6.7 million deaths to date. Despite the existence of approved COVI...

» Establishment of an interdisciplinary curriculum in the core dental competence of "dental traumatology"
30/04/26 20:00 from sars-cov-2
CONCLUSION: The interdisciplinary curriculum led to an increase in learning among the students. However, the heterogeneous results of the case vignettes show that even interdisciplinary lectures are not very efficient in acquiring the co...

» Impf-Guides - experiences with a project aimed at increasing vaccination willingness in Munich during the COVID-19 pandemic
30/04/26 20:00 from sars-cov-2
OBJECTIVE: The project Impf-Guides aimed at motivating citizens in selected districts of Munich to get vaccinated against COVID-19 by providing information and advice, thereby increasing the vaccination rate among the population.

» Real-world impact of point-of-care testing for SARS-CoV-2 in an ambulatory setting of an integrated health network
30/04/26 20:00 from sars-cov-2
CONCLUSIONS: POC molecular testing outperformed antigen testing in SARS-CoV-2 detection and was associated with lower antibiotic prescribing, supporting its role in antimicrobial stewardship.

» Trends in accidental poisoning and exposure to noxious substances involving drugs, medicaments, and biological substances-related deaths: A nationwide US analysis, 1999 to 2023
30/04/26 20:00 from covid-19
Unintentional poisoning and exposure to harmful substances involving illicit drugs, medications other than those taken as prescribed, and biological substances have emerged as a leading cause of preventable death in the United States. Th...

» Boesenbergia rotunda-Derived Phytochemicals as Potent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): Insights From Molecular Docking and Dynamic Simulation
30/04/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
The papain-like protease (PLpro) of SARS-CoV-2 plays fundamental roles in its replication, and its mechanistic inhibition can impede the virus's replication and infection. Most Plpro inhibitors identified thus far are chemically synthesi...

» Healthcare access difficulty due to fear of COVID-19 infection among women of reproductive age: multilevel mixed-effects logistic regression analysis
30/04/26 20:00 from sars-cov-2
CONCLUSION: Interventions that influence routine health facility visits can boost healthcare access among women. Enumeration area-specific interventions may be more effective.

» Gut microbial profiles of COVID-19 patients in Uganda
30/04/26 20:00 from sars-cov-2
CONCLUSION: The microbiome likely plays a role in the dynamics of SARS-CoV-2 infection in Ugandan patients. The shift in abundance of specific microbes can moderately predict severity of COVID-19 in this population.

» Cross-talk between inflammation and coagulation in severe COVID-19: Association of leptin and classical pro-inflammatory markers with coagulation disorders in a single-center observational cohort study
30/04/26 20:00 from covid-19
We performed a single-center observational cohort study on patients with COVID-19. We retrospectively analyzed 54 patients with confirmed SARS-CoV-2 infection, diagnosed as critically ill. Severely ill patients have a poor prognosis and ...

» A phase 1, single-center, randomized, dose finding study to evaluate the safety, tolerability, and immunogenicity of a prophylactic COVID-19 pDNA vaccine after single ascending doses in healthy adults
30/04/26 20:00 from sars-cov-2
BACKGROUND: SARS-CoV-2 has been responsible for a worldwide public health crisis and a pandemic that began in February 2020, with approximately 679 million cases and over 6.7 million deaths to date. Despite the existence of approved COVI...

» An open-label, clinical feasibility study of the efficacy of Remdesivir for Long-COVID
30/04/26 20:00 from sars-cov-2
BACKGROUND: Long COVID (LC) affects around two million people in the UK and over 65 million people globally. Antiviral medications have shown positive effects in reducing the risk of progression to severe disease in high-risk patients du...

» Ivermectin therapy is associated with changes in SARS-CoV-2 RNA load in asymptomatic patients: a randomized controlled trial
30/04/26 20:00 from sars-cov-2
CONCLUSION: A single oral dose of ivermectin may accelerate viral clearance and reduce symptom progression in asymptomatic SARS-CoV-2-positive individuals. Further large-scale, multi-center randomized trials are warranted to confirm thes...

» Broad-spectrum CRISPR-Cas13d-mediated strategy for combating human coronaviruses
30/04/26 20:00 from covid-19
RNA viruses evolve rapidly, enabling them to evade host immunity and antiviral therapies and complicating durable diagnostics strategies. There is a pressing need for approaches that provide broad-spectrum viral suppression and detection...

» SARS-CoV-2 intra-host viral diversity associated with host innate and vaccine-induced immunity in an obese mouse model
30/04/26 20:00 from sars-cov-2
No abstract

» The influence of the COVID-19 public health emergency and dental coverage on the utilization of endodontic treatment in the United States
30/04/26 20:00 from covid-19
CONCLUSION: The study highlights the critical role of benefit design in ensuring dental service utilization, particularly during public health emergencies. Oral health stakeholders must recognize the potential long-term consequences of d...

» Telehealth adoption and use intentions among neurologists in Saudi Arabia: a cross-sectional study
30/04/26 20:00 from covid-19
CONCLUSION: Most surveyed neurologists reported a high intention to use telehealth. Confidence in telehealth was higher for follow-up care than for new-patient consultations. Overall attitudes toward telehealth were moderately positive a...

» Correction: Post-vaccination SARS-CoV-2 infections and antibody responses after BNT162b2 in patients with severe obesity: a retrospective cohort study
30/04/26 20:00 from covid-19
[This corrects the article DOI: 10.3389/fendo.2026.1759985.].

» Prerenal acute kidney injury diagnosed by urinary indices in a COVID-19 patient: A critical care case report
30/04/26 20:00 from covid-19
Coronavirus Disease 2019 (COVID-19) primarily affects the respiratory system but can also cause acute kidney injury (AKI). Infection-related circulatory disturbances driven by systemic inflammation, cytokine release, and reduced effectiv...

» Enhancing context-aware SARS disorder management: a proposed multi-agent simulation framework with machine learning and bio-sensor data integration
30/04/26 20:00 from covid-19
In this work, SARS disorder denotes a generic acute severe respiratory distress condition characterized by abnormal respiratory rate, oxygen saturation, fever, and cardiovascular stress indicators, and does not represent a COVID-19 diagn...

» Thimble Bladder: A Forgotten Entity
30/04/26 20:00 from covid-19
Urogenital tuberculosis (TB) is uncommon in children. The kidney is the most common organ involved. With the spread of the disease along the urinary system, the bladder is affected very late in the disease. Considering the long latency p...

» Boesenbergia rotunda-Derived Phytochemicals as Potent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): Insights From Molecular Docking and Dynamic Simulation
30/04/26 20:00 from covid-19
The papain-like protease (PLpro) of SARS-CoV-2 plays fundamental roles in its replication, and its mechanistic inhibition can impede the virus's replication and infection. Most Plpro inhibitors identified thus far are chemically synthesi...

» The moderating and mediating effects of mindful compassion with body-mind-spirit therapy using a blended approach of face-to-face with online for breast cancer patients' depression during COVID-19: A randomized controlled trial
30/04/26 20:00 from covid-19
CONCLUSIONS: Both delivery formats appear feasible and may provide psychological benefits for breast cancer patients. Future research is needed to determine the optimal balance between face-to-face and online sessions and to clarify the ...

» Effect of PEI25k/DOTAP/cholesterol liposomal formulation on the immunogenicity of SARS-CoV-2 spike protein-encoding DNA vaccine
30/04/26 20:00 from covid-19
CONCLUSIONS: The PEI25k : DOTAP : cholesterol (2 : 1 : 1) formulation has high potential as a liposome-based adjuvant for enhancing the immunogenicity of DNA vaccines. The findings of this study support its suitability for further develo...

» Establishment of an interdisciplinary curriculum in the core dental competence of "dental traumatology"
30/04/26 20:00 from covid-19
CONCLUSION: The interdisciplinary curriculum led to an increase in learning among the students. However, the heterogeneous results of the case vignettes show that even interdisciplinary lectures are not very efficient in acquiring the co...

» Impf-Guides - experiences with a project aimed at increasing vaccination willingness in Munich during the COVID-19 pandemic
30/04/26 20:00 from covid-19
OBJECTIVE: The project Impf-Guides aimed at motivating citizens in selected districts of Munich to get vaccinated against COVID-19 by providing information and advice, thereby increasing the vaccination rate among the population.

» Real-world impact of point-of-care testing for SARS-CoV-2 in an ambulatory setting of an integrated health network
30/04/26 20:00 from covid-19
CONCLUSIONS: POC molecular testing outperformed antigen testing in SARS-CoV-2 detection and was associated with lower antibiotic prescribing, supporting its role in antimicrobial stewardship.

» Repurposing drug screen for the identification of helicase inhibitors from viruses of pandemic concern
30/04/26 20:00 from coronavirus
Several families of viruses encode helicase enzymes with essential roles in viral genome replication and transcription, including several RNA virus families of pandemic concern, such as coronaviruses and flaviviruses. Viral helicases are...

» Antiviral effect of lactoferrin against infectious bronchitis virus (IBV) are associated with alterations in the gastrointestinal microbiome
30/04/26 20:00 from coronavirus
Coronaviruses (CoVs) are an enveloped, polymorphic, positive-sense single-stranded RNA viruses. Currently, both humans and animals are threatened by CoVs, making them a major public health concern. Among the four genera of the family Cor...

» A Novel Covalent Inhibitor Fragment for the SARS-CoV-2 Main Protease Identified by Target-Specific Deep Learning
30/04/26 20:00 from coronavirus
The SARS-CoV-2 main protease (M^(pro), also known as 3CL^(pro)) is an attractive antiviral drug target due to its essential role in viral replication and absence of human homologues. Development of new coronavirus-specific M^(pro) inhibi...

» B cells gone broad: A deep dive into SARS-CoV-2 antibody breadth
30/04/26 20:00 from coronavirus
Antigen-specific B cell profiling uncovers key determinants of SARS-CoV-2 antibody breadth after infection and vaccination.

» Unmasking Adrenal Insufficiency in COVID-19: The Diagnostic Challenge of Concomitant Acute Kidney Injury and High Ileostomy Output
30/04/26 20:00 from coronavirus
BACKGROUND The coronavirus disease 2019 (COVID-19) pandemic has elucidated various extrapulmonary manifestations of severe acute respiratory syndrome coronavirus 2, including endocrine complications that affect the hypothalamic-pituitary...

» Enhancing translation capacities of COVID-19 researchers through interdisciplinary collaboration: empathy, awareness, and action
30/04/26 20:00 from coronavirus
PURPOSE: Integrating societal considerations into public health research, particularly during crises, can foster public trust, support inclusive policy-making, and enhance technology development. Interdisciplinary collaboration may enhan...

» Phospholipase PLA2G5-triggered hemolysis emerges as a contributor to sepsis lethality
30/04/26 20:00 from coronavirus
Despite extensive advances in understanding sepsis pathophysiology, treatment outcomes have not substantially improved. In this issue, Takahama and colleagues identified phospholipase A2 Group V (PLA2G5) as a contributor to sepsis lethal...

» Trends in accidental poisoning and exposure to noxious substances involving drugs, medicaments, and biological substances-related deaths: A nationwide US analysis, 1999 to 2023
30/04/26 20:00 from coronavirus
Unintentional poisoning and exposure to harmful substances involving illicit drugs, medications other than those taken as prescribed, and biological substances have emerged as a leading cause of preventable death in the United States. Th...

» Cross-talk between inflammation and coagulation in severe COVID-19: Association of leptin and classical pro-inflammatory markers with coagulation disorders in a single-center observational cohort study
30/04/26 20:00 from coronavirus
We performed a single-center observational cohort study on patients with COVID-19. We retrospectively analyzed 54 patients with confirmed SARS-CoV-2 infection, diagnosed as critically ill. Severely ill patients have a poor prognosis and ...

» Psychological resilience as a selective perceptual amplifier in post-crisis learning: a dual-pathway model of academic motivation, perceived school support, and cognitive engagement - a multi-country study based on PISA 2022
30/04/26 20:00 from covid-19
CONCLUSIONS: PR functions as a selective "perceptual amplifier" in post-crisis learning, primarily strengthening motivated students' ability to recognize PSS. The robust support→engagement pathway across national and gender groups unders...

» The influence of the COVID-19 public health emergency and dental coverage on the utilization of endodontic treatment in the United States
30/04/26 20:00 from coronavirus
CONCLUSION: The study highlights the critical role of benefit design in ensuring dental service utilization, particularly during public health emergencies. Oral health stakeholders must recognize the potential long-term consequences of d...

» Association between Internet addiction and mental health problems among Chinese adolescents in the post-COVID-19 pandemic era: a propensity score matching study
30/04/26 20:00 from covid-19
CONCLUSION: IA was associated with depression and anxiety among Chinese adolescents in the context of the post-COVID-19 pandemic era. Policymakers, parents, and school personnel should prioritize addressing IA to decrease mental health p...

» Reverse transcriptase mediated signal amplification in ligand binding assays
30/04/26 20:00 from sars-cov-2 spike protein
A simple method for enhanced detection of biological analytes is presented. It does not involve temperature cycling or temperatures above 37°C, can easily be integrated into existing protocols and requires only standard equipment. The pr...

» Public health emergency response through field epidemiology training and rapid response teams - a scoping review
30/04/26 20:00 from covid-19
CONCLUSION: While PHEW training including FETPs and RRTs are essential for building resilience against health threats, financial challenges, lack of standardized curricula and operating procedures hinders their effectiveness. Integrating...

» Third-trimester maternal COVID-19 infection and oxidative stress biomarkers in umbilical cord blood
30/04/26 20:00 from covid-19
CONCLUSIONS: Malondialdehyde and TAS were higher in the umbilical cord blood of COVID-19 positive mothers than in healthy controls during the third trimester. Third trimester maternal COVID-19 infection may be associated with increased o...

» Global Trends in Maternal Mortality and Efforts to Improve Maternal Outcomes Through Sociomedical Interventions
30/04/26 20:00 from covid-19
Maternal mortality continues to be a major global health concern that disproportionately affects low- and middle-income countries (LMICs), with the World Health Organisation (WHO) estimating a maternal death occurring every two minutes. ...

» Repurposing drug screen for the identification of helicase inhibitors from viruses of pandemic concern
30/04/26 20:00 from sars-cov-2
Several families of viruses encode helicase enzymes with essential roles in viral genome replication and transcription, including several RNA virus families of pandemic concern, such as coronaviruses and flaviviruses. Viral helicases are...

» Risk factors for mechanical ventilation and mortality among hospitalized Medicaid patients with COVID-19 in Kentucky, 2020-2021
30/04/26 20:00 from covid-19
This retrospective cohort study examined patient characteristics and comorbidities associated with mechanical ventilation and mortality among 28,128 hospitalized Kentucky Medicaid patients aged 18-64 years with COVID-19 in 2020-2021. Log...

» Reverse transcriptase mediated signal amplification in ligand binding assays
30/04/26 20:00 from sars-cov-2
A simple method for enhanced detection of biological analytes is presented. It does not involve temperature cycling or temperatures above 37°C, can easily be integrated into existing protocols and requires only standard equipment. The pr...

» A Novel Covalent Inhibitor Fragment for the SARS-CoV-2 Main Protease Identified by Target-Specific Deep Learning
30/04/26 20:00 from sars-cov-2
The SARS-CoV-2 main protease (M^(pro), also known as 3CL^(pro)) is an attractive antiviral drug target due to its essential role in viral replication and absence of human homologues. Development of new coronavirus-specific M^(pro) inhibi...

» Outcomes of descemet stripping automated endothelial keratoplasty using imported precut versus domestic surgeon-prepared corneas
30/04/26 20:00 from covid-19
CONCLUSION: Despite potentially greater initial ECD loss, imported precut corneas achieved comparable outcomes to domestic surgeon-prepared corneas, supporting their safety and efficacy.

» Reverse transcriptase mediated signal amplification in ligand binding assays
30/04/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
A simple method for enhanced detection of biological analytes is presented. It does not involve temperature cycling or temperatures above 37°C, can easily be integrated into existing protocols and requires only standard equipment. The pr...

» B cells gone broad: A deep dive into SARS-CoV-2 antibody breadth
30/04/26 20:00 from sars-cov-2
Antigen-specific B cell profiling uncovers key determinants of SARS-CoV-2 antibody breadth after infection and vaccination.

» Moving NMR infrastructures to remote access capabilities
30/04/26 20:00 from covid-19
Traditionally, Nuclear Magnetic Resonance (NMR) infrastructures have relied on in-person access, requiring researchers to travel to centralized facilities to conduct experiments. However, recent advancements in remote access technologies...

» Unmasking Adrenal Insufficiency in COVID-19: The Diagnostic Challenge of Concomitant Acute Kidney Injury and High Ileostomy Output
30/04/26 20:00 from sars-cov-2
BACKGROUND The coronavirus disease 2019 (COVID-19) pandemic has elucidated various extrapulmonary manifestations of severe acute respiratory syndrome coronavirus 2, including endocrine complications that affect the hypothalamic-pituitary...

» Repurposing drug screen for the identification of helicase inhibitors from viruses of pandemic concern
30/04/26 20:00 from covid-19
Several families of viruses encode helicase enzymes with essential roles in viral genome replication and transcription, including several RNA virus families of pandemic concern, such as coronaviruses and flaviviruses. Viral helicases are...

» Enhancing translation capacities of COVID-19 researchers through interdisciplinary collaboration: empathy, awareness, and action
30/04/26 20:00 from sars-cov-2
PURPOSE: Integrating societal considerations into public health research, particularly during crises, can foster public trust, support inclusive policy-making, and enhance technology development. Interdisciplinary collaboration may enhan...

» Boesenbergia rotunda-Derived Phytochemicals as Potent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): Insights From Molecular Docking and Dynamic Simulation
30/04/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
The papain-like protease (PLpro) of SARS-CoV-2 plays fundamental roles in its replication, and its mechanistic inhibition can impede the virus's replication and infection. Most Plpro inhibitors identified thus far are chemically synthesi...

» QT interval prolongation and its related factors before and after receiving lopinavir-ritonavir in the COVID-19 era: a historical cohort study
30/04/26 20:00 from covid-19
A historical cohort study in southern Iran investigated the effect of lopinavir-ritonavir treatment, with or without azithromycin and/or hydroxychloroquine, on QT interval prolongation in 500 confirmed COVID-19 patients. The outcomes sho...

» Reverse transcriptase mediated signal amplification in ligand binding assays
30/04/26 20:00 from covid-19
A simple method for enhanced detection of biological analytes is presented. It does not involve temperature cycling or temperatures above 37°C, can easily be integrated into existing protocols and requires only standard equipment. The pr...

» Dissecting urea-RNA interactions in SARS-CoV-2 virus: nucleobases as the primary denaturation hotspots
30/04/26 20:00 from sars-cov-2
RNA structure function relationships are of particular significance in the context of the SARS-CoV-2 genome, yet the molecular principles governing chemical denaturation of large, structured RNAs remain elusive. Here, we use all-atom mol...

» Safety and immunogenicity of a single-dose adenovirus-vectored rabies vaccine over 1 year in adults and children in Tanzania: interim data from an ongoing, partly randomised, controlled, phase 1b/2 trial
30/04/26 20:00 from covid-19
BACKGROUND: Rabies kills approximately 59 000 people each year. ChAdOx2 RabG, a simian adenovirus-vectored rabies vaccine candidate, has the potential to provide low-cost, single-dose pre-exposure rabies prophylaxis. We aimed to assess t...

» Stress fitness: A neuroscientific approach to building emotional resilience
30/04/26 20:00 from covid-19
Across the globe, rates of mood and anxiety disorders have been increasing steadily, a trend accelerated by the COVID-19 pandemic. Stress triggers these disorders, precipitating initial episodes and provoking relapses. In this perspectiv...

» Antiviral effect of lactoferrin against infectious bronchitis virus (IBV) are associated with alterations in the gastrointestinal microbiome
30/04/26 20:00 from covid-19
Coronaviruses (CoVs) are an enveloped, polymorphic, positive-sense single-stranded RNA viruses. Currently, both humans and animals are threatened by CoVs, making them a major public health concern. Among the four genera of the family Cor...

» Phospholipase PLA2G5-triggered hemolysis emerges as a contributor to sepsis lethality
30/04/26 20:00 from sars-cov-2
Despite extensive advances in understanding sepsis pathophysiology, treatment outcomes have not substantially improved. In this issue, Takahama and colleagues identified phospholipase A2 Group V (PLA2G5) as a contributor to sepsis lethal...

» Trends in accidental poisoning and exposure to noxious substances involving drugs, medicaments, and biological substances-related deaths: A nationwide US analysis, 1999 to 2023
30/04/26 20:00 from sars-cov-2
Unintentional poisoning and exposure to harmful substances involving illicit drugs, medications other than those taken as prescribed, and biological substances have emerged as a leading cause of preventable death in the United States. Th...

» The influence of the COVID-19 public health emergency and dental coverage on the utilization of endodontic treatment in the United States
30/04/26 20:00 from sars-cov-2
CONCLUSION: The study highlights the critical role of benefit design in ensuring dental service utilization, particularly during public health emergencies. Oral health stakeholders must recognize the potential long-term consequences of d...

» Trends in accidental poisoning and exposure to noxious substances involving drugs, medicaments, and biological substances-related deaths: A nationwide US analysis, 1999 to 2023
30/04/26 20:00 from coronavirus
Unintentional poisoning and exposure to harmful substances involving illicit drugs, medications other than those taken as prescribed, and biological substances have emerged as a leading cause of preventable death in the United States. Th...

» Cross-talk between inflammation and coagulation in severe COVID-19: Association of leptin and classical pro-inflammatory markers with coagulation disorders in a single-center observational cohort study
30/04/26 20:00 from coronavirus
We performed a single-center observational cohort study on patients with COVID-19. We retrospectively analyzed 54 patients with confirmed SARS-CoV-2 infection, diagnosed as critically ill. Severely ill patients have a poor prognosis and ...

» Boesenbergia rotunda-Derived Phytochemicals as Potent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): Insights From Molecular Docking and Dynamic Simulation
30/04/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
The papain-like protease (PLpro) of SARS-CoV-2 plays fundamental roles in its replication, and its mechanistic inhibition can impede the virus's replication and infection. Most Plpro inhibitors identified thus far are chemically synthesi...

» Trends in accidental poisoning and exposure to noxious substances involving drugs, medicaments, and biological substances-related deaths: A nationwide US analysis, 1999 to 2023
30/04/26 20:00 from coronavirus
Unintentional poisoning and exposure to harmful substances involving illicit drugs, medications other than those taken as prescribed, and biological substances have emerged as a leading cause of preventable death in the United States. Th...

» Cross-talk between inflammation and coagulation in severe COVID-19: Association of leptin and classical pro-inflammatory markers with coagulation disorders in a single-center observational cohort study
30/04/26 20:00 from coronavirus
We performed a single-center observational cohort study on patients with COVID-19. We retrospectively analyzed 54 patients with confirmed SARS-CoV-2 infection, diagnosed as critically ill. Severely ill patients have a poor prognosis and ...

» Boesenbergia rotunda-Derived Phytochemicals as Potent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): Insights From Molecular Docking and Dynamic Simulation
30/04/26 20:00 from SARS-CoV-2 and Sars-Cov comparisons
The papain-like protease (PLpro) of SARS-CoV-2 plays fundamental roles in its replication, and its mechanistic inhibition can impede the virus's replication and infection. Most Plpro inhibitors identified thus far are chemically synthesi...