» Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae in paediatric patients in Japan (2020-2023)
11/12/25 19:00 from coronavirus
Introduction. Streptococcus pneumoniae remains a major pathogen causing invasive diseases in children worldwide. Although pneumococcal conjugate vaccines (PCVs) have significantly reduced the disease burden, non-vaccine serotypes and ant...
» Expanding the causes of Fever of Unknown Origin in immunocompromised patients: report of two cases highlighting the role of SARS-CoV-2
11/12/25 19:00 from sars-cov-2
Fever of Unknown Origin (FUO) remains a diagnostic challenge for clinicians, with multiple infectious and non-infectious etiologies. SARS-CoV-2 can determine a prolonged viral shedding in the immunocompromised host, firstly in those rece...
» Development of a Recombinant Single-Cycle Influenza Viral Vector as an Intranasal Vaccine against SARS-CoV-2 and SARS-like Betacoronaviruses
11/12/25 19:00 from coronavirus
The COVID-19 pandemic has demonstrated the detrimental potential of zoonotic coronavirus transmission to human populations. Effective vaccines capable of eliciting immunity to SARS-CoV-2 have been pivotal in mitigating the spread of the ...
» Administration of antivirals, IL-6 inhibitors, monoclonal neutralizing antibodies and systemic corticosteroids in acute SARS-CoV-2 infection do not reduce the subsequent burden of Long-COVID symptoms
11/12/25 19:00 from sars-cov-2
CONCLUSIONS: Some drug classes showed a protective effect that was however not confirmed in multivariable analyses, underlining the importance of adjusting for a comprehensive number of covariates. Clinicians should consider the possibil...
» MIS-C pathogenesis: immune dysregulation & viral triggers
11/12/25 19:00 from coronavirus
Multisystem Inflammatory Syndrome in Children (MIS-C) is a serious condition emerging during the COVID-19 pandemic, strongly associated with prior SARS-CoV-2 infection. Characterized by systemic inflammation affecting multiple organs, MI...
» The importance of epistasis in the evolution of viral pathogens
11/12/25 19:00 from sars-cov-2
Understanding the genetic and genomic underpinnings of infectious disease outbreaks has emerged as a frontier of epidemiology. Here, we argue that epistasis-where the phenotypic effects of mutations or gene variants are dictated by the p...
» DE02 Read the virtual room: the value of in-person undergraduate teaching
11/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
The COVID-19 pandemic necessitated a transition from face-to-face to virtual undergraduate teaching. Medical school curricula now typically provide a blend of both, offering convenience and flexibility to students and educators alike. Ho...
» AI-driven prediction of severe respiratory sequelae in COVID-19 patients
11/12/25 19:00 from coronavirus
CONCLUSIONS: Our AI-driven predictive model demonstrates strong potential for the early identification of respiratory sequelae in COVID-19 patients. By applying the K-means algorithm to cluster patients based on clinical characteristics,...
» Development of a Recombinant Single-Cycle Influenza Viral Vector as an Intranasal Vaccine against SARS-CoV-2 and SARS-like Betacoronaviruses
11/12/25 19:00 from sars-cov-2
The COVID-19 pandemic has demonstrated the detrimental potential of zoonotic coronavirus transmission to human populations. Effective vaccines capable of eliciting immunity to SARS-CoV-2 have been pivotal in mitigating the spread of the ...
» Brain histopathological changes caused by SARS-CoV-2 infection
11/12/25 19:00 from coronavirus
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affected over 775 million people in 232 countries and regions between 2020 and 2024, causing over seven million deaths and b...
» MIS-C pathogenesis: immune dysregulation & viral triggers
11/12/25 19:00 from sars-cov-2
Multisystem Inflammatory Syndrome in Children (MIS-C) is a serious condition emerging during the COVID-19 pandemic, strongly associated with prior SARS-CoV-2 infection. Characterized by systemic inflammation affecting multiple organs, MI...
» P147 Exploring the impact of age and deprivation on malignant melanoma diagnoses during the COVID-19 pandemic in England: a national retrospective cohort study
11/12/25 19:00 from coronavirus
Diagnoses of cancers in all body sites were reduced in England during the COVID-19 pandemic. Older populations were advised to stay at home due to greater risk of mortality from COVID-19, and more deprived populations had more difficulty...
» DE02 Read the virtual room: the value of in-person undergraduate teaching
11/12/25 19:00 from coronavirus
The COVID-19 pandemic necessitated a transition from face-to-face to virtual undergraduate teaching. Medical school curricula now typically provide a blend of both, offering convenience and flexibility to students and educators alike. Ho...
» Expanding the causes of Fever of Unknown Origin in immunocompromised patients: report of two cases highlighting the role of SARS-CoV-2
11/12/25 19:00 from Sars-Cov-2 origins
Fever of Unknown Origin (FUO) remains a diagnostic challenge for clinicians, with multiple infectious and non-infectious etiologies. SARS-CoV-2 can determine a prolonged viral shedding in the immunocompromised host, firstly in those rece...
» P062 National clinical reaudit on managing adults with bullous pemphigoid 2024: shifting clinical practices
11/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
Bullous pemphigoid (BP) is the most prevalent auto-immune blistering disorder in Western populations. It disproportionately affects older adults and is associated with significant morbidity. Following the British Association of Dermatolo...
» DS22 'We need to talk': the effect of departmental discussion of British Society for Dermatological Surgery sustainability guidance on use of absorbable suture material and its environmental impact
11/12/25 19:00 from coronavirus
The 2022 British Society for Dermatological Surgery (BSDS) sustainability guidelines recommend considering use of absorbable sutures for surgical wound closure. This is to reduce footfall from reattendance for suture removal, to free the...
» Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae in paediatric patients in Japan (2020-2023)
11/12/25 19:00 from covid-19
Introduction. Streptococcus pneumoniae remains a major pathogen causing invasive diseases in children worldwide. Although pneumococcal conjugate vaccines (PCVs) have significantly reduced the disease burden, non-vaccine serotypes and ant...
» BG02 (P062) National clinical reaudit on managing adults with bullous pemphigoid 2024: shifting clinical practices
11/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
Bullous pemphigoid (BP) is the most prevalent auto-immune blistering disorder in Western populations. It disproportionately affects older adults and is associated with significant morbidity. Following the British Association of Dermatolo...
» P062 National clinical reaudit on managing adults with bullous pemphigoid 2024: shifting clinical practices
11/12/25 19:00 from coronavirus
Bullous pemphigoid (BP) is the most prevalent auto-immune blistering disorder in Western populations. It disproportionately affects older adults and is associated with significant morbidity. Following the British Association of Dermatolo...
» BG02 (P062) National clinical reaudit on managing adults with bullous pemphigoid 2024: shifting clinical practices
11/12/25 19:00 from coronavirus
Bullous pemphigoid (BP) is the most prevalent auto-immune blistering disorder in Western populations. It disproportionately affects older adults and is associated with significant morbidity. Following the British Association of Dermatolo...
» BT13 A remote nurse prescriber service: enhancing capacity for new patients and streamlining services to ensure high-quality patient care and satisfaction
11/12/25 19:00 from coronavirus
Streamlining outpatient services and enhancing patient care has been a priority for the National Health Service (NHS) and private providers. 'Getting It Right First Time' states that stable patients can be reviewed remotely via phone or ...
» CPC15 Vulval squamous cell carcinoma is an under-reported cancer associated with poor outcomes: a national cohort study of the incidence and survival in England
11/12/25 19:00 from coronavirus
Epidemiological data are limited for vulval squamous cell carcinoma (VSCC). This retrospective, national cohort study reports the incidence and survival of VSCC from 2013 to 2020 in England. Data were extracted from the National Disease ...
» Expanding the causes of Fever of Unknown Origin in immunocompromised patients: report of two cases highlighting the role of SARS-CoV-2
11/12/25 19:00 from Covid-19 origins
Fever of Unknown Origin (FUO) remains a diagnostic challenge for clinicians, with multiple infectious and non-infectious etiologies. SARS-CoV-2 can determine a prolonged viral shedding in the immunocompromised host, firstly in those rece...
» P074 Pemphigus vulgaris management after COVID-19: challenges of low- and middle-income countries
11/12/25 19:00 from coronavirus
Pemphigus vulgaris is a rare autoimmune skin blistering disorder. Corticosteroids have remained the cornerstone of management plans for decades. Recently rituximab has established its central place as steroid-sparing agent and has revolu...
» Geographical and Temporal Trends in Industry Engagement Among Otolaryngologists 2017 to 2023
11/12/25 19:00 from covid-19
CONCLUSIONS: The number of IPs decreased significantly during the COVID-19 pandemic but has approached pre-pandemic levels, driven by increased high-value payments. A small number of companies account for most payments. There is signific...
» P107 Association between the COVID-19 vaccination programme and incidence rates of bullous pemphigoid, herpes zoster and urticaria in the UK: an interrupted time series analysis
11/12/25 19:00 from coronavirus
Following the introduction of the COVID-19 vaccination programme, there were numerous reports of adverse cutaneous reactions. In particular, several population-based studies reported associations between the COVID-19 vaccines and bullous...
» PA45 Successful implementation of referral triage in a paediatric dermatology service
11/12/25 19:00 from coronavirus
The demand for paediatric dermatology services has risen significantly in recent years across the UK, particularly following the COVID-19 pandemic. This has led to a sharp increase in waiting times, putting secondary care dermatology ser...
» Should We Screen Sooner? Elevated CRC Incidence in Solid Organ Transplant Recipients in the United States Before and After the COVID-19 Pandemic
11/12/25 19:00 from covid-19
CONCLUSION: SOT recipients in the United States exhibit a significantly higher long-term CRC risk, a disparity that appears to have widened after the pandemic. These findings underscore the need to revisit CRC screening strategies in SOT...
» P138 A national retrospective cohort study reporting the epidemiology of vascular soft-tissue sarcomas in England 2013-2020
11/12/25 19:00 from Covid-19 origins
Vascular soft-tissue sarcomas (VSTSs), while rare, are a diverse group of sarcomas that carry a poor prognosis and have limited management options. The most common subtype is angiosarcoma, but this group also includes lymphangiosarcomas,...
» BH08 Unprovoked pulmonary emboli in a patient with alopecia areata treated with ritlecitinib: a case report
11/12/25 19:00 from Covid-19 origins
Alopecia areata (AA) is a chronic autoimmune condition characterized by nonscarring hair loss due to an aberrant immune response targeting hair follicles. The results of large clinical trials have demonstrated Janus kinase inhibitors to ...
» Inpatient Management of Bronchiolitis Before and After the COVID-19 Pandemic
11/12/25 19:00 from covid-19
Introduction Bronchiolitis is the most common cause of respiratory-related hospital admissions in children under two years. It is typically caused by viral infections, most commonly respiratory syncytial virus (RSV). Despite the availabi...
» Expanding the causes of Fever of Unknown Origin in immunocompromised patients: report of two cases highlighting the role of SARS-CoV-2
11/12/25 19:00 from covid-19
Fever of Unknown Origin (FUO) remains a diagnostic challenge for clinicians, with multiple infectious and non-infectious etiologies. SARS-CoV-2 can determine a prolonged viral shedding in the immunocompromised host, firstly in those rece...
» From Black Death to COVID-19: Lessons Learned from the Past Pandemics
11/12/25 19:00 from covid-19
INTRODUCTION: Throughout human history, pandemics such as Black Death, Smallpox, Spanish Flu and COVID-19 caused global outbreaks and spread of infectious pathogens resulting in significant morbidity and mortality. They also had profound...
» Administration of antivirals, IL-6 inhibitors, monoclonal neutralizing antibodies and systemic corticosteroids in acute SARS-CoV-2 infection do not reduce the subsequent burden of Long-COVID symptoms
11/12/25 19:00 from covid-19
CONCLUSIONS: Some drug classes showed a protective effect that was however not confirmed in multivariable analyses, underlining the importance of adjusting for a comprehensive number of covariates. Clinicians should consider the possibil...
» Case Report: CytoSorb hemoadsorption as an adjunctive therapy in critically ill pregnant women with COVID-19 and acute kidney injury-a case series
11/12/25 19:00 from covid-19
CONCLUSION: In this small case series, adjunctive CytoSorb hemoadsorption was associated with rapid clinical stabilization and recovery in critically ill pregnant women with COVID-19, AKI, and hyperinflammation. These promising results w...
» Identification of a novel dual-targeting peptide inhibitor of SARS-CoV-2 RBD and NRP1 through structure-based virtual screening
11/12/25 19:00 from sars-cov-2
CONCLUSION: In conclusion, peptide-1 is a highly effective and low-toxicity antiviral inhibitor that dual-targets RBD and NRP1.
» AI-driven prediction of severe respiratory sequelae in COVID-19 patients
11/12/25 19:00 from sars-cov-2
CONCLUSIONS: Our AI-driven predictive model demonstrates strong potential for the early identification of respiratory sequelae in COVID-19 patients. By applying the K-means algorithm to cluster patients based on clinical characteristics,...
» The Adaptive Role of Entorhinal Cortical Thickness in Post-COVID 19 Cognitive Impairment
11/12/25 19:00 from covid-19
CONCLUSION: Our findings of increased entorhinal cortical thickness, together with impaired cognitive scores, may indicate a flexible role of EC thickness in compensatory mechanisms of cognition.
» A Modular Encapsulation System for Precision Delivery of Proteins, Nucleic Acids, and Small Molecules
11/12/25 19:00 from sars-cov-2
Targeted nanoparticles have the potential to revolutionize therapeutics for medical applications. Here, we demonstrate the utility of a flexible precision nanovesicle delivery system for functional delivery of DNA, RNA, proteins, and dru...
» Gender Inequality and Crude Suicide Rates in Türkiye: A Nationwide Retrospective Ecological Study
11/12/25 19:00 from covid-19
CONCLUSION: Gender inequality indicators were related to suicide. That relationship may vary across different age and gender groups. The findings may be limited to low- and middle-income countries. Suicide prevention interventions should...
» Combined Use of Engineered PfAGO and LbCas12a for Nucleic Acid Detection
11/12/25 19:00 from sars-cov-2
The COVID-19 pandemic has underscored the urgent need for rapid, accurate, and accessible nucleic acid detection technologies. Here, we present NAEPLS (Nucleic Acid Detection Based on Engineered PfAgo and LbCas12a with Split crRNA), a no...
» Revisiting Conservative Approaches to Fracture Care Such As Close Contact Casting in the Elderly Co-morbid Patient: A Technical Report
11/12/25 19:00 from covid-19
Close contact casting (CCC) is a non-surgical treatment for certain types of fractures, using tight moulding to achieve anatomical alignment. During the COVID-19 pandemic, when healthcare systems globally were under severe strain, conser...
» Brain histopathological changes caused by SARS-CoV-2 infection
11/12/25 19:00 from sars-cov-2
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affected over 775 million people in 232 countries and regions between 2020 and 2024, causing over seven million deaths and b...
» Impact of COVID-19 Pandemic on Testing for Hepatitis B in British Columbia, Canada: An Interrupted Time Series Analysis
11/12/25 19:00 from covid-19
CONCLUSIONS: The pandemic and related policies were associated with decreases in HBsAg and HBV DNA testing in 2020, and testing remained lower than predicted throughout 2021 and 2022. Additional efforts to increase HBV testing are needed...
» P147 Exploring the impact of age and deprivation on malignant melanoma diagnoses during the COVID-19 pandemic in England: a national retrospective cohort study
11/12/25 19:00 from sars-cov-2
Diagnoses of cancers in all body sites were reduced in England during the COVID-19 pandemic. Older populations were advised to stay at home due to greater risk of mortality from COVID-19, and more deprived populations had more difficulty...
» DE02 Read the virtual room: the value of in-person undergraduate teaching
11/12/25 19:00 from sars-cov-2
The COVID-19 pandemic necessitated a transition from face-to-face to virtual undergraduate teaching. Medical school curricula now typically provide a blend of both, offering convenience and flexibility to students and educators alike. Ho...
» Exploring Stress, Fatigue, Burnout, and Resilience Among Healthcare Personnel in Southern and South-Eastern Asia: A Scoping Review
11/12/25 19:00 from covid-19
CONCLUSION: There are many studies assessing burnout, stress, and resilience among HCP in Southern and South-eastern Asia, yet gaps remain in identifying effective resilience-building interventions. Further research is needed to assess t...
» The importance of epistasis in the evolution of viral pathogens
11/12/25 19:00 from covid-19
Understanding the genetic and genomic underpinnings of infectious disease outbreaks has emerged as a frontier of epidemiology. Here, we argue that epistasis-where the phenotypic effects of mutations or gene variants are dictated by the p...
» DS22 'We need to talk': the effect of departmental discussion of British Society for Dermatological Surgery sustainability guidance on use of absorbable suture material and its environmental impact
11/12/25 19:00 from sars-cov-2
The 2022 British Society for Dermatological Surgery (BSDS) sustainability guidelines recommend considering use of absorbable sutures for surgical wound closure. This is to reduce footfall from reattendance for suture removal, to free the...
» Development of a Recombinant Single-Cycle Influenza Viral Vector as an Intranasal Vaccine against SARS-CoV-2 and SARS-like Betacoronaviruses
11/12/25 19:00 from covid-19
The COVID-19 pandemic has demonstrated the detrimental potential of zoonotic coronavirus transmission to human populations. Effective vaccines capable of eliciting immunity to SARS-CoV-2 have been pivotal in mitigating the spread of the ...
» P062 National clinical reaudit on managing adults with bullous pemphigoid 2024: shifting clinical practices
11/12/25 19:00 from sars-cov-2
Bullous pemphigoid (BP) is the most prevalent auto-immune blistering disorder in Western populations. It disproportionately affects older adults and is associated with significant morbidity. Following the British Association of Dermatolo...
» BG02 (P062) National clinical reaudit on managing adults with bullous pemphigoid 2024: shifting clinical practices
11/12/25 19:00 from sars-cov-2
Bullous pemphigoid (BP) is the most prevalent auto-immune blistering disorder in Western populations. It disproportionately affects older adults and is associated with significant morbidity. Following the British Association of Dermatolo...
» Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025
10/12/25 19:00 from Coronavirus origins
During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 p...
» Analyzing global research trends in hepatology during Coronavirus Disease 2019: a bibliometric analysis
10/12/25 19:00 from Coronavirus origins
CONCLUSION: Top articles in our analysis focused on liver transplantation, pathophysiology, and healthcare management. It can aid researchers in assessing the effectiveness of different treatment modalities for hepatic impairment in COVI...
» Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025
10/12/25 19:00 from Sars-Cov-2 origins
During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 p...
» Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025
10/12/25 19:00 from Covid-19 origins
During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 p...
» Analyzing global research trends in hepatology during Coronavirus Disease 2019: a bibliometric analysis
10/12/25 19:00 from Sars-Cov-2 origins
CONCLUSION: Top articles in our analysis focused on liver transplantation, pathophysiology, and healthcare management. It can aid researchers in assessing the effectiveness of different treatment modalities for hepatic impairment in COVI...
» Analyzing global research trends in hepatology during Coronavirus Disease 2019: a bibliometric analysis
10/12/25 19:00 from Covid-19 origins
CONCLUSION: Top articles in our analysis focused on liver transplantation, pathophysiology, and healthcare management. It can aid researchers in assessing the effectiveness of different treatment modalities for hepatic impairment in COVI...
» AI tools aim to speed up outbreak modeling
10/12/25 19:00 from covid-19 and viral hemorrhagic fevers
DARPA program could help researchers build transparent, editable models of viral spread in days instead of weeks.
» Post-exposure prevention in Marburg virus outbreaks: potential role of remdesivir in emergency response
10/12/25 19:00 from covid-19 and viral hemorrhagic fevers
Marburg virus (MARV), a close relative of the Ebola virus, causes severe hemorrhagic fevers with a case fatality rate of up to 88%. In the absence of specific treatment or vaccine, its rapid spread through epidemics in Africa, particular...
» Effectiveness of 2023-2024 Coronavirus Disease 2019 (COVID-19) Vaccines in Pregnant Women
10/12/25 19:00 from covid-19
Pregnant women are at higher risk of severe coronavirus disease 2019 (COVID-19) compared with nonpregnant women of reproductive age. During 2023-2024, the Centers for Disease Control and Prevention recommended COVID-19 vaccination for ev...
» Hyrox©: A Descriptive Analysis of Participation Trends Among Over 275,000 Athletes in the New Fitness Modality
10/12/25 19:00 from covid-19
High-intensity functional training (HIFT) is a competition and training modality that has gained popularity over the last few years. As a result, disciplines like Hyrox© have emerged recently, responding to the need for a fixed competiti...
» Trends in Proportion of Delirium Among Older Emergency Department Patients in South Korea, 2017-2022
10/12/25 19:00 from covid-19
CONCLUSION: Delirium-related ED visits among older adults showed a notable 7.8% decrease during the late pandemic period, with key risk groups identified, particularly adults 65-74 of age (40.6% increase) and those referred from institut...
» Limiting Albuterol Use by EMS at the Start of the COVID-19 Pandemic: A Retrospective Analysis of Rapid Deimplementation
10/12/25 19:00 from covid-19
CONCLUSION: Deimplementation of albuterol administration in the beginning of the COVID-19 pandemic was significant in its rate and success in adherence to guidelines when compared to other changes in EMS policies, procedures, and protoco...
» Intersectional Analysis of Suicide-related Emergency Department Visits in Youth in California, 2018-2021
10/12/25 19:00 from covid-19
CONCLUSION: Suicide-related ED visits increased for all youth during COVID-19, with the sharpest rise among AAPI and AI/AN females. Asian American and Pacific Islander females 8-12 and 13-17 years of age showed especially large increases...
» Pandemic security needs national leadership
10/12/25 19:00 from covid-19
In a world facing escalating risks from conflict, climate change, and emerging infectious diseases, health systems are the first line of defense for protecting people, economies, and stability. Although pandemic preparedness is often fra...
» AI tools aim to speed up outbreak modeling
10/12/25 19:00 from covid-19
DARPA program could help researchers build transparent, editable models of viral spread in days instead of weeks.
» Comparative evaluation of five rapid PCR platforms for respiratory virus detection
10/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSION: Among four platforms, the M10 (30-min version) and Flash10 platforms demonstrated the highest agreement rates with the GeneXpert. The variability in performance highlights the importance of independent platform evaluation.
» Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025
10/12/25 19:00 from covid-19
During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 p...
» Detection of Paraburkholderia in Clinical Specimens Associated with Use of Nonsterile Ultrasound Gel for Percutaneous Procedures - United States, Canada, and Israel, May 2023⎯April 2025
10/12/25 19:00 from covid-19
Contaminated nonsterile ultrasound gels have been implicated in outbreaks of Burkholderia infections associated with improper infection control practices before or during percutaneous procedures. In August 2024, the Minnesota Department ...
» Effectiveness of 2023-2024 Coronavirus Disease 2019 (COVID-19) Vaccines in Pregnant Women
10/12/25 19:00 from coronavirus
Pregnant women are at higher risk of severe coronavirus disease 2019 (COVID-19) compared with nonpregnant women of reproductive age. During 2023-2024, the Centers for Disease Control and Prevention recommended COVID-19 vaccination for ev...
» Comparative evaluation of five rapid PCR platforms for respiratory virus detection
10/12/25 19:00 from covid-19
CONCLUSION: Among four platforms, the M10 (30-min version) and Flash10 platforms demonstrated the highest agreement rates with the GeneXpert. The variability in performance highlights the importance of independent platform evaluation.
» Trends in Proportion of Delirium Among Older Emergency Department Patients in South Korea, 2017-2022
10/12/25 19:00 from coronavirus
CONCLUSION: Delirium-related ED visits among older adults showed a notable 7.8% decrease during the late pandemic period, with key risk groups identified, particularly adults 65-74 of age (40.6% increase) and those referred from institut...
» COVID-19 vaccination data management and visualization systems for improved decision-making: Lessons learnt from Africa CDC Saving Lives and Livelihoods program
10/12/25 19:00 from covid-19
The DHIS2 system enabled real-time tracking of vaccine distribution and administration to facilitate data-driven decisions. Experts from the Africa Centres for Disease Control and Prevention (Africa CDC) Monitoring and Evaluation (M&E) a...
» Limiting Albuterol Use by EMS at the Start of the COVID-19 Pandemic: A Retrospective Analysis of Rapid Deimplementation
10/12/25 19:00 from coronavirus
CONCLUSION: Deimplementation of albuterol administration in the beginning of the COVID-19 pandemic was significant in its rate and success in adherence to guidelines when compared to other changes in EMS policies, procedures, and protoco...
» Conspiratorial beliefs and reduced vaccine acceptance: Understanding the role of perspective-taking
10/12/25 19:00 from covid-19
Surges in infectious diseases often bring illness and conspiratorial beliefs. Such beliefs can hinder the adoption of public health advice, including vaccination. Because conspiratorial beliefs are difficult to reduce once entrenched, it...
» Trends in Proportion of Delirium Among Older Emergency Department Patients in South Korea, 2017-2022
10/12/25 19:00 from sars-cov-2
CONCLUSION: Delirium-related ED visits among older adults showed a notable 7.8% decrease during the late pandemic period, with key risk groups identified, particularly adults 65-74 of age (40.6% increase) and those referred from institut...
» Open science: My insights into data sharing, preregistration, and replication
10/12/25 19:00 from covid-19
After a decade of implementing open science practices as a principal investigator, mentor, data repository founder, and editor-in-chief, I have learned that the question is not whether researchers should adopt these practices but how to ...
» Intersectional Analysis of Suicide-related Emergency Department Visits in Youth in California, 2018-2021
10/12/25 19:00 from coronavirus
CONCLUSION: Suicide-related ED visits increased for all youth during COVID-19, with the sharpest rise among AAPI and AI/AN females. Asian American and Pacific Islander females 8-12 and 13-17 years of age showed especially large increases...
» Limiting Albuterol Use by EMS at the Start of the COVID-19 Pandemic: A Retrospective Analysis of Rapid Deimplementation
10/12/25 19:00 from sars-cov-2
CONCLUSION: Deimplementation of albuterol administration in the beginning of the COVID-19 pandemic was significant in its rate and success in adherence to guidelines when compared to other changes in EMS policies, procedures, and protoco...
» COVID-19-induced educational disruptions and children's executive functioning: A longitudinal cohort study
10/12/25 19:00 from covid-19
Literature suggests that the COVID-19 pandemic may have disrupted children's executive functioning (EF) development, but most studies rely on caregiver reports, cross-sectional data, or comparisons across cohorts. We build on the existin...
» Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025
10/12/25 19:00 from coronavirus
During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 p...
» Intersectional Analysis of Suicide-related Emergency Department Visits in Youth in California, 2018-2021
10/12/25 19:00 from sars-cov-2
CONCLUSION: Suicide-related ED visits increased for all youth during COVID-19, with the sharpest rise among AAPI and AI/AN females. Asian American and Pacific Islander females 8-12 and 13-17 years of age showed especially large increases...
» Community-Driven, Text Message-Based COVID-19 Surveillance System, Los Angeles County, California, USA, 2020-2024
10/12/25 19:00 from covid-19
Respiratory virus indicators were unreliable at the onset of the COVID-19 pandemic when testing availability was limited and residents with mild symptoms were advised to avoid unnecessary medical care. The Los Angeles County Department o...
» Comparative evaluation of five rapid PCR platforms for respiratory virus detection
10/12/25 19:00 from coronavirus
CONCLUSION: Among four platforms, the M10 (30-min version) and Flash10 platforms demonstrated the highest agreement rates with the GeneXpert. The variability in performance highlights the importance of independent platform evaluation.
» Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025
10/12/25 19:00 from sars-cov-2
During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 p...
» Community-Driven, Text Message-Based COVID-19 Surveillance System, Los Angeles County, California, USA, 2020-2024
10/12/25 19:00 from coronavirus
Respiratory virus indicators were unreliable at the onset of the COVID-19 pandemic when testing availability was limited and residents with mild symptoms were advised to avoid unnecessary medical care. The Los Angeles County Department o...
» Comparative evaluation of five rapid PCR platforms for respiratory virus detection
10/12/25 19:00 from sars-cov-2
CONCLUSION: Among four platforms, the M10 (30-min version) and Flash10 platforms demonstrated the highest agreement rates with the GeneXpert. The variability in performance highlights the importance of independent platform evaluation.
» COVID-19 vaccine hesitancy among Latinx individuals in North Texas: Understandings from a community study
10/12/25 19:00 from coronavirus
Despite the advent of effective COVID-19 vaccines, COVID-19 vaccine hesitancy persists in the United States. Some minoritized populations, including Latinx individuals, experience elevated risk for COVID-19 due to numerous social and eco...
» Community-Driven, Text Message-Based COVID-19 Surveillance System, Los Angeles County, California, USA, 2020-2024
10/12/25 19:00 from sars-cov-2
Respiratory virus indicators were unreliable at the onset of the COVID-19 pandemic when testing availability was limited and residents with mild symptoms were advised to avoid unnecessary medical care. The Los Angeles County Department o...
» Advances in bedside imaging: lung ultrasound
10/12/25 19:00 from coronavirus
Lung ultrasound has become an indispensable tool in the management of acute respiratory failure, offering real-time, radiation-free bedside imaging. Its portability, repeatability, and high sensitivity for detecting pulmonary abnormaliti...
» COVID-19 vaccine hesitancy among Latinx individuals in North Texas: Understandings from a community study
10/12/25 19:00 from sars-cov-2
Despite the advent of effective COVID-19 vaccines, COVID-19 vaccine hesitancy persists in the United States. Some minoritized populations, including Latinx individuals, experience elevated risk for COVID-19 due to numerous social and eco...
» Pityriasis rubra pilaris triggered by vaccination
10/12/25 19:00 from sars-cov-2
CONCLUSIONS: In conclusion, PRP post-vaccination is rare and likely underdiagnosed, but recognizing the association is important to evaluate any new exposures to the trigger. A thorough patient history, including recent vaccinations, is ...
» Invention, innovation, and commercialisation in British biophysics
10/12/25 19:00 from sars-cov-2 spike protein
British biophysics has a tradition of scientific invention and innovation, resulting in new technologies transforming biological insight, such as rapid DNA sequencing, super-resolution and label-free microscopy, high-throughput and singl...
» Impact of emerging and re-emerging viral infections on periodontitis progression
10/12/25 19:00 from coronavirus
Periodontitis is a chronic inflammatory disease that progressively destroys the tooth-supporting structures, including the gums, periodontal ligament, and alveolar bone. This destruction is primarily driven not by the bacteria themselves...
» The night has many faces: When schistocytes step out of line
10/12/25 19:00 from sars-cov-2
We present a case study of a patient with paroxysmal nocturnal haemoglobinuria (PNH) which first presented clinically as a haemolytic crisis, potentially triggered by a SARS-CoV-2 infection. This case highlights the diagnostic challenges...
» GP Consultations for Herpes Zoster After COVID-19 Vaccination: A Self-Controlled Cohort Study Based on Electronic Health Record Data from the Netherlands
10/12/25 19:00 from coronavirus
CONCLUSIONS: Our study showed a slight increased risk of herpes zoster when taking into account all doses and all types of vaccines. After stratification on vaccine type, no increased risk of herpes zoster after the primary vaccination s...
» A comprehensive longitudinal analysis of the cellular immune response specific to the spike protein in healthcare workers vaccinated against SARS-CoV-2- ORCHESTRA Project
10/12/25 19:00 from sars-cov-2 spike protein
INTRODUCTION: The long-term dynamics of T-cell immunity following SARS-CoV-2 vaccination, essential for durable protection, remain incompletely understood. This study, therefore, aimed to investigate the kinetics and persistence of spike...
» Impact of emerging and re-emerging viral infections on periodontitis progression
10/12/25 19:00 from sars-cov-2
Periodontitis is a chronic inflammatory disease that progressively destroys the tooth-supporting structures, including the gums, periodontal ligament, and alveolar bone. This destruction is primarily driven not by the bacteria themselves...
» Garlic-Derived Phytochemical Candidates Predicted to Disrupt SARS-CoV-2 RBD-ACE2 Binding and Inhibit Viral Entry
10/12/25 19:00 from sars-cov-2 spike protein
The emergence of SARS-CoV-2 and its rapid global spread underscores the urgent need for novel therapeutic strategies. This study investigates the antiviral potential of Allium sativum (garlic) extracts against SARS-CoV-2, focusing on dis...
» Pain in Long COVID: A scoping review of clinical characteristics and patterns of manifestation
10/12/25 19:00 from sars-cov-2
to map the available scientific evidence on the clinical characteristics and patterns of pain manifestation (location, frequency, duration, intensity, and quality) in individuals with Long COVID.
» In Silico Analysis of C60 Fullerene Interaction with TMPRSS2: Toward Novel COVID-19 Prevention Approaches
10/12/25 19:00 from sars-cov-2 spike protein
The recent global spread of the SARS-CoV-2 pathogen, which causes COVID-19, and its rapid mutation, requires the fast development of effective preventive and treatment measures. According to WHO reports, over 778 million confirmed cases ...
» Pain in Long COVID: A scoping review of clinical characteristics and patterns of manifestation
10/12/25 19:00 from coronavirus
to map the available scientific evidence on the clinical characteristics and patterns of pain manifestation (location, frequency, duration, intensity, and quality) in individuals with Long COVID.
» THE ROLE OF DIGESTIVE MANIFESTATIONS IN COVID-19 MORTALITY: EVIDENCES FROM BRAZIL'S FIRST EPIDEMIC WAVE
10/12/25 19:00 from sars-cov-2
CONCLUSION: Hepatic abnormalities and gastrointestinal symptoms are important markers of COVID-19 severity. Diarrhea, liver enzyme alterations, and serum albumin levels were significant predictors of mortality. Future strategies should p...
» Specific Instability of HLA-A*03:01 Expression in HEK-293 Cells
10/12/25 19:00 from sars-cov-2 spike protein
HEK-293 is a highly transfectable human cell line widely used as a model for protein expression. Since large amounts of cells are often required for the purification of HLA immunopeptidomes, suspension-growing variants, such as HEK-293F,...
» Associations between antibiotic use and outcomes in patients hospitalized with community-acquired pneumonia and positive respiratory viral assays
10/12/25 19:00 from sars-cov-2
CONCLUSIONS: Antibacterial use for patients with possible CAP and respiratory viruses is highly variable but outcomes are similar with 0-2 vs 5-7 days of antibacterials. This suggests antibiotics are not beneficial in most CAP patients w...
» Integrative Multi-Omics Analysis Reveals Age-Associated Molecular Mechanisms in SARS-CoV-2 Infection
10/12/25 19:00 from coronavirus
The COVID-19 pandemic has disproportionately affected elderly individuals, who exhibit higher risks of severe disease and mortality. Although the precise molecular mechanisms underlying this disparity remain unclear, we employed an integ...
» Diarrhoeal admissions among children aged <5 years in public sector facilities in Western Cape Province, South Africa, before and during the COVID-19 pandemic (2019 - 2021)
10/12/25 19:00 from coronavirus
CONCLUSION: There was a marked reduction in diarrhoea admissions during the strictest PHSM implementation. Interventions such as hand hygiene and physical distancing likely contributed to these observed changes. This study underscores th...
» Integrative Multi-Omics Analysis Reveals Age-Associated Molecular Mechanisms in SARS-CoV-2 Infection
10/12/25 19:00 from sars-cov-2
The COVID-19 pandemic has disproportionately affected elderly individuals, who exhibit higher risks of severe disease and mortality. Although the precise molecular mechanisms underlying this disparity remain unclear, we employed an integ...
» Diarrhoeal admissions among children aged <5 years in public sector facilities in Western Cape Province, South Africa, before and during the COVID-19 pandemic (2019 - 2021)
10/12/25 19:00 from sars-cov-2
CONCLUSION: There was a marked reduction in diarrhoea admissions during the strictest PHSM implementation. Interventions such as hand hygiene and physical distancing likely contributed to these observed changes. This study underscores th...
» Access to oncology care in western KwaZulu-Natal Province before, during and after the COVID-19 pandemic
10/12/25 19:00 from coronavirus
CONCLUSION: Despite the challenges of a global pandemic, access to GHOD care was not compromised in terms of patient waiting times. The absolute number of patients seen decreased, however, particularly those referred from primary care fa...
» An adenovirus-vectored recombinant vaccine confers passive immunity protection from swine acute diarrhea syndrome coronavirus challenge in neonatal mice
10/12/25 19:00 from Coronavirus origins
Swine Acute Diarrhea Syndrome Coronavirus (SADS-CoV), an emerging bat-origin Alphacoronavirus with demonstrated zoonotic potential, poses a significant threat to swine health and has considerable economic implications. Currently, no lice...
» Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025
10/12/25 19:00 from Coronavirus origins
During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 p...
» Analyzing global research trends in hepatology during Coronavirus Disease 2019: a bibliometric analysis
10/12/25 19:00 from Coronavirus origins
CONCLUSION: Top articles in our analysis focused on liver transplantation, pathophysiology, and healthcare management. It can aid researchers in assessing the effectiveness of different treatment modalities for hepatic impairment in COVI...
» From Spike to Strike: SARS-CoV-2 mRNA Vaccines Sensitise Tumours to PD-1/PD-L1 Blockade
10/12/25 19:00 from sars-cov-2 spike protein
This letter comments on work by Grippin et al. demonstrating that SARS-CoV-2 mRNA vaccines can reprogram the tumour microenvironment and enhance PD-1/PD-L1 blockade, suggesting broader implications for mRNA-driven immune activation in ca...
» Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1
10/12/25 19:00 from sars-cov-2 spike protein
KP.3.1.1 became a dominant successor to JN.1 by the second half of 2024 but the intrinsic pathogenicity and virological feature of KP.3.1.1 remain incompletely understood. Here, we comprehensively evaluated the pathogenesis and character...
» Effectiveness comparison of nirmatrelvir/ritonavir versus molnupiravir in COVID-19 patients with comorbidities in Taiwan: a multi-centre electronic health record study
10/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: Data revealed that both nirmatrelvir/ritonavir and molnupiravir demonstrated clinical benefits in treating COVID-19 patients in a real-world setting. Moreover, nirmatrelvir/ritonavir was associated with a lower risk of morta...
» Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1
10/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
KP.3.1.1 became a dominant successor to JN.1 by the second half of 2024 but the intrinsic pathogenicity and virological feature of KP.3.1.1 remain incompletely understood. Here, we comprehensively evaluated the pathogenesis and character...
» Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025
10/12/25 19:00 from Sars-Cov-2 origins
During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 p...
» Invention, innovation, and commercialisation in British biophysics
10/12/25 19:00 from sars-cov-2 spike protein
British biophysics has a tradition of scientific invention and innovation, resulting in new technologies transforming biological insight, such as rapid DNA sequencing, super-resolution and label-free microscopy, high-throughput and singl...
» Comparative evaluation of five rapid PCR platforms for respiratory virus detection
10/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSION: Among four platforms, the M10 (30-min version) and Flash10 platforms demonstrated the highest agreement rates with the GeneXpert. The variability in performance highlights the importance of independent platform evaluation.
» Analyzing global research trends in hepatology during Coronavirus Disease 2019: a bibliometric analysis
10/12/25 19:00 from Sars-Cov-2 origins
CONCLUSION: Top articles in our analysis focused on liver transplantation, pathophysiology, and healthcare management. It can aid researchers in assessing the effectiveness of different treatment modalities for hepatic impairment in COVI...
» AI tools aim to speed up outbreak modeling
10/12/25 19:00 from covid-19 and viral hemorrhagic fevers
DARPA program could help researchers build transparent, editable models of viral spread in days instead of weeks.
» An adenovirus-vectored recombinant vaccine confers passive immunity protection from swine acute diarrhea syndrome coronavirus challenge in neonatal mice
10/12/25 19:00 from Covid-19 origins
Swine Acute Diarrhea Syndrome Coronavirus (SADS-CoV), an emerging bat-origin Alphacoronavirus with demonstrated zoonotic potential, poses a significant threat to swine health and has considerable economic implications. Currently, no lice...
» Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025
10/12/25 19:00 from Covid-19 origins
During September 2023-August 2024, approximately 38,000 COVID-19-associated hospitalizations occurred among children and adolescents aged <18 years in the United States, a rate of approximately 53 per 100,000 children, ranging from 600 p...
» A comprehensive longitudinal analysis of the cellular immune response specific to the spike protein in healthcare workers vaccinated against SARS-CoV-2- ORCHESTRA Project
10/12/25 19:00 from sars-cov-2 spike protein
INTRODUCTION: The long-term dynamics of T-cell immunity following SARS-CoV-2 vaccination, essential for durable protection, remain incompletely understood. This study, therefore, aimed to investigate the kinetics and persistence of spike...
» Analyzing global research trends in hepatology during Coronavirus Disease 2019: a bibliometric analysis
10/12/25 19:00 from Covid-19 origins
CONCLUSION: Top articles in our analysis focused on liver transplantation, pathophysiology, and healthcare management. It can aid researchers in assessing the effectiveness of different treatment modalities for hepatic impairment in COVI...
» Garlic-Derived Phytochemical Candidates Predicted to Disrupt SARS-CoV-2 RBD-ACE2 Binding and Inhibit Viral Entry
10/12/25 19:00 from sars-cov-2 spike protein
The emergence of SARS-CoV-2 and its rapid global spread underscores the urgent need for novel therapeutic strategies. This study investigates the antiviral potential of Allium sativum (garlic) extracts against SARS-CoV-2, focusing on dis...
» Post-exposure prevention in Marburg virus outbreaks: potential role of remdesivir in emergency response
10/12/25 19:00 from covid-19 and viral hemorrhagic fevers
Marburg virus (MARV), a close relative of the Ebola virus, causes severe hemorrhagic fevers with a case fatality rate of up to 88%. In the absence of specific treatment or vaccine, its rapid spread through epidemics in Africa, particular...
» In Silico Analysis of C60 Fullerene Interaction with TMPRSS2: Toward Novel COVID-19 Prevention Approaches
10/12/25 19:00 from sars-cov-2 spike protein
The recent global spread of the SARS-CoV-2 pathogen, which causes COVID-19, and its rapid mutation, requires the fast development of effective preventive and treatment measures. According to WHO reports, over 778 million confirmed cases ...
» Specific Instability of HLA-A*03:01 Expression in HEK-293 Cells
10/12/25 19:00 from sars-cov-2 spike protein
HEK-293 is a highly transfectable human cell line widely used as a model for protein expression. Since large amounts of cells are often required for the purification of HLA immunopeptidomes, suspension-growing variants, such as HEK-293F,...
» Hybrid dielectric-graphene nanostructured SERS substrates for antibody sensing
09/12/25 19:00 from sars-cov-2
We present a hybrid surface-enhanced Raman spectroscopy (SERS) platform based on a nanostructured silicon substrate integrated with functionalized graphene for the selective detection of biomolecules such as prolactin and SARS-CoV-2 anti...
» The effects of stress on political leadership evaluations
09/12/25 19:00 from coronavirus
Stress is a response to external environmental conditions that encourages individuals to pursue changes in their lives. We examine the relationship between stress and federal and provincial political leaders' approval ratings. We theoriz...
» T-Cell Interferon Gamma Responses to SARS-CoV-2 Following Infection with/Without Vaccination in a Tanzanian Population
09/12/25 19:00 from sars-cov-2
CONCLUSION: Strong and possibly cross-reactive T-cell responses to SARS-CoV-2 were detected in Tanzanian individuals following infection with/without vaccination. Moreover, high plasma IFN-γ levels were detected, especially among partici...
» Maternal and Fetal Outcomes in Pregnant Women Admitted to the Intensive Care Unit with A/H1N1pdm or SARS-CoV-2 Infection: A Retrospective Study
09/12/25 19:00 from sars-cov-2
CONCLUSION: Respiratory failure due to A/H1N1pdm and SARS-CoV-2 infections in pregnancy is associated with high maternal mortality and fetal loss. Delayed presentation is independently associated with maternal death.
» Hospice and Palliative Care Response Policy During the Coronavirus Disease 2019 (COVID-19) Pandemic in South Korea
09/12/25 19:00 from coronavirus
South Korea received international acclaim for its rapid response to the initial coronavirus disease 2019 (COVID-19) pandemic crisis through the "K-Quarantine" model, successfully managing it without closing its borders; however, termina...
» The effects of stress on political leadership evaluations
09/12/25 19:00 from covid-19
Stress is a response to external environmental conditions that encourages individuals to pursue changes in their lives. We examine the relationship between stress and federal and provincial political leaders' approval ratings. We theoriz...
» The long-term effects of COVID-19 on oxygen carrying capacity in adults at the University of Limpopo, South Africa
09/12/25 19:00 from sars-cov-2
CONCLUSION: COVID-19 patients in this study experienced persistent symptoms, but most of the participants had no symptoms at the time the study was conducted. Diet might have had an impact on Hb and Hct in the COVID-19 non-naive male pop...
» Features associated with 90-day in-person follow-up care after virtual visits in urology
09/12/25 19:00 from coronavirus
CONCLUSIONS: Patients with a shorter travel distance and those being seen for a vasectomy were more likely to pursue in-person care within 90 days after a telehealth visit than those seen for oncologic indications. These findings may be ...
» Impact of COVID-19 on Adaptive Skills and Psychiatric Symptoms in South Korean Children With Autism Spectrum Disorder
09/12/25 19:00 from coronavirus
CONCLUSION: The majority of South Korean children with ASD demonstrated stability despite the lack of consistency or structure during the pandemic. A 2-year longitudinal follow-up study is underway.
» Multiplex Magnetic Biosensor Microarrays Facilitate Personalized Vaccination Schedules for SARS-CoV-2 Variants
09/12/25 19:00 from sars-cov-2
Rapid, sensitive, multiplexed antibody detection technologies are essential for assessing vaccine efficacy and recipient immunity against viruses. As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continue to emerg...
» Poverty and Ethnic Patterns in COVID-19 Excess Mortality: Evidence from Chile, 2020-2022
09/12/25 19:00 from covid-19
The COVID-19 pandemic highlighted deep-rooted health inequities globally, with marginalized populations showing disproportionate disease burden. We employed Serfling regression models and multivariable analyses to estimate excess mortali...
» Mixed-methods study assessing the acceptability and feasibility of Human Challenge Studies for Disease X in Healthy UK Adults in a SARS-CoV-2 pandemic setting
09/12/25 19:00 from sars-cov-2
CONCLUSIONS: Vaccine trial participants are an informed and motivated public group who can provide situated public expertise for CHIS pandemic preparedness. Recruitment to CHIS in a pandemic may be more efficient if targeted to younger, ...
» Hybrid dielectric-graphene nanostructured SERS substrates for antibody sensing
09/12/25 19:00 from covid-19
We present a hybrid surface-enhanced Raman spectroscopy (SERS) platform based on a nanostructured silicon substrate integrated with functionalized graphene for the selective detection of biomolecules such as prolactin and SARS-CoV-2 anti...
» Unmasking and Addressing COVID-19-Related Maladaptive Grief Reactions Among Suicidal Youth: Pilot Evidence for an Enhanced Psychiatry Emergency Room Safety Preventive Intervention
09/12/25 19:00 from coronavirus
CONCLUSION: This study suggests the feasibility and potential effectiveness of providing a grief-enhanced trauma-informed safety preventive intervention in a PER. This intervention was associated with reducing severity of maladaptive gri...
» A surge in fulminant idiopathic intracranial hypertension cases within 1 year from the coronavirus disease 2019 pandemic lockdown: A case series
09/12/25 19:00 from coronavirus
CONCLUSION: There has been a recent surge in the number of cases of fulminant IIH in the COVID-19 lockdown period. The negative impact of COVID-19 on health led to an increase in weight, which is thought to have played a role in this rec...
» A compartmental model of variant coexistence, dynamics and dominance in infectious diseases: Case for SARS-CoV-2 in Abu Dhabi
09/12/25 19:00 from sars-cov-2
In recent years, the rapid mutation of SARS-CoV-2 has led to the emergence of new variants. Despite advancements in pandemic control, these new variants could pose substantial public health issues. This study introduces a comprehensive c...
» Progressive Multifocal Leukoencephalopathy after Administration of Front-Line Obinutuzumab and Venetoclax in a Patient with Chronic Lymphocytic Leukemia: Case Report
09/12/25 19:00 from covid-19
CONCLUSION: PML is a rare complication of anti-CD 20 monoclonal antibodies, including obinutuzumab. Early recognition of PML is essential to discontinue an affecting drug and initiate therapy.
» Evaluating the Sustaining Play, Sustaining Health programme in Australian early childhood education and care services: a pilot randomized controlled trial
09/12/25 19:00 from sars-cov-2
Early childhood education and care (ECEC) services are a recommended setting to deliver interventions improving children's physical activity (PA). Indoor-outdoor free play, where children move freely between indoor-outdoor environments, ...
» Hospice and Palliative Care Response Policy During the Coronavirus Disease 2019 (COVID-19) Pandemic in South Korea
09/12/25 19:00 from covid-19
South Korea received international acclaim for its rapid response to the initial coronavirus disease 2019 (COVID-19) pandemic crisis through the "K-Quarantine" model, successfully managing it without closing its borders; however, termina...
» IL-10- and IL-13-Biased T Cell Responses to SARS-CoV-2 Vaccination in Diabetes
09/12/25 19:00 from sars-cov-2
Type 1 and type 2 diabetes are associated with increased severity and mortality from respiratory virus infections. Vaccination in the general population significantly reduces the risk of severe respiratory viral infection and triggers a ...
» T-Cell Interferon Gamma Responses to SARS-CoV-2 Following Infection with/Without Vaccination in a Tanzanian Population
09/12/25 19:00 from covid-19
CONCLUSION: Strong and possibly cross-reactive T-cell responses to SARS-CoV-2 were detected in Tanzanian individuals following infection with/without vaccination. Moreover, high plasma IFN-γ levels were detected, especially among partici...
» Virtual Pet-Assisted Therapy to Alleviate Symptoms of Long COVID: A Prospective Pilot Interventional Study
09/12/25 19:00 from sars-cov-2
BACKGROUND Post-COVID-19 condition (long COVID) is characterized by persistent symptoms following acute infection. Given the limited efficacy of pharmacologic treatments, there is growing interest in complementary, non-contact interventi...
» Maternal and Fetal Outcomes in Pregnant Women Admitted to the Intensive Care Unit with A/H1N1pdm or SARS-CoV-2 Infection: A Retrospective Study
09/12/25 19:00 from covid-19
CONCLUSION: Respiratory failure due to A/H1N1pdm and SARS-CoV-2 infections in pregnancy is associated with high maternal mortality and fetal loss. Delayed presentation is independently associated with maternal death.
» The influence of recent COVID-19 infection on patients undergoing thyroid surgery: Clinical outcomes and patient perception observations
09/12/25 19:00 from sars-cov-2
Our research observed the condition and potential surgical risks of patients who have previously contracted coronavirus disease 2019 (COVID-19) and subsequently underwent thyroid surgery. A research cohort of 140 patients undergoing thyr...
» Recurrent severe COVID-19 with Good's syndrome in a patient after thymoma surgery: A case report
09/12/25 19:00 from sars-cov-2
RATIONALE: Good's syndrome (GS) is a rare adult-onset immunodeficiency characterized by the coexistence of thymoma and profound defects in both humoral and cellular immunity. Because of these immune abnormalities, patients are highly vul...
» The long-term effects of COVID-19 on oxygen carrying capacity in adults at the University of Limpopo, South Africa
09/12/25 19:00 from covid-19
CONCLUSION: COVID-19 patients in this study experienced persistent symptoms, but most of the participants had no symptoms at the time the study was conducted. Diet might have had an impact on Hb and Hct in the COVID-19 non-naive male pop...
» Multiplex Magnetic Biosensor Microarrays Facilitate Personalized Vaccination Schedules for SARS-CoV-2 Variants
09/12/25 19:00 from coronavirus
Rapid, sensitive, multiplexed antibody detection technologies are essential for assessing vaccine efficacy and recipient immunity against viruses. As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continue to emerg...
» Evolving trends in medical trainee wellbeing research from 2014 to 2023: A bibliometric analysis
09/12/25 19:00 from sars-cov-2
CONCLUSIONS: The research landscape on medical trainee wellbeing is evolving and was significantly reshaped by COVID-19. Emerging topics such as narrative medicine and professionalism reflect a shift towards comprehensive approaches. Fut...
» Features associated with 90-day in-person follow-up care after virtual visits in urology
09/12/25 19:00 from covid-19
CONCLUSIONS: Patients with a shorter travel distance and those being seen for a vasectomy were more likely to pursue in-person care within 90 days after a telehealth visit than those seen for oncologic indications. These findings may be ...
» Long-term trends in anemia prevalence before and after COVID-19 among non-pregnant adults in South Korea, 2010 to 2023
09/12/25 19:00 from sars-cov-2
Anemia is a global public health concern, yet its long-term trends in the general adult population, particularly during the COVID-19 pandemic, remain unclear. This study analyzed long-term trends and risk factors for anemia among non-pre...
» Early identification of abnormal pulmonary infectious diseases using unsupervised anomaly detection
09/12/25 19:00 from coronavirus
CONCLUSIONS: This work offers a robust solution for the early identification of both known and emerging APIDs. The developed LRAE showed remarkable performance in detecting abnormal PICT image sequences.
» Telemedicine: a substitute or complement for home-based medical care? the experience of Medicare enrollees with dementia
09/12/25 19:00 from covid-19
CONCLUSION: These findings suggest that Medicare's telemedicine waivers expanded, rather than replaced, HBMC. Sustaining these policies may support aging in place for individuals with dementia, though disparities in access remain a criti...
» Analysis of bibliometric and cross-cycle NHANES data: The effects of physical activity and vitamin D on pubertal onset in children aged 6-14 and the differences before and after the pandemic
09/12/25 19:00 from sars-cov-2
This study integrates bibliometric analysis with pre- and post-pandemic data from National Health and Nutrition Examination Survey cycles to examine the interrelationships between physical activity (PA), 25-hydroxyvitamin D (25(OH)D) lev...
» Weighted negative binomial distribution: properties and applications
09/12/25 19:00 from covid-19
Here we consider a weighted version of the negative binomial distribution and illustrate its usefulness through fitting Covid-19 datasets. We obtain several important properties of the distribution such as probability generating function...
» Switch from Intravenous to Subcutaneous Formulation of Tocilizumab in Rheumatoid Arthritis: Retrospective Cohort Analysis and Systematic Literature Review
09/12/25 19:00 from coronavirus
CONCLUSION: Intravenous to subcutaneous tocilizumab switch is an effective and safe option in rheumatoid arthritis management, especially in the case of a shared decision.
» A Systematic Review of Emotional, Cognitive, and Logistical Factors Influencing Simulated Patient Performance in Simulation-Based Education
09/12/25 19:00 from covid-19
CONCLUSION: Authentic SP portrayals enhance student learning, but factors such as emotional strain and cognitive load can limit effectiveness. We recommend structured SP training, robust feedback mechanisms, and attention to SP cognitive...
» Evaluating the Sustaining Play, Sustaining Health programme in Australian early childhood education and care services: a pilot randomized controlled trial
09/12/25 19:00 from coronavirus
Early childhood education and care (ECEC) services are a recommended setting to deliver interventions improving children's physical activity (PA). Indoor-outdoor free play, where children move freely between indoor-outdoor environments, ...
» Ethnicity and sub-Saharan African representation in the emergency development of covid-19 vaccines
09/12/25 19:00 from covid-19
No abstract
» Label-free visualization and quantitative analysis of Far UV-C skin safety with dynamic optical coherence tomography with subcellular resolution
09/12/25 19:00 from covid-19
The recent COVID-19 pandemic sparked interest in interventional public health measures like ultraviolet germicidal irradiation (UVGI) of occupied spaces with the development of Far UV-C (200-230 nm) emitting sources promising similar ant...
» IL-10- and IL-13-Biased T Cell Responses to SARS-CoV-2 Vaccination in Diabetes
09/12/25 19:00 from coronavirus
Type 1 and type 2 diabetes are associated with increased severity and mortality from respiratory virus infections. Vaccination in the general population significantly reduces the risk of severe respiratory viral infection and triggers a ...
» Seeking Care for Suicidal Thoughts and Actions: How COVID Affected Our Pediatric Patients
09/12/25 19:00 from covid-19
CONCLUSION: In the pandemic time period, there were significantly more patient presentations for suicidal ideation and intentional self-harm than would have been expected based on pre-pandemic patterns. This volume has continued up to 2 ...
» Virtual Pet-Assisted Therapy to Alleviate Symptoms of Long COVID: A Prospective Pilot Interventional Study
09/12/25 19:00 from coronavirus
BACKGROUND Post-COVID-19 condition (long COVID) is characterized by persistent symptoms following acute infection. Given the limited efficacy of pharmacologic treatments, there is growing interest in complementary, non-contact interventi...
» The influence of recent COVID-19 infection on patients undergoing thyroid surgery: Clinical outcomes and patient perception observations
09/12/25 19:00 from coronavirus
Our research observed the condition and potential surgical risks of patients who have previously contracted coronavirus disease 2019 (COVID-19) and subsequently underwent thyroid surgery. A research cohort of 140 patients undergoing thyr...
» Recurrent severe COVID-19 with Good's syndrome in a patient after thymoma surgery: A case report
09/12/25 19:00 from coronavirus
RATIONALE: Good's syndrome (GS) is a rare adult-onset immunodeficiency characterized by the coexistence of thymoma and profound defects in both humoral and cellular immunity. Because of these immune abnormalities, patients are highly vul...
» Evolving trends in medical trainee wellbeing research from 2014 to 2023: A bibliometric analysis
09/12/25 19:00 from coronavirus
CONCLUSIONS: The research landscape on medical trainee wellbeing is evolving and was significantly reshaped by COVID-19. Emerging topics such as narrative medicine and professionalism reflect a shift towards comprehensive approaches. Fut...
» Post-quadri-vaccinal SARS-CoV-2 antibodies in Vietnamese patients with end-stage renal disease: A prospective cohort study
09/12/25 19:00 from sars-cov-2 spike protein
Patients with chronic kidney disease are at high risk for severe coronavirus disease 2019 (COVID-19). Although vaccination offers protection, antibody titers in this population decline over time. This study measured SARS-CoV-2 spike prot...
» FUNCTIONAL STATUS OF POST-COVID-19 PATIENTS IN KAZAKHSTAN
09/12/25 19:00 from coronavirus
CONCLUSION: Hospitalization was linked to impaired functional outcomes, yet persistent fatigue and dyspnea affected all patients, underscoring the need for comprehensive rehabilitation strategies for COVID-19 survivors in Kazakhstan.
» US Views on New Vaccine Development and False Information After COVID-19
09/12/25 19:00 from coronavirus
Vaccine innovations offer key tools to protect health, yet public views about vaccine development in the wake of COVID-19 are not well understood. We conducted a nationally representative survey of 1,632 US adults to examine public perce...
» Leveraging Systems-of-Systems Analysis to Strengthen Epidemic Intelligence for Preparedness and Response
09/12/25 19:00 from coronavirus
The COVID-19 pandemic exposed significant gaps in the coordination and integration of efforts required to effectively manage large-scale infectious disease outbreaks. A successful response to such crises demands the swift and ongoing syn...
» Establishment of Subnational Public Health Emergency Operation Centers During the COVID-19 Pandemic, Kenya, 2020-2023
09/12/25 19:00 from coronavirus
The World Health Organization (WHO) assessment of the implementation status of national public health emergency operation center (PHEOCs) showed that African countries have made considerable efforts in setting up PHEOCs at national level...
» Managing COVID-19 care in the pandemic context: impact of family health coverage
09/12/25 19:00 from coronavirus
CONCLUSIONS: the teams reorganized and restructured services during the critical period of the pandemic, strengthening family health as the main service of Primary Health Care.
» Perception of quality of life and emotional disorders in Brazilian nursing during COVID-19
09/12/25 19:00 from coronavirus
CONCLUSIONS: personal and institutional work conditions have impacted the mental health and quality of life of Brazilian nurses.
» Comparing COVID-19 Variants in Children Hospitalized for Concern of Tracheostomy-associated Infection: A Multicenter Prospective Cohort Study
09/12/25 19:00 from covid-19
In this ancillary study of a larger, prospective cohort study, we sought to compare presentation and outcomes of COVID-19 infections by variant (alpha, delta, and omicron) in 103 children with tracheostomy (108 admissions) hospitalized f...
» Association between social environment and birth weight during the COVID-19 pandemic in a Brazilian metropolis
09/12/25 19:00 from coronavirus
CONCLUSION: The findings show that both individual and contextual determinants directly influenced birth weight during the pandemic, reinforcing the need for actions that integrate obstetric care and social policies aimed at reducing ine...
» Tuberculosis detection actions in Primary Health Care during the COVID-19 pandemic
09/12/25 19:00 from coronavirus
CONCLUSIONS: the repercussions of the pandemic on tuberculosis detection measures are highlighted, which had an impact on the epidemiological data of the disease in the municipality.
» Inhibition of CXCL10 and IFN-γ ameliorates myocarditis in preclinical models of SARS-CoV-2 mRNA vaccination
09/12/25 19:00 from coronavirus
Messenger RNA (mRNA) vaccines against SARS-CoV-2 are highly effective and were instrumental in curbing the COVID-19 pandemic. However, rare cases of noninfective myocarditis, particularly in young males and typically after the second dos...
» Lessons Learned From the COVID-19 Pandemic: "Those Who Cannot Remember the Past Are Condemned to Repeat It"
09/12/25 19:00 from covid-19
No abstract
» Creating a Research-Ready Data Asset version of primary care data for Wales and investigating the impact of COVID-19 on utilisation of primary care services
09/12/25 19:00 from coronavirus
CONCLUSIONS: The WLGP RRDA improves the usability of primary care data, supporting timely, scalable analysis of healthcare delivery and system-level trends.
» FUNCTIONAL STATUS OF POST-COVID-19 PATIENTS IN KAZAKHSTAN
09/12/25 19:00 from covid-19
CONCLUSION: Hospitalization was linked to impaired functional outcomes, yet persistent fatigue and dyspnea affected all patients, underscoring the need for comprehensive rehabilitation strategies for COVID-19 survivors in Kazakhstan.
» US Views on New Vaccine Development and False Information After COVID-19
09/12/25 19:00 from covid-19
Vaccine innovations offer key tools to protect health, yet public views about vaccine development in the wake of COVID-19 are not well understood. We conducted a nationally representative survey of 1,632 US adults to examine public perce...
» Investigation on the knowledge-attitude-practice of medical students in controlling emerging infectious diseases: A case study of COVID-19
09/12/25 19:00 from coronavirus
CONCLUSIONS: Altogether, medical students possess certain basic knowledge in controlling emerging infectious diseases, but some still generally suffer from insufficient cognitive depth and anxiety. Colleges can systematically enhance stu...
» Exploring the Impact of Prerequisite eLearning on Respiratory Protection Equipment Safety Behaviors in Simulation Training
09/12/25 19:00 from covid-19
Military healthcare workers (HCWs) face similar clinical challenges in providing care during the pandemic as the civilian workforce. The most common respirator used in healthcare is the N95 filtering facepiece respirator (FFR). Video sco...
» The relationship between lay beliefs about the world and pandemic-related beliefs, attitudes, and behaviors
09/12/25 19:00 from coronavirus
The Covid-19 pandemic created a strong need to understand how people can be motivated to engage in protective health behaviors (such as vaccination). Past research suggests that perceiving a health threat as serious and protective behavi...
» Leveraging Systems-of-Systems Analysis to Strengthen Epidemic Intelligence for Preparedness and Response
09/12/25 19:00 from covid-19
The COVID-19 pandemic exposed significant gaps in the coordination and integration of efforts required to effectively manage large-scale infectious disease outbreaks. A successful response to such crises demands the swift and ongoing syn...
» FUNCTIONAL STATUS OF POST-COVID-19 PATIENTS IN KAZAKHSTAN
09/12/25 19:00 from sars-cov-2
CONCLUSION: Hospitalization was linked to impaired functional outcomes, yet persistent fatigue and dyspnea affected all patients, underscoring the need for comprehensive rehabilitation strategies for COVID-19 survivors in Kazakhstan.
» Group-Sequential Designs With an Externally-Driven Change of Primary Endpoint
09/12/25 19:00 from coronavirus
Clinical trials conducted during the COVID-19 pandemic demonstrated the value of adaptive design methods in emerging disease settings, when there can be considerable uncertainty around disease natural history, anticipated endpoint effect...
» Establishment of Subnational Public Health Emergency Operation Centers During the COVID-19 Pandemic, Kenya, 2020-2023
09/12/25 19:00 from covid-19
The World Health Organization (WHO) assessment of the implementation status of national public health emergency operation center (PHEOCs) showed that African countries have made considerable efforts in setting up PHEOCs at national level...
» Awake Prone Positioning in Patients With COVID-19 Respiratory Failure: A Randomized Clinical Trial
09/12/25 19:00 from coronavirus
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of nonintubated patients with COVID-19 and hypoxemic respiratory failure, daily APP of 6 hours showed a high probability of reduced endotracheal intubation and/or death over a ...
» Managing COVID-19 care in the pandemic context: impact of family health coverage
09/12/25 19:00 from covid-19
CONCLUSIONS: the teams reorganized and restructured services during the critical period of the pandemic, strengthening family health as the main service of Primary Health Care.
» US Views on New Vaccine Development and False Information After COVID-19
09/12/25 19:00 from sars-cov-2
Vaccine innovations offer key tools to protect health, yet public views about vaccine development in the wake of COVID-19 are not well understood. We conducted a nationally representative survey of 1,632 US adults to examine public perce...
» Perception of quality of life and emotional disorders in Brazilian nursing during COVID-19
09/12/25 19:00 from covid-19
CONCLUSIONS: personal and institutional work conditions have impacted the mental health and quality of life of Brazilian nurses.
» Association between social environment and birth weight during the COVID-19 pandemic in a Brazilian metropolis
09/12/25 19:00 from covid-19
CONCLUSION: The findings show that both individual and contextual determinants directly influenced birth weight during the pandemic, reinforcing the need for actions that integrate obstetric care and social policies aimed at reducing ine...
» Leveraging Systems-of-Systems Analysis to Strengthen Epidemic Intelligence for Preparedness and Response
09/12/25 19:00 from sars-cov-2
The COVID-19 pandemic exposed significant gaps in the coordination and integration of efforts required to effectively manage large-scale infectious disease outbreaks. A successful response to such crises demands the swift and ongoing syn...
» Longitudinal Analysis of Respiratory Syncytial Virus in Children during and after COVID-19 Pandemic in China: Shifts in Seasonality and Disease Burden
09/12/25 19:00 from coronavirus
CONCLUSION: NPIs fundamentally reshaped RSV epidemiology, inducing seasonal shifts and redirecting disease burden toward older infants experiencing delayed primary infection due to "immune debt."
» Vascular reactivity in post-COVID-19 patients: analysis and correlation with functional capacity
09/12/25 19:00 from covid-19
No abstract
» Establishment of Subnational Public Health Emergency Operation Centers During the COVID-19 Pandemic, Kenya, 2020-2023
09/12/25 19:00 from sars-cov-2
The World Health Organization (WHO) assessment of the implementation status of national public health emergency operation center (PHEOCs) showed that African countries have made considerable efforts in setting up PHEOCs at national level...
» Shaping the Immune Response: Cathepsins in Virus-Dendritic Cell Interactions
09/12/25 19:00 from Cell entry mechanisms of SARS-CoV-2
Dendritic cells (DCs) are among the first immune cells to detect viral invasion and play a central role in initiating and shaping antiviral immune responses. Many innate and adaptive immune functions of DCs are regulated by cathepsins, p...
» Economic burden, mortality, and incidence of hospital admissions for cerebrovascular diseases in Brazil from 2017 to 2022: a perspective of the Brazilian Unified Health System
09/12/25 19:00 from covid-19
CONCLUSION: Mortality rates from cerebrovascular diseases decreased in Brazil, showing regional and age group variations and a worrying increase in young men. Despite stable hospitalizations, hospital costs significantly increased, indic...
» Managing COVID-19 care in the pandemic context: impact of family health coverage
09/12/25 19:00 from sars-cov-2
CONCLUSIONS: the teams reorganized and restructured services during the critical period of the pandemic, strengthening family health as the main service of Primary Health Care.
» Inequities in COVID-19 morbidity in Brazil: the influence of demographic and socioeconomic characteristics and preexisting health conditions
09/12/25 19:00 from covid-19
CONCLUSION: The findings revealed major socioeconomic inequalities across all indicators related to COVID-19 morbidity. Older age, preexisting health conditions, and Long COVID contributed to greater disease severity and increased hospit...
» Perception of quality of life and emotional disorders in Brazilian nursing during COVID-19
09/12/25 19:00 from sars-cov-2
CONCLUSIONS: personal and institutional work conditions have impacted the mental health and quality of life of Brazilian nurses.
» Tuberculosis detection actions in Primary Health Care during the COVID-19 pandemic
09/12/25 19:00 from covid-19
CONCLUSIONS: the repercussions of the pandemic on tuberculosis detection measures are highlighted, which had an impact on the epidemiological data of the disease in the municipality.
» Inhibition of CXCL10 and IFN-gamma ameliorates myocarditis in preclinical models of SARS-CoV-2 mRNA vaccination
09/12/25 19:00 from covid-19
Messenger RNA (mRNA) vaccines against SARS-CoV-2 are highly effective and were instrumental in curbing the COVID-19 pandemic. However, rare cases of noninfective myocarditis, particularly in young males and typically after the second dos...
» Association between social environment and birth weight during the COVID-19 pandemic in a Brazilian metropolis
09/12/25 19:00 from sars-cov-2
CONCLUSION: The findings show that both individual and contextual determinants directly influenced birth weight during the pandemic, reinforcing the need for actions that integrate obstetric care and social policies aimed at reducing ine...
» Tuberculosis detection actions in Primary Health Care during the COVID-19 pandemic
09/12/25 19:00 from sars-cov-2
CONCLUSIONS: the repercussions of the pandemic on tuberculosis detection measures are highlighted, which had an impact on the epidemiological data of the disease in the municipality.
» Inhibition of CXCL10 and IFN-gamma ameliorates myocarditis in preclinical models of SARS-CoV-2 mRNA vaccination
09/12/25 19:00 from sars-cov-2
Messenger RNA (mRNA) vaccines against SARS-CoV-2 are highly effective and were instrumental in curbing the COVID-19 pandemic. However, rare cases of noninfective myocarditis, particularly in young males and typically after the second dos...
» Creating a Research-Ready Data Asset version of primary care data for Wales and investigating the impact of COVID-19 on utilisation of primary care services
09/12/25 19:00 from sars-cov-2
CONCLUSIONS: The WLGP RRDA improves the usability of primary care data, supporting timely, scalable analysis of healthcare delivery and system-level trends.
» Investigation on the knowledge-attitude-practice of medical students in controlling emerging infectious diseases: A case study of COVID-19
09/12/25 19:00 from sars-cov-2
CONCLUSIONS: Altogether, medical students possess certain basic knowledge in controlling emerging infectious diseases, but some still generally suffer from insufficient cognitive depth and anxiety. Colleges can systematically enhance stu...
» The relationship between lay beliefs about the world and pandemic-related beliefs, attitudes, and behaviors
09/12/25 19:00 from sars-cov-2
The Covid-19 pandemic created a strong need to understand how people can be motivated to engage in protective health behaviors (such as vaccination). Past research suggests that perceiving a health threat as serious and protective behavi...
» Group-Sequential Designs With an Externally-Driven Change of Primary Endpoint
09/12/25 19:00 from sars-cov-2
Clinical trials conducted during the COVID-19 pandemic demonstrated the value of adaptive design methods in emerging disease settings, when there can be considerable uncertainty around disease natural history, anticipated endpoint effect...
» Awake Prone Positioning in Patients With COVID-19 Respiratory Failure: A Randomized Clinical Trial
09/12/25 19:00 from sars-cov-2
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of nonintubated patients with COVID-19 and hypoxemic respiratory failure, daily APP of 6 hours showed a high probability of reduced endotracheal intubation and/or death over a ...
» Longitudinal Analysis of Respiratory Syncytial Virus in Children during and after COVID-19 Pandemic in China: Shifts in Seasonality and Disease Burden
09/12/25 19:00 from sars-cov-2
CONCLUSION: NPIs fundamentally reshaped RSV epidemiology, inducing seasonal shifts and redirecting disease burden toward older infants experiencing delayed primary infection due to "immune debt."
» Improving directed evolution strategies: error-prone PCR optimization for SARS-CoV-2 spike receptor binding domain
09/12/25 19:00 from sars-cov-2 spike protein
CONCLUSION: Our results highlight the virulence-enhancing potential of mutations and enable researchers to evaluate potential vaccine candidates in the future. Furthermore, compared to earlier reports, the method described here requires ...
» Post-quadri-vaccinal SARS-CoV-2 antibodies in Vietnamese patients with end-stage renal disease: A prospective cohort study
09/12/25 19:00 from sars-cov-2 spike protein
Patients with chronic kidney disease are at high risk for severe coronavirus disease 2019 (COVID-19). Although vaccination offers protection, antibody titers in this population decline over time. This study measured SARS-CoV-2 spike prot...
» A comparison of allied healthcare versus no allied healthcare on participation, fatigue, physical functioning and health-related quality of life for patients with persistent complaints after a COVID-19 infection
09/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: Patients with persistent complaints after a COVID-19 infection showed significantly lower participation after 6 months, higher health-related quality of life after 12 months, and better physical functioning after 6 and 12 mo...
» Diagnostic delay inducing severe imported falciparum malaria: a time-sensitivity comparison of two imported cases during COVID-19 co-circulation
09/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: Diagnostic delay directly impacts severe malaria risk during COVID-19 co-circulation. Parallel testing for both pathogens in febrile travelers from endemic areas is critical. The proposed "48-Hour Three-Tier Diagnostic Respo...
» Shaping the Immune Response: Cathepsins in Virus-Dendritic Cell Interactions
09/12/25 19:00 from Cell entry mechanisms of SARS-CoV-2
Dendritic cells (DCs) are among the first immune cells to detect viral invasion and play a central role in initiating and shaping antiviral immune responses. Many innate and adaptive immune functions of DCs are regulated by cathepsins, p...
» Improving directed evolution strategies: error-prone PCR optimization for SARS-CoV-2 spike receptor binding domain
09/12/25 19:00 from sars-cov-2 spike protein
CONCLUSION: Our results highlight the virulence-enhancing potential of mutations and enable researchers to evaluate potential vaccine candidates in the future. Furthermore, compared to earlier reports, the method described here requires ...
» Post-quadri-vaccinal SARS-CoV-2 antibodies in Vietnamese patients with end-stage renal disease: A prospective cohort study
09/12/25 19:00 from sars-cov-2 spike protein
Patients with chronic kidney disease are at high risk for severe coronavirus disease 2019 (COVID-19). Although vaccination offers protection, antibody titers in this population decline over time. This study measured SARS-CoV-2 spike prot...
» A comparison of allied healthcare versus no allied healthcare on participation, fatigue, physical functioning and health-related quality of life for patients with persistent complaints after a COVID-19 infection
09/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: Patients with persistent complaints after a COVID-19 infection showed significantly lower participation after 6 months, higher health-related quality of life after 12 months, and better physical functioning after 6 and 12 mo...
» Shaping the Immune Response: Cathepsins in Virus-Dendritic Cell Interactions
09/12/25 19:00 from Cell entry mechanisms of SARS-CoV-2
Dendritic cells (DCs) are among the first immune cells to detect viral invasion and play a central role in initiating and shaping antiviral immune responses. Many innate and adaptive immune functions of DCs are regulated by cathepsins, p...
» Diagnostic delay inducing severe imported falciparum malaria: a time-sensitivity comparison of two imported cases during COVID-19 co-circulation
09/12/25 19:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: Diagnostic delay directly impacts severe malaria risk during COVID-19 co-circulation. Parallel testing for both pathogens in febrile travelers from endemic areas is critical. The proposed "48-Hour Three-Tier Diagnostic Respo...
» Improving directed evolution strategies: error-prone PCR optimization for SARS-CoV-2 spike receptor binding domain
09/12/25 19:00 from sars-cov-2 spike protein
CONCLUSION: Our results highlight the virulence-enhancing potential of mutations and enable researchers to evaluate potential vaccine candidates in the future. Furthermore, compared to earlier reports, the method described here requires ...
» Post-quadri-vaccinal SARS-CoV-2 antibodies in Vietnamese patients with end-stage renal disease: A prospective cohort study
09/12/25 19:00 from sars-cov-2 spike protein
Patients with chronic kidney disease are at high risk for severe coronavirus disease 2019 (COVID-19). Although vaccination offers protection, antibody titers in this population decline over time. This study measured SARS-CoV-2 spike prot...
» Persistence of SARS-CoV-2 S IgG Antibodies in Children Post-COVID-19 and the Association of Antibody Levels with Vaccination Status
08/12/25 19:00 from sars-cov-2
Children who contracted COVID-19 develop antibodies targeting the SARS-CoV-2 spike (S) protein which persist for 4 to 12 months following infection. We sought to analyze the antibody response to SARS-CoV-2 one year after COVID-19 in chil...
» Persistence of SARS-CoV-2 S IgG Antibodies in Children Post-COVID-19 and the Association of Antibody Levels with Vaccination Status
08/12/25 19:00 from coronavirus
Children who contracted COVID-19 develop antibodies targeting the SARS-CoV-2 spike (S) protein which persist for 4 to 12 months following infection. We sought to analyze the antibody response to SARS-CoV-2 one year after COVID-19 in chil...
» Clinical Presentation of Pediatric Mycoplasma pneumoniae Before and After the COVID-19 Pandemic
08/12/25 19:00 from coronavirus
CONCLUSIONS: Pediatric MP presentation in 2024 differed notably from prior epidemics, marked by increased severe pneumonia in older children. Enhanced awareness facilitated rapid diagnostics, reducing hospital admissions, unnecessary tes...
» Risk of hospitalisation and mortality among patients with interstitial lung disease and COVID-19: A French multicentre prospective cohort
08/12/25 19:00 from sars-cov-2
CONCLUSIONS: Poor outcomes related to COVID-19 are associated with ILD subtype and severity, background glucocorticoid therapy and absence of vaccination. There is no evidence of late mortality.
» Risk of hospitalisation and mortality among patients with interstitial lung disease and COVID-19: A French multicentre prospective cohort
08/12/25 19:00 from coronavirus
CONCLUSIONS: Poor outcomes related to COVID-19 are associated with ILD subtype and severity, background glucocorticoid therapy and absence of vaccination. There is no evidence of late mortality.
» In Silico Exploration of Potential Inhibitors Targeting SARS-CoV-2 Non-Structural Protein 15 (Nsp15): A Comprehensive Overview of Current Research
08/12/25 19:00 from sars-cov-2
The SARS-CoV-2 nonstructural protein 15 (Nsp15) is an endoribonuclease that plays a critical role in viral replication and immune evasion through its NendoU domain. The unique enzymatic mechanism of Nsp15 has attracted considerable atten...
» Predictive Markers of SARS-CoV-2 Spike-specific Cytotoxic T Cell Activity Following Omicron Breakthrough Infection
08/12/25 19:00 from sars-cov-2
At a population level, evaluation of vaccine efficacy and of immunity in general focuses on measuring humoral immunity, especially antibody-mediated neutralization. However, antibody-dependent cell-mediated cytotoxicity (ADCC) and cellul...
» In Silico Exploration of Potential Inhibitors Targeting SARS-CoV-2 Non-Structural Protein 15 (Nsp15): A Comprehensive Overview of Current Research
08/12/25 19:00 from coronavirus
The SARS-CoV-2 nonstructural protein 15 (Nsp15) is an endoribonuclease that plays a critical role in viral replication and immune evasion through its NendoU domain. The unique enzymatic mechanism of Nsp15 has attracted considerable atten...
» Work ability trajectories and sick leave in individuals with post COVID-19 condition: 3-year follow-up of a population-based cohort
08/12/25 19:00 from sars-cov-2
BACKGROUND: Data on the longer-term impact of post COVID-19 condition (PCC) on work-related functioning is limited, despite evidence on the persistence of PCC for years after infection. This study aimed to describe changes in work abilit...
» COVID-19 and Stroke: Evaluating Correlations, Risk Factors, and Patient Outcomes
08/12/25 19:00 from coronavirus
Coronavirus disease 2019 (COVID-19) has been associated with a range of neurological complications, including an increased risk of stroke. This study aimed to examine the relationship between COVID-19 and stroke risk in hospitalized pati...
» Distribution of D-Dimer and FDP Test Results among South Koreans: Reference Laboratory Data from 2017 through 2023
08/12/25 19:00 from sars-cov-2
CONCLUSIONS: D-dimer and FDP test results in South Koreans varied by age and gender. The COVID-19 pandemic significantly increased testing demand. These findings offer useful insights for diagnosing and treating thrombotic diseases.
» Distribution of D-Dimer and FDP Test Results among South Koreans: Reference Laboratory Data from 2017 through 2023
08/12/25 19:00 from coronavirus
CONCLUSIONS: D-dimer and FDP test results in South Koreans varied by age and gender. The COVID-19 pandemic significantly increased testing demand. These findings offer useful insights for diagnosing and treating thrombotic diseases.
» Clinical Usefulness of the Loop-Mediated Isothermal Amplification Assay for SARS-CoV-2 Detection
08/12/25 19:00 from sars-cov-2
CONCLUSIONS: The MmaxSure™ Fast SARS-CoV-2 Detection Kit, based on LAMP technology, exhibited a high level of diagnostic accuracy in detecting SARS-CoV-2. Its rapid turnaround time and minimal equipment requirements suggest its potential...
» Inside Out: The Influence of Identity, Context and Time on Faculty Motivation and Engagement
08/12/25 19:00 from sars-cov-2
CONCLUSION: Examining faculty engagement and motivation through SDT and practice theory with a longitudinal approach allowed us to understand how faculty perspectives about their roles as educators change over time and in relation to evo...
» Assessing the impact of COVID-19 pandemic on all-cause mortality and child mortality in a population cohort of Iganga Mayuge HDSS in Eastern Uganda (2015-2021)
08/12/25 19:00 from sars-cov-2
CONCLUSION: The COVID-19 pandemic increased all-cause mortality in the Iganga Mayuge HDSS population cohort in Eastern Uganda, particularly among children under five, likely due to restricted healthcare access and economic disruptions. P...