The FDA approved ensartinib for the treatment of certain patients with ALK-positive locally advanced or metastatic non-small cell lung cancer. The indication applies to use of the agent for adults not previously prescribed an ALK...
Individuals with pancreatic cancer underutilized palliative care and mental health services, according to a retrospective analysis. Researchers from Saint Louis University used electronic health record data from Optum’s Integrated...
Cancer Research UK concerned over dwindling participation in breast and cervical cancer screening A health charity has sounded the alarm over a dip in the proportion of people taking up the offer for cancer screening as figures show how...
A majority of patients expressed a desire to be notified when asked about the use of AI in health care, according to a research letter published in JAMA Network Open. Results like these regarding patient opinions “can support...
Tires and degrading garbage shed tiny pieces of plastic into the air, creating a form of air pollution that researchers suspect may be causing respiratory and other illnesses.
A centralized colorectal cancer screening intervention boosted fecal immunochemical test completion, as well as follow-up colonoscopy, among average-risk individuals served by federally qualified health centers, according to research....
SAN DIEGO — A treatment regimen of loncastuximab tesirine combined with venetoclax may be safe and effective in a subset of patients with non-Hodgkin lymphoma, according to early research presented at ASH Annual Meeting and Exposition....
New indication concerns treatment of adult patients with locally advanced, unresectable NSCLC whose tumours have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations
Researchers have revealed some of the precise mechanisms by which erroneous cells are recognized, marked for removal, and eliminated via apoptosis in developing zebrafish. Notably, they found that the protein Foxo3 may be a universal...
Healio spoke to the president of the American Academy of Dermatology after the organization issued a letter to the editor of The Atlantic with “serious concerns” over its article entitled “Against sunscreen absolutism.” Published on May...
Every cancer patient grapples with what is truly important. To bear witness to their attitude can put one’s own life in perspective Get our weekend culture and lifestyle email Tell me, what else should I have done? Doesn’t everything die...
Perioperative administration of 2% IV lidocaine had no significant effect on return of gut function at 72 hours among patients undergoing elective minimally invasive colonic resection, according to ALLEGRO trial results published in...
SAN ANTONIO — In this video, Raza Hoda, MD, discusses results from the DESTINY-Breast04 and DESTINY-Breast06 trials presented at San Antonio Breast Cancer Symposium. In this retrospective study, Hoda and colleague, Patrick McIntire, MD,...
SAN ANTONIO — In this video, Patrick McIntire, MD, discusses findings from the DESTINY-Breast04 and DESTINY-Breast06 trials presented at San Antonio Breast Cancer Symposium. The study assessed the rates of hormone receptor-positive,...
Medical researchers have announced the results of an innovative treatment approach that may offer improvement in overall survival in older patients with newly diagnosed glioblastoma while maintaining quality of life. Glioblastoma is the...
Researchers have discovered a process that breaks down mRNA molecules in the human body particularly efficiently. This could be useful, for example, in the treatment of cancer.
Craniopharyngiomas are brain tumors that negatively impact the hormonal function of the nearby pituitary. The tumor location often prevents necessary surgical intervention. Alternative pharmacological therapy requires an in-depth...
Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect our risk -- in opposite directions --...
Prostate cancer, especially in advanced stages such as castration-resistant prostate cancer, is challenging to treat. Traditional therapies targeting androgen receptor (AR) signaling have limited efficacy. In a recent study, researchers...
SAN ANTONIO — In this video, Judy Garber, MD, MPH, discusses the results of the OlympiA trial presented at San Antonio Breast Cancer Symposium. The study observed patients with BRCA1 or BRCA2 germline pathogenic variants and high-risk...
SAN ANTONIO — In this video, Shimoli Barot, MD, discusses the results of a study observing exceptional treatment response in patients with metastatic breast cancer presented at San Antonio Breast Cancer Symposium. The study observed the...
SAN DIEGO — Sustaining a successful mentor-mentee relationship requires compatibility in terms of skillsets and goals, according to a speaker at ASH Annual Meeting and Exposition. It also requires development of a career plan, as well as...
The FDA approved cosibelimab-ipdl for the treatment of certain patients with cutaneous squamous cell carcinoma. The indication applies to adults with metastatic or locally advanced disease who are not candidates for curative surgery or...
SAN ANTONIO — Weight loss via lifestyle intervention showed correlation to improved inflammatory markers in a group of women with HER2-negative breast cancer, according to a presenter here. Jennifer A. Ligibel, MD, professor of medicine...
Australia’s sun care guidelines differ depending on your skin tone – but most people are not adequately protecting themselves Australia has one of the highest rates of skin cancer in the world, but only two in five Australians use...
A study found multiple factors that contributed to invasive melanoma tumor upstaging as well as higher mortality rates among patients with upstaged tumors, one of which is medical management. According to a study conducted by Amanda...
SAN ANTONIO — Combining a poly(ADP-ribose) polymerase inhibitor with a PD-1 antibody in a nonchemotherapy regimen for BRCA-mutated breast cancer showed promise, according to a presenter here. Erica L. Mayer, MD, MPH, a medical oncologist...
An analysis of national data found that short-term mortality was not impacted for patients with advanced cancers during the shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023.
A new study offers new evidence that dietary changes may help reduce cancer cell growth in patients undergoing active surveillance, a treatment approach that involves regular monitoring of the cancer without immediate intervention. Men...
Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective....
Cancer immunotherapy has revolutionized treatment for patients, whereby the body's own immune system is harnessed to destroy cancer cells. Typically, several molecules restrain the ability of T cells to target cancer cells and developing...
Researchers have revealed the molecular structure of TRACeR-I, a protein platform for reprogramming immune responses. A better understanding of its structure may help optimize designs for the platform, which can be used to develop cancer...
A new screening method that combines laser analysis with a type of AI is the first of its kind to identify patients in the earliest stage of breast cancer, a study suggests.
Researchers are shining a light on cancer cells' energy centers -- literally -- to damage these power sources and trigger widespread cancer cell death. In a new study, scientists combined strategies to deliver energy-disrupting gene...
Analyses of self-tests for human papillomavirus (HPV) can be used to divide HPV-positive women into three risk groups, according to a new study. This method could be important for enhancing cervical cancer screening.
SAN ANTONIO — Elevated BMI increased risk for breast cancer mortality and distant recurrence among women with early-stage disease, according to findings presented at San Antonio Breast Cancer Symposium. Researchers observed this...
SAN ANTONIO — A randomized phase 3 clinical trial designed to assess whether circulating tumor DNA surveillance could be used to help prevent breast cancer recurrence closed early due to a lack of patients eligible for randomization....
Adults with low-risk thyroid cancer who underwent surgery had significant reductions in cancer-related fear and worry after their procedure compared with before surgery, researchers reported. For a study published in in The Journal of...
SAN ANTONIO — Surgical axillary staging as part of breast-conserving therapy may not be necessary for certain patients with early invasive breast cancer, according to findings presented at San Antonio Breast Cancer Symposium. Women with...
Researchers have discovered a protein variant that serves as a knob for regulating the body's innate immune response. The findings could lead to new therapies for Long COVID, autoimmune disorders, and more.
Researchers have successfully developed a deep learning model that classifies pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, into molecular subtypes using histopathology images. This approach achieves...
The first study comparing surgery to active monitoring as treatment for ductal carcinoma in situ (DCIS) finds women who carefully monitor the precancerous cells are no more likely to develop breast cancer after two years than women who...