USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: iron overload in the brain. Their study revealed that individuals with both conditions had twice the iron...
A new way of thinking about Alzheimer's disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer's and other neurodegenerative diseases, including ALS and Parkinson's.
While Alzheimer's disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body. Working with the laboratory fruit fly, researchers provide a new understanding...
In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The therapeutic molecules self-assemble into...
Learning about one's risk for Alzheimer's disease may not lead to emotional distress, but motivation to maintain healthy lifestyle changes tends to fade over time, even in people at high risk, according to a new study.
A new study examines the choices healthy research volunteers make when given the opportunity to learn their risk of developing Alzheimer's disease dementia. The researchers found a large discrepancy between the percentage of participants...
An increase in physical activity between the ages of 45 and 65 could help prevent Alzheimer's disease, while inactivity may be detrimental to brain health.
New research sheds light on an understudied area of science: iron levels in the blood and their relationship to cognitive performance in women transitioning into menopause. The findings are good news for women experiencing brain fog and...
A new study found that a gene recently recognized as a biomarker for Alzheimer's disease is actually a cause of it, due to its previously unknown secondary function that triggers a pathway that disrupts how cells in the brain turn genes...
Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the brain appears to play a major role by...
A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering human immune cells called microglia, the...
Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms. This is evident in the levels of the...
A research team has identified a previously unknown enzyme, SIRT2, that plays a key role in memory loss associated with Alzheimer's disease (AD). The study provides critical insights into how astrocytes contribute to cognitive decline by...
A preclinical study using cell cultures has found that some antibiotics may help address a genetic mutation associated with forms of early onset dementia.
Brain atrophy can refer to a loss of brain cells or a loss in the number of connections between these cells. In this article, learn about the symptoms of brain atrophy, as well as some causes and treatments.
A new study found a link between inadequate hydration and poorer cognitive functioning, especially in memory and attention tasks — but only in older women.
A new mouse study uses a two-pronged approach to designing a vaccine for dementia. The results are encouraging, and a clinical trial may be on the horizon.
In a mouse study, researchers have tested the potential of a ketone ester-rich diet in slowing down Alzheimer's, and have found this approach promising.
New research in mice and flies suggests that failure to transport molecules that break down proteins in neurons may lead to neurodegenerative diseases.
A 6-year study of 1,000 people aged 70–90 found no difference in rates of memory or cognition decline among participants who did or did not use statins.
There are many reasons a person’s leg could be shaking, from restless legs syndrome to anxiety. Read this article to learn about 10 possible causes of a shaky leg.
In a new review of the evidence, scientists propose two main types of Parkinson's, depending on which part of the nervous system the disease originates in.
Hackney-born actor Ray Winstone is challenging runners inspired by Virgin Money London Marathon 2018 to secure their place in next year’s event to help raise over £3.5m for dementia research.
A study published yesterday (11 April) suggests fluctuations in the female hormone oestrogen over a woman's life played a bigger role than age of menopause onset alone.
A nationwide study of 2.8 million people over 36 years in Denmark has found that a person’s risk of developing dementia increases with the number and severity of traumatic brain injuries.
A Vancouver-based research team led by Dr Patrick McGeer, has published a paper suggesting that anti-inflammatory drugs could prevent Alzheimer’s disease.