New research from Houston Methodist reveals how obesity may directly drive Alzheimer’s disease. Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can carry harmful signals that accelerate...
Researchers in Japan discovered that Parkinson’s patients diagnosed in their 80s are far more likely to show signs of amyloid buildup, a hallmark of Alzheimer’s, even without dementia symptoms. The study compared younger and older...
For decades, scientists believed Alzheimer’s was driven mainly by sticky protein plaques and tangles in the brain. Now Purdue researchers have revealed a hidden culprit: fat. They found that brain immune cells can become clogged with...
Chronic insomnia may do more than leave you groggy, it could speed up brain aging. A large Mayo Clinic study found that people with long-term sleep troubles were 40% more likely to develop dementia or cognitive impairment, with brain...
Scientists discovered that certain blood proteins linked to brain injury and inflammation strongly correlate with early signs of memory and cognitive decline, especially in Hispanic and Latino adults. This breakthrough points to a future...
Scientists at the University of Bath have developed a simple three-minute brainwave test called Fastball EEG that can detect memory problems years before Alzheimer’s is typically diagnosed. Unlike traditional memory tests, it passively...
A sweeping review of nearly 100 studies has raised concerns about the mental health impacts of high-potency cannabis products. Researchers found strong links to psychosis, schizophrenia, and cannabis use disorder, while results for...
Harvard scientists have uncovered that lithium, a naturally occurring element in the brain, may be the missing piece in understanding Alzheimer’s. Their decade-long research shows that lithium depletion—caused by amyloid plaques binding...
Using cannabis to self-medicate comes with hidden dangers—new research shows these users face higher paranoia and consume more THC. Childhood trauma further amplifies the risks, especially emotional abuse, which strongly predicts paranoia.
St. Jude researchers revealed that midkine blocks amyloid beta from forming harmful clumps linked to Alzheimer’s. Without it, the damaging assemblies accelerate, but with it, growth halts. The finding could inspire new drugs that harness...
THC levels in cannabis have soared in recent years, raising the risk of psychosis—especially in young, frequent users. Studies reveal a strong connection between cannabis-induced psychosis and schizophrenia, making early cessation and...
Scientists have discovered a direct cause-and-effect link between faulty mitochondria and the memory loss seen in neurodegenerative diseases. By creating a novel tool to boost mitochondrial activity in mouse models, researchers restored...
Many people with dementia endure long delays often over 3 years before receiving a diagnosis, with even longer waits for younger patients. A global review of over 30,000 cases reveals that age, dementia type, and systemic healthcare...
Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic amyloid beta plaques that cause Alzheimer’s. They identified a key receptor, ADGRG1, that enables this protective...
USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: iron overload in the brain. Their study revealed that individuals with both conditions had twice the iron...
A new way of thinking about Alzheimer's disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer's and other neurodegenerative diseases, including ALS and Parkinson's.
While Alzheimer's disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body. Working with the laboratory fruit fly, researchers provide a new understanding...
In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The therapeutic molecules self-assemble into...
Learning about one's risk for Alzheimer's disease may not lead to emotional distress, but motivation to maintain healthy lifestyle changes tends to fade over time, even in people at high risk, according to a new study.
A new study examines the choices healthy research volunteers make when given the opportunity to learn their risk of developing Alzheimer's disease dementia. The researchers found a large discrepancy between the percentage of participants...
An increase in physical activity between the ages of 45 and 65 could help prevent Alzheimer's disease, while inactivity may be detrimental to brain health.
New research sheds light on an understudied area of science: iron levels in the blood and their relationship to cognitive performance in women transitioning into menopause. The findings are good news for women experiencing brain fog and...
A new study found that a gene recently recognized as a biomarker for Alzheimer's disease is actually a cause of it, due to its previously unknown secondary function that triggers a pathway that disrupts how cells in the brain turn genes...
Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the brain appears to play a major role by...
A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering human immune cells called microglia, the...
Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms. This is evident in the levels of the...
A research team has identified a previously unknown enzyme, SIRT2, that plays a key role in memory loss associated with Alzheimer's disease (AD). The study provides critical insights into how astrocytes contribute to cognitive decline by...
A preclinical study using cell cultures has found that some antibiotics may help address a genetic mutation associated with forms of early onset dementia.
Brain atrophy can refer to a loss of brain cells or a loss in the number of connections between these cells. In this article, learn about the symptoms of brain atrophy, as well as some causes and treatments.
A new study found a link between inadequate hydration and poorer cognitive functioning, especially in memory and attention tasks — but only in older women.
A new mouse study uses a two-pronged approach to designing a vaccine for dementia. The results are encouraging, and a clinical trial may be on the horizon.
In a mouse study, researchers have tested the potential of a ketone ester-rich diet in slowing down Alzheimer's, and have found this approach promising.
New research in mice and flies suggests that failure to transport molecules that break down proteins in neurons may lead to neurodegenerative diseases.
A 6-year study of 1,000 people aged 70–90 found no difference in rates of memory or cognition decline among participants who did or did not use statins.