In a study, researchers use neuroimaging methods to examine brain resilience in regions of the brain linked to language and aging. They found that the hippocampus in bilinguals with Alzheimer's disease was noticeably larger than those...
New research has revealed a connection between ancient viral DNA embedded in the human genome and the genetic risk for two major diseases that affect the central nervous system.
New research quantified the association between loneliness and dementia by analyzing data from more than 600,000 people around the world. The meta-analysis of 21 longitudinal studies showed that experiencing feelings of loneliness...
Symptoms and disease progression of Rett syndrome are different in females than males. A new study shows why it is important to understand these differences to develop better treatments.
Neuroscientists have uncovered a mechanism that controls the reactivation of neural stem cells, which are crucial for repairing and regenerating brain cells. The research offers exciting potential for advancing our understanding and...
Researchers used mouse models and human post-mortem brain tissue to study the molecular underpinnings that may increase the risk of Alzheimer's after traumatic brain injury (TBI).
Alzheimer's disease may damage the brain in two distinct phases, based on new research using sophisticated brain mapping tools. According to researchers who discovered this new view, the first, early phase happens slowly and silently --...
Higher levels of HDL-C -- known as the 'good cholesterol' -- have been shown to correlate with heightened risk for Alzheimer's disease. A new study might explain why.
A new American Heart Association scientific statement suggests addressing cardiovascular health earlier in life may reduce the risk of stroke and help preserve thinking and memory later in life.
A new computer simulation of how our brains develop and grow neurons has been built. Along with improving our understanding of how the brain works, researchers hope that the models will contribute to neurodegenerative disease research...
A new study definitively reveals the existence of a system that had been theorized to clear metabolic wastes in the human brain. The study uses imaging in neurosurgery patients to show how brain's glymphatic system clears waste;...
Dementia doesn't just erode memory -- it also changes behavior and mental health. A study shows the brain's salience network and tau protein may be involved.
Researchers have identified individuals with increased risk for dementia using mobility data, recorded during a smartphone-based way-finding task on the university campus. The findings show the potential of smartphone data, collected in...
An international team of researchers have made a promising breakthrough in the development of drugs to treat Alzheimer's Disease. For the first time, scientists have developed a drug that works on both major aggregation-promoting...
Researchers show that a pill form of the drug dronabinol, an FDA-approved synthetic version of marijuana's main ingredient, THC, reduces agitation in patients with Alzheimer's by an average of 30%.
A research team systematically analyzed 40 empirical studies, the majority of which had found that outdoor air pollution is associated with differences in children's brains. These differences include volumes of white matter, which is...
Using a sophisticated brain-imaging system, neuroscientists say they have successfully reactivated a specific memory circuit in mice, causing them to seek out shelter when no shelter is actually present.
Investigators have found that two genetic variants that confer high risk of Alzheimer's disease (AD) together trigger a harmful inflammatory response in the brain's immune cells, particularly in females, in a preclinical model.
The most common cause of inherited prion diseases is the E200K mutation of the prion protein (PrP). It is often thought that this mutation causes disease by making PrP more susceptible to misfolding into a pathogenic shape (PrPSc)....
A study of nearly 2,000 former NFL players shows one-third believe that they have chronic traumatic encephalopathy (CTE). Those individuals were more likely to report cognitive symptoms, and 25% of them also reported suicidal thoughts....
A study more closely links obesity to dementia, finding that leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults.
A new study provides important insight into how amyloid-beta and tau proteins impact brain activity and possibly contribute to cognitive decline in Alzheimer's disease.
Two new papers by a team of researchers demonstrate that evaluating microRNAs in blood can be used not only to diagnose mild cognitive impairment (MCI) but also, critically, to predict the conversion from MCI to dementia due to...
Medical researchers conducted the largest-ever genome-wide association study of all-cause dementia, finding substantial genetic overlap with vascular dementia.
Researchers published a study showing that several measurements of the brain, including blood flow and the brain's ability to compensate for the lack of it, are better predictors of mild cognitive impairment than risk factors like...
Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.
Researchers have for the first time identified degeneration-associated 'molecular markers' -- observable changes in cells and their gene-regulating networks -- that are shared by several forms of dementia that affect different regions of...
A study found that new monoclonal antibody drugs for Alzheimer's may slow cognitive impairment through boosting levels of a specific protein in the brain.
Findings from a new study suggest that older people with mild cognitive impairment who engage in high levels of activities such as word games and hobbies have better memory, working memory, attention and processing speed than those who...
Findings from a new USC Dornsife study suggest that when older adults fall for financial scams, it could be an early warning sign of Alzheimer's disease. Researchers used MRI scans to find that older adults with thinner brain regions...
Research discovered a unique and promising avenue for diagnosing Alzheimer's disease (AD) earlier -- by analyzing AD biomarkers in blood -- so that the impacts of dementia can be reduced. The researchers applied inorganic analytical...
Researchers are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually...
Analysis of 1.6 million brain cells from older adults has captured the cellular changes that occur in Alzheimer's early stages, revealing potential new targets and routes for prevention.
Type 2 diabetes and prediabetes are associated with accelerated brain aging, according to a new study. The good news is that this may be counteracted by a healthy lifestyle.
Researchers assessed DNA methylation at 800,000 sites in the genome in blood samples collected from 900 people. The study includes extensive clinical information on participants, who all provided spinal fluid samples, which have been...