Combining testosterone-blocking drugs in patients with prostate cancer relapse prevents the spread of cancer better than treatment with a single drug, a multi-institution, Phase 3 clinical trial has found.
A 10-year follow up study of nearly 2,500 U.S. men who received prostate cancer treatment will help inform decision making in terms of treatments and side effects for a diverse population.
More than 65,000 men fall ill with prostate cancer each year in Germany. Twelve thousand of them develop a treatment-resistant form which eventually ends in death. Now, a team of researchers has developed an active substance that might...
Men who are overweight or obese at age 18 have a higher risk of 17 different cancers later in life. This has been shown in a study at the University of Gothenburg. The research also describes how the youth obesity epidemic is expected to...
Investigators have developed a new approach for treating invasive bladder cancer without the need for surgical removal of the bladder. Removing the bladder is currently a standard approach when cancer has invaded the muscle layer of the...
Using MRI as a screening test alongside PSA density allowed detection of cancers that would have been missed by the blood test alone, according to new research.
Patients with localized prostate cancer have a good chance of survival, but mortality rates among those with advanced, metastatic forms of the condition remain high. Until now, the precise mechanism behind the spread of the tumor has not...
Three new biomarkers for prostate cancer have been identified to help pinpoint potentially aggressive cases of the disease, which kills 300,000 men each year.
Prostate cancer is a leading cause of death among American men, and it's resistant to one of the most powerful chemotherapy medications -- cisplatin. Now, researchers have developed the first therapy of its kind that disrupts prostate...
The combination of two oral medications has shown positive results in people with prostate cancer, whose disease has spread to other parts of the body. Compared with XTANDI plus placebo, the investigatory combination of TALZENNA and...
New research shows that men who stick to a predominantly Mediterranean diet are less likely to be diagnosed with prostate cancer. This diet also improves their chances of recovery if they have PC and are undergoing radiation treatment.
Researchers have developed an ultra-soft and highly stretchable tissue-adhesive hydrogel-based multifunctional implantable sensor for monitoring of overactive bladder.
Bowel leakage, the need for anal incontinence protection and a restricted social life may cause severe, decades-long suffering among women with obstetric injuries to the anal opening, according to a new study.
Researchers have helped develop a new blood test to detect prostate cancer with greater accuracy than current methods. New research shows that the Prostate Screening EpiSwitch (PSE) blood test is 94 per cent accurate -- beating the...
Researchers discover a potential therapeutic avenue via neuronal endocrine receptors that could be helpful in battling an aggressive form of prostate cancer.
A single bout of exercise has been shown to elevate anti-cancer proteins called myokines in people with advanced prostate cancer, to levels which can significantly suppress tumour growth.
A family history of cancer and genetic variants that might be inherited appear to be important risk factors for Black men diagnosed with early-onset prostate cancer, a study has found.
Vaginal birth after a previous cesarean section is associated with an increased risk of pelvic floor surgery compared with planning another cesarean, according to a new study. The findings provide useful information to help women who...
A new technique which combines the use of two ultrasound technologies may offer an option to move kidney stones out of the ureter with minimal pain and no anesthesia, according to a new feasibility study.
An epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by activating the immune system, reports a new study in mice. The drug is now being tested in a national...
Researchers have identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer.
Researchers have made an important discovery about how prostate cancer may start to develop. A new study reveals that the prostate as a whole, including cells that appear normal, is different in men with prostate cancer. It suggests that...
Lower immunity and recurring infections are common in type 1 and type 2 diabetes. Researchers now show that the immune system of people with diabetes has lower levels of the antimicrobial peptide psoriasin, which compromises the urinary...
A large-scale study looked at the impact of incorporating genetic risk for cancer into the GP triage and referral processes in the UK. The research concluded that considering genetic risk could improve referrals for those in need -- and...
Men with early, curable stages of prostate cancer are missing opportunities to have their cancer detected because national guidelines and media health campaigns focus on urinary symptoms despite a lack of scientific evidence, say experts...
Male sex hormones interfere with the body's ability to fight bladder cancer, likely explaining why males experience higher cancer rates and more deadly disease, according to a new study.
Practice-changing research shows that a combination of androgen deprivation therapy -- a commonly used hormone injection -- plus pelvic lymph node radiation, kept nearly 90% of clinical trial patients' prostate cancer at bay for five years.
Over the past 15 years, public health authorities have downgraded recommendations for the prostate-specific antigen (PSA) test as a screening tool to reduce the overdiagnosis and overtreatment of men with low-grade prostate cancer. Now,...
Prostate cancers remain localized in the majority of cases, giving affected individuals a good chance of survival. However, about 20% of patients develop incurable metastatic prostate cancer, resulting in approximately 5,000 deaths each...
A new study finds that the incidence rate of metastatic prostate cancer has significantly increased for men 45 and older and coincides with recommendations against routine prostate cancer screenings.
Women with overactive bladder are frequently frustrated with treatment, which leads to discontinuation of therapy. Asynchronous telehealth visits keep women engaged in follow-up care, accelerates trials of different medications and...
Results from an international, randomized, double-blind, placebo-controlled, phase 3 clinical trial indicate that adding the androgen-receptor inhibitor darolutamide to androgen-deprivation therapy and chemotherapy prolongs the survival...
The combination of a novel blood test and magnetic resonance imaging (MRI) can reduce overdiagnosis of low-risk cancers as well as societal costs in prostate cancer screening, according to a cost-effectiveness study.
A new analysis has uncovered a potential link between higher prostate cancer risk and genetic variants associated with higher bloodstream levels of the cholesterol-transporting molecule lipoprotein A.
A molecular feature in prostate cancer, called endogenous retroviral (ERV) RNA, has been found to have prognostic value and also distinguish differences between men of African and European or Middle Eastern ancestry, according to a new...
If you're feeling more sudden urges to run to the bathroom as you age, you're not alone. A new study suggests postmenopausal women aged 45 to 54 years are more likely to have overactive bladder (OAB) syndrome. Additionally, obesity and...
Prostate cancer screening results differ in men taking cholesterol-lowering statin drugs compared with non-users, a study finds. In statin users, screening did not increase the incidence of prostate cancer as it did in other men.
Researchers have pioneered a new method to track the progression of prostate cancer in mice, from its birth to its spread into other tissues. This approach allows researchers to study the origins of prostate cancer in a more realistic...
Researchers have shown that a prostate cancer urine test can identify men at 'intermediate risk' who can safely avoid immediate treatment and benefit from 'active surveillance' instead. Previously, the team's Prostate Urine Risk (PUR)...
Researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. While more research will be necessary, the study's...
New research shows bed and rest might not be the best treatment for people suffering from cancer -- in fact, the opposite may be true. Researchers have discovered the proteins created by the body when exercising - called myokines -- can...
More than half of U.S. women will experience at least one urinary tract infection (UTI) in their lifetimes, while a quarter will have a subsequent infection. Recurrent urinary tract infections are defined as two or more infections in six...
Two recent studies describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors. Despite the differences between these cancers and their associated...
Researchers have established one of the world's largest collections of living tumors from prostate cancer patients, accelerating the testing of new treatments for prostate cancer and leading to faster patient benefit.
Researchers have unveiled important new insights into how hormones known as androgens act on our cells - and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.
Scientists have established organoid culture models from prostate tumor biopsies. These are small clusters of cells which can be used to test the efficacy of various drugs. In this way, it is possible to test which treatment will most...