Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key brain cells, restoring vital dopamine communication and neuroprotective signals in a mouse model of genetic...
A new study suggests that mindfulness training and/or non-invasive brain stimulation could reduce bladder leaks and feelings of urgency in patients with 'latchkey incontinence.'
Higher maternal selenium levels during pregnancy were associated with a lower risk of streptococcal infections in children, suggesting a potential protective effect.
Head and neck cancer researchers are reporting the development and testing of HPV-DeepSeek, a novel liquid biopsy assay. In their new study, HPV-DeepSeek achieved 99% sensitivty and specifity for diagnosing HPV-associated head and neck...
A newly published study indicates that prostate cancer can be diagnosed at an early stage through a simple urine sample. With the aid of AI and extensive analyses of gene activity in tumors, they have identified new biomarkers of high...
Researchers report an association between urinary incontinence and cardiovascular disease risk in women. The researcher recommend women should be checked regularly for urinary incontinence.
Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, Cilengitide, was found to reduce kidney...
Researchers have demonstrated how specific biomarkers in the blood can predict the development of dementia up to ten years before diagnosis, among older adults living independently in the community.
The reuse of human urine would allow for the production of sustainable fertilizers for urban agriculture, with significant environmental benefits, a new study concludes. The research evaluates the environmental impact of nitrogen...
High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice.
Eating behavior is associated with symptoms of pelvic floor disorders in middle-aged women. For example, higher consumption of highly processed ready-made foods and fast food increased the risk for experiencing symptoms of stress and...
Over 1,000 genes may serve as possible treatment targets for individuals with kidney disease, according to a new study. By creating the most complete and detailed genetic 'map' of kidney function to date, the researchers have paved the...
New insights into what causes the painful and disruptive symptoms of urinary tract infections (UTIs) could offer hope for improved treatment. UTIs are one of the most prevalent bacterial infections globally, with more than 400 million...
Men undergoing radiation therapy for prostate cancer who experience side effects early in treatment may face a higher risk of developing more serious long-term urinary and bowel health issues, according to a new study.
By studying biomarkers known to be involved in gastrointestinal cancers, researchers have developed a biomarker algorithm that, when combined with a noninvasive method to collect esophageal cells for study, could give clinicians insight...
Patients with a common aggressive type of bladder cancer could get correct treatment significantly quicker as new research suggests that initial MRI imaging and biopsy could be used to reduce the time patients wait.
Researchers discover novel targets for bladder cancer therapeutics and demonstrate that a new combination of existing drugs, including statins, blocks tumor growth in mice.
Researchers have identified six new biomarkers that could detect kidney injury faster and with more sensitivity, advancing safer drug development and improving health outcomes for patients. The new biomarkers may offer a more sensitive...
There are several strategies for the early detection of prostate cancer. The first step is often a blood test for prostate-specific antigen (PSA). If PSA levels exceed a certain threshold, the next step typically involves taking a tissue...
Researchers have found definitive proof of a kidney microbiome that influences renal health and kidney stone formation, demonstrating that the urinary tract is not sterile and low levels of bacteria are normal. The publication describes...
Scientists have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood. The finding could open the door to better ways to manage high blood...
The detection of cancer-associated micro-ribonucleic acids (miRNAs) in urine through a combination of nanowire-based miRNA extraction and machine learning (ML) analysis can fuel the development of early-stage cancer diagnostic tools.
Using computational tools, researchers have developed a method to assess which patients with metastatic triple-negative breast cancer could benefit from immunotherapy.
Researches made major strides toward the creation of artificial kidney tissue by demonstrating an undiscovered mechanism behind kidney development and a novel technique for culturing kidney cells, both of which could ultimately reduce...
A study has revealed a significant genetic risk factor for kidney disease in people from Ghana and Nigeria. Their study demonstrated that having just one risk variant in a gene known as APOL1 can significantly increase the risk of...
According to a study, the RNA (a type of genetic material) and other substances within urine can show changes in cell types, revealing early signs of cancer and other diseases. This method could help clinicians detect problems earlier...
It is just as safe and effective for people with HIV in need of kidney transplantation to get their organ from donors who are also HIV positive as it is from donors who are not infected with the virus, a study shows. Survival rates for...
How bladder cancer originates and progresses has been illuminated as never before. Researchers found that antiviral enzymes that mutate the DNA of normal and cancer cells are key promoters of early bladder cancer development, and that...
A new study has demonstrated a new, non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma, the most common form of kidney cancer.
A blood test that uses artificial intelligence (AI) to detect cancer-related genetic changes and protein biomarkers could help screen women for early signs of ovarian cancer, according to a new study.
A multi-institutional clinical trial showed that a newer technique for collecting prostate biopsy samples reduced the risk of infection compared with traditional biopsy approaches.
Researchers have developed a new method that could be a significant step in the treatment of chronic kidney disease. The method can predict the progression of the disease, which could ensure better and more targeted treatment and reduce...
Researchers have developed a prototype for a smart mask that can be used to monitor a range of medical conditions, including respiratory ailments, such as asthma, COPD (chronic obstructive pulmonary disease), and post-COVID-19 infections.
Detecting diseases early requires the rapid, continuous and convenient monitoring of vital biomarkers. Researchers have now developed a novel sensor that enables the continuous, and real-time detection of solid-state epidermal...
A physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.
A new study has found that routine lab tests may not be useful in making a long COVID diagnosis for people who have symptoms of the condition. The study highlights how challenging it can be to identify and diagnose a novel illness such...
Doctors recommend making fruits and vegetables a foundational part of the treatment of patients with hypertension. Diets high in fruits and vegetables are found to lower blood pressure, reduce cardiovascular risk, and improve kidney...
Development of a new way to accurately measure human serum albumin (HSA) levels in people with chronic kidney disease has progressed in recent testing.
A recent study examined data from more than 10,000 patients with 'Biopsy Gleason Grade Group (GGG) 1,' a diagnosis considered to be the lowest grade cancer. Researchers found that even among patients diagnosed using the most modern...
A loss of salt and body fluid can stimulate kidney regeneration and repair in mice, according to a new study. This innate regenerative response relies on a small population of kidney cells in a region known as the macula densa (MD),...
Transgender women are still at risk for prostate cancer. A new study concludes that current screening guidelines could miss early-stage prostate cancer in transgender women on hormone therapy.
The structure and function of the kidneys is altered by space flight, with galactic radiation causing permanent damage that would jeopardise any mission to Mars, according to a new study led by researchers from UCL.
Researchers have created a urine-based test that detects pieces of DNA fragments released by head and neck tumors. The test could potentially facilitate early detection of this cancer type, which currently does not have a reliable...
Scientists have successfully grown 'mini kidneys' in the lab and grafted them into live mice, revealing new insights into the metabolic defects and a potential therapy for polycystic kidney disease.
Type 2 diabetes is associated with increased risk of kidney stones, but some forms of treatment for this condition may also have the benefit of lowering risk of kidney stones. Researchers found that there was an association between the...