Researchers at the Icahn School of Medicine at Mount Sinai have developed a powerful computational tool, named iDOMO, to improve the prediction of drug synergy and accelerate the development of combination therapies for complex diseases.
Researchers have developed a powerful computational tool, named iDOMO, to improve the prediction of drug synergy and accelerate the development of combination therapies for complex diseases. The study highlights iDOMO's ability to...
Cancer cells work together to source nutrients from their environment-a cooperative process that was previously overlooked by scientists but may be a promising target for treating cancer.
Breast cancer incidence trends in U.S. women under 40 vary by geography and supports incorporating location information with established risk factors into risk prediction, improving the ability to identify groups of younger women at...
A new study led by researchers from Oxford Population Health has shown that a range of environmental factors, including lifestyle (smoking and physical activity), and living conditions, have a greater impact on health and premature death...
Despite similar availability of diagnostic technologies to women of different racial and ethnic groups, significant disparities were seen in who actually received same-day diagnostic services and biopsies after abnormal mammogram...
Different sociodemographic groups, especially racial and ethnic minorities, are less likely to receive timely breast cancer diagnostic services after an abnormal screening mammogram, according to a study published today in Radiology, a...
TV, radio and online adverts aimed at increasing uptake of routine mammograms for women aged 50 to 71 Women in England will be encouraged to attend potentially life-saving screenings for breast cancer in TV, radio and online adverts as...
Aging is a privilege, but it also brings risks -- including an increased likelihood of developing age-related diseases including cancer. Researchers have now created a landmark atlas of how healthy breast tissue ages, revealing key...
Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD Anderson Cancer Center have uncovered a biomarker capable of accurately predicting outcomes in meningioma brain...
Black women in the UK face a disproportionately higher risk of dying from breast cancer, often diagnosed at later stages with more aggressive forms of the disease.
Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long noncoding RNA (lncRNA) 'XIST' could be...
Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues.
A new study of breast cancer survivors has found this psychosocial challenge impacts almost every important domain of their lives -- the emotional, behavioral, cognitive, relational and professional. A larger number of domains was...
Liposuction and plastic surgery aren't often mentioned in the same breath as cancer. But they are the inspiration for a new approach to treating cancer that uses engineered fat cells to deprive tumors of nutrition. Researchers at UC San...
If successful, the scheme could speed up testing and reduce radiologists’ workload by around half The NHS is launching the world’s biggest trial of artificial intelligence to detect breast cancer, which could lead to faster diagnosis of...
A national study seeking more effective treatment for deadly metaplastic breast cancer has identified two inhibitor drugs with the potential to interrupt disease progression.
Study finds too few women are told chemotherapy can cause early menopause – or given the drug that can lessen that risk Get our breaking news email , free app or daily news podcast When Patsy Mullen was diagnosed with breast cancer, she...
A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests that doctors may need to rethink current screening guidelines for detecting brain...
The inherited mutated gene WNT9B, which functions normally in embryonic prostate development, increases risk of adult prostate cancer, according to a new study.
There were 55,033 diagnoses of prostate cancer in England in 2023 compared with 47,526 diagnoses of breast cancer Prostate cancer is now the most commonly diagnosed in England, surpassing breast cancer for two consecutive years,...
Research into the disease has never been more far-reaching, but there is little consensus as to what is causing the rocketing rates of diagnosis in young adults In 2022, around 16% of the 20 million people with cancer worldwide were...
Successful test in breast cancer patients: the active agent digoxin, a cardiac medication, dissolves clusters of circulating breast cancer cells in the blood, thus reducing the risk of metastases formation.
A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod. This combination showed promising...
Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late effects of these treatments include...
A clinical trial demonstrates the effectiveness of telephone-delivered acceptance and commitment therapy (ACT) in reducing fatigue's interference with functioning and improving the quality of life for survivors of metastatic breast...
Two new studies have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast cancer.
In patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared to trastuzumab...
Findings from a multi-institutional, international study have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player in hereditary cancer risk.
First real-world test finds approach has higher detection rate without having a higher rate of false positives The use of artificial intelligence in breast cancer screening increases the chance of the disease being detected, researchers...
Researchers have developed a non-invasive method to improve the effectiveness of chemotherapy while reducing its harmful side effects. By applying brief, localized pulses of magnetic fields, the team demonstrated a significant increase...
Tumor cells circulating in the blood are the 'germ cells' of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy resistance difficult. A team has now...
Patients diagnosed with late-stage or metastatic breast cancer have a statistically significant increased risk of pre-diagnosis cardiovascular disease (CVD) compared to those with early-stage cancer at diagnosis.
A new study explores whether cannabidiol (CBD), a component of marijuana, can reduce anxiety levels, specifically among patients with advanced breast cancer before a scan assessing tumor burden.
A new screening method that combines laser analysis with a type of AI is the first of its kind to identify patients in the earliest stage of breast cancer, a study suggests.
The first study comparing surgery to active monitoring as treatment for ductal carcinoma in situ (DCIS) finds women who carefully monitor the precancerous cells are no more likely to develop breast cancer after two years than women who...
The future of breast cancer screening and risk-reducing strategies is being shaped by artificial intelligence (AI), according to a recent review article.
Oral minoxidil is a commonly prescribed treatment for hair loss. The drug is also the active ingredient in over-the-counter Rogaine. The prescription treatment is known, however, to dilate blood vessels, and experts worry that this could...
Metastasis is responsible for 90 percent of cancer deaths. Researchers have found that the mutations driving it may stem from a commonly inherited variant of the PCSK9 gene.
Exposure to these toxic compounds, found in everyday items, could be elevating cancer risk in young women More than 400 chemicals regularly used in everyday plastic products are linked to breast cancer, and the dangerous compounds could...
An MRI-based imaging technique predicts the response of ovarian cancer tumors to treatment, and rapidly reveals how well treatment is working, in patient-derived cell models.
A groundbreaking phase one clinical trial explored a novel cell-based immunotherapy for breast cancer. The study focuses on a new treatment approach that aims to harness the body's immune system to enhance patient responses and reduce...
A new method of analyzing mammograms identified individuals at high risk of developing breast cancer more accurately than the standard, questionnaire-based method did. The new method, powered by artificial intelligence, could help...
Improvements in cancer prevention and screening have averted more deaths from five cancer types combined over the past 45 years than treatment advances, according to a modeling study. The study looked at deaths from breast, cervical,...
A new study has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted therapies.
Today, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low-risk tumors have a long-term benefit for at least 20 years, while the benefit was more short-term...