The tissue adjacent to a tumor behaves differently than areas farther away: The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven in which the tumor can grow....
A University of Massachusetts Amherst-Ernest Pharmaceuticals team of scientists has made "exciting," patient-friendly advances in developing a non-toxic bacterial therapy, BacID, to deliver cancer-fighting drugs directly into tumors.
Two new studies have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast cancer.
Today, the National Comprehensive Cancer Network (NCCN)-an alliance of leading cancer centers-published a new resource to inform people about the latest recommendations around hereditary and familial cancer risk.
Two new studies led by researchers at Washington University School of Medicine in St. Louis have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast...
Nearly a third of people in the U.S. have been exposed to unregulated contaminants in their drinking water that could impact their health, according to a new analysis by scientists at Silent Spring Institute.
In patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared to trastuzumab...
Many women worry hormonal contraceptives have dangerous side-effects including increased cancer risk. But this perception is often out of proportion with the actual risks.
An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture...
Scientists at Children's Medical Research Institute have solved a big mystery in cancer research – why cells die in different ways following radiotherapy.
Findings from a multi-institutional, international study have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player in hereditary cancer risk.
First real-world test finds approach has higher detection rate without having a higher rate of false positives The use of artificial intelligence in breast cancer screening increases the chance of the disease being detected, researchers...
Researchers have developed a non-invasive method to improve the effectiveness of chemotherapy while reducing its harmful side effects. By applying brief, localized pulses of magnetic fields, the team demonstrated a significant increase...
Tumor cells circulating in the blood are the 'germ cells' of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy resistance difficult. A team has now...
Patients diagnosed with late-stage or metastatic breast cancer have a statistically significant increased risk of pre-diagnosis cardiovascular disease (CVD) compared to those with early-stage cancer at diagnosis.
A new study explores whether cannabidiol (CBD), a component of marijuana, can reduce anxiety levels, specifically among patients with advanced breast cancer before a scan assessing tumor burden.
A new screening method that combines laser analysis with a type of AI is the first of its kind to identify patients in the earliest stage of breast cancer, a study suggests.
The first study comparing surgery to active monitoring as treatment for ductal carcinoma in situ (DCIS) finds women who carefully monitor the precancerous cells are no more likely to develop breast cancer after two years than women who...
The future of breast cancer screening and risk-reducing strategies is being shaped by artificial intelligence (AI), according to a recent review article.
Oral minoxidil is a commonly prescribed treatment for hair loss. The drug is also the active ingredient in over-the-counter Rogaine. The prescription treatment is known, however, to dilate blood vessels, and experts worry that this could...
Metastasis is responsible for 90 percent of cancer deaths. Researchers have found that the mutations driving it may stem from a commonly inherited variant of the PCSK9 gene.
Exposure to these toxic compounds, found in everyday items, could be elevating cancer risk in young women More than 400 chemicals regularly used in everyday plastic products are linked to breast cancer, and the dangerous compounds could...
An MRI-based imaging technique predicts the response of ovarian cancer tumors to treatment, and rapidly reveals how well treatment is working, in patient-derived cell models.
A groundbreaking phase one clinical trial explored a novel cell-based immunotherapy for breast cancer. The study focuses on a new treatment approach that aims to harness the body's immune system to enhance patient responses and reduce...
A new method of analyzing mammograms identified individuals at high risk of developing breast cancer more accurately than the standard, questionnaire-based method did. The new method, powered by artificial intelligence, could help...
Improvements in cancer prevention and screening have averted more deaths from five cancer types combined over the past 45 years than treatment advances, according to a modeling study. The study looked at deaths from breast, cervical,...
A new study has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted therapies.
Today, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low-risk tumors have a long-term benefit for at least 20 years, while the benefit was more short-term...
Health Services Safety Investigation Body reveals difficulties inmates have when they leave jail for treatment A female inmate remained handcuffed to a male prison officer while she had a mammogram, in an example of prisoners being...
Tamoxifen is a common and important treatment to prevent breast cancer from recurring. A new study shows that variation in a patient's gut microbiome can impact how effective the treatment is.
A new study finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic...
Researchers have pinpointed what could be the early genetic origins of breast cancer -- cancer-like mutations appearing in the cells of healthy women. In a new study, the international collaborators analyzed the genomes of more than...
National Institute for Health and Care Excellence unable to reach price agreement with manufacturers of Enhertu A breast cancer charity has said it was “beyond devastated” that talks to make a life-extending drug available on the NHS to...
Jailed breast surgeon gives evidence for first time at inquest into deaths of 62 of his former patients The jailed breast surgeon Ian Paterson has said he did not tell women if he was going to perform an unauthorised cleavage-sparing...
A new analysis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -- and the cells of a tumor's surrounding environment -- are organized, in 3D, and how...
Using computational tools, researchers have developed a method to assess which patients with metastatic triple-negative breast cancer could benefit from immunotherapy.
Research shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes subsequent activity in tumor suppression.
Researchers evaluated tissues for fibrosis using MeCo Score, a diagnostic tool that can potentially predict the likelihood of relapse or recurrence among patients with early-stage breast cancer.
Procedures performed by convicted breast surgeon were not a recognised or authorised type of operation The convicted breast surgeon Ian Paterson pitched one of his patients an unauthorised cleavage-sparing mastectomy “almost like a sales...
Researchers have developed an in vitro cancer model to investigate why breast cancer spreads to bone. Their findings hold promise for advancing the development of preclinical tools to predict breast cancer bone metastasis.
Midlife is relentless at tuning your body to a register of pain and mortality. When I think about the treatment my friend will go through, I am scared and filled with hope Every few months, one of my former college roommates sends a...
A new study has found some cancers to be slightly more frequent in people with multiple sclerosis (MS) than in people without MS. Types of cancers found to have a small increased risk include bladder, brain and cervical cancers. The...
Triple negative breast cancer (TNBC) remains the most aggressive and deadly type of breast cancer, but new findings from cancer researchers are pointing the way toward therapeutic strategies that could be tested in clinical trials in the...
Markers of cellular aging -- such as DNA damage response, cellular senescence, and inflammatory pathways -- significantly increased in all breast cancer survivors, regardless of the type of treatment received.
Trial forms part of government plans to expedite referrals for patients with cancer symptoms Women who are concerned about lumps in their breasts will be able to book an appointment to see a specialist via the NHS app, without seeing a...
Report shows significantly improved survival rates but a steep increase in diagnoses among women younger than 50 A new report from the American Cancer Society (ACS) finds that breast cancer deaths have dropped dramatically since 1989,...