AI models analyzing tumor-infiltrating lymphocytes show promise in predicting outcomes for triple-negative breast cancer, but external validation reveals critical performance gaps.
Researchers at the University of British Columbia (UBC), BC Cancer, Harvard Medical School and Memorial Sloan Kettering Cancer Center (MSK) have pinpointed what could be the early genetic origins of breast cancer-;cancer-like mutations...
A spoonful of sugar might actually help the medicine go down, according to recent research from the University of Mississippi. And it could reduce the harmful side effects of cancer treatment.
A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast...
A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.
Researchers find bread consumption is not linked to cancer risk, with whole-grain bread potentially reducing colorectal cancer and total cancer mortality.
A new study finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic...
Researchers have pinpointed what could be the early genetic origins of breast cancer -- cancer-like mutations appearing in the cells of healthy women. In a new study, the international collaborators analyzed the genomes of more than...
Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic...
National Institute for Health and Care Excellence unable to reach price agreement with manufacturers of Enhertu A breast cancer charity has said it was “beyond devastated” that talks to make a life-extending drug available on the NHS to...
One-third of HER2-positive (HER2+) tumors express the P95HER2 protein, which associates with an aggressive form of breast cancer with a poorer prognosis. Investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Growth Factors...
Researchers at Karolinska Institutet in Sweden have investigated how well different AI models can predict the prognosis of triple-negative breast cancer by analyzing certain immune cells inside the tumor.
A commonly prescribed medication for heart failure was linked to a lower risk of heart damage, or cardiotoxicity, among high-risk cancer patients undergoing chemotherapy treatment using anthracyclines, according to preliminary...
Jailed breast surgeon gives evidence for first time at inquest into deaths of 62 of his former patients The jailed breast surgeon Ian Paterson has said he did not tell women if he was going to perform an unauthorised cleavage-sparing...
A new analysis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -- and the cells of a tumor's surrounding environment -- are organized, in 3D, and how...
Using computational tools, researchers have developed a method to assess which patients with metastatic triple-negative breast cancer could benefit from immunotherapy.
Research shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes subsequent activity in tumor suppression.
Researchers evaluated tissues for fibrosis using MeCo Score, a diagnostic tool that can potentially predict the likelihood of relapse or recurrence among patients with early-stage breast cancer.
Procedures performed by convicted breast surgeon were not a recognised or authorised type of operation The convicted breast surgeon Ian Paterson pitched one of his patients an unauthorised cleavage-sparing mastectomy “almost like a sales...
Researchers have developed an in vitro cancer model to investigate why breast cancer spreads to bone. Their findings hold promise for advancing the development of preclinical tools to predict breast cancer bone metastasis.
Midlife is relentless at tuning your body to a register of pain and mortality. When I think about the treatment my friend will go through, I am scared and filled with hope Every few months, one of my former college roommates sends a...
A new study has found some cancers to be slightly more frequent in people with multiple sclerosis (MS) than in people without MS. Types of cancers found to have a small increased risk include bladder, brain and cervical cancers. The...
Triple negative breast cancer (TNBC) remains the most aggressive and deadly type of breast cancer, but new findings from cancer researchers are pointing the way toward therapeutic strategies that could be tested in clinical trials in the...
Markers of cellular aging -- such as DNA damage response, cellular senescence, and inflammatory pathways -- significantly increased in all breast cancer survivors, regardless of the type of treatment received.
Trial forms part of government plans to expedite referrals for patients with cancer symptoms Women who are concerned about lumps in their breasts will be able to book an appointment to see a specialist via the NHS app, without seeing a...
Report shows significantly improved survival rates but a steep increase in diagnoses among women younger than 50 A new report from the American Cancer Society (ACS) finds that breast cancer deaths have dropped dramatically since 1989,...
From attending her own Dawn French-hosted funeral to saving women’s lives, the inspirational cancer campaigner’s incredible life is movingly captured in this documentary A terminal cancer diagnosis isn’t usually something that makes...
Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous...
Women worldwide could see better treatment with new AI technology which enables better detection of damaged cells and more precisely predict the risk of getting breast cancer, shows new research.
Cancer incidence trends in 2021 largely returned to what they were before the COVID-19 pandemic, according to a study by researchers at the National Institutes of Health (NIH). However, there was little evidence of a rebound in incidence...
Non-smokers found to have 1% chance of treatment leading to disease compared with between 2% and 6% for smokers Breast cancer patients who continue to smoke after having radiotherapy are at much higher risk of their treatment causing...
Loss of key data when changing registered gender with GP means thousands are not invited to routine exams Thousands of transgender patients in England are missing out on vital cancer screening because of the way their GP records are...
New research identifies specific genetic changes that can increase a person's risk of breast and ovarian cancers, to help guide clinical decision-making.
According to a new 10-year study, screening for breast cancer with digital breast tomosynthesis (DBT) increases cancer detection rates and significantly reduces the rate of advanced cancers compared to conventional 2D digital mammography.
A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. The...
Researchers have discovered new insights into tumor-induced B cell changes in blood and bone marrow of triple negative breast cancer patients. The findings show two distinct patterns of B cell abnormalities that could serve as blood...
By now you would have seen the countless stories about supermodel Elle Macpherson and her breast cancer treatment choices. Most of the headlines and articles amplified her decision to forgo some standard medical treatments in favour of...
How many are now second-guessing their own treatment after the model’s dangerous intervention? Elle Macpherson believes, for some reason, that disease thrives in an acidic body . The Australian ex-supermodel swears by the benefits of...
I’m lucky I can text my biological father. Good donors must be available to the children they make, for their whole lives I’m what you might call a health nerd. Every week I do weights, I swim, I walk. My energy levels are great. I sleep...
Many media reports based on the supermodel’s interview with the Australian Women’s Weekly lack detail about the cancer and risk misinforming people A leading breast cancer surgeon claims many media reports that the supermodel Elle...
In a study using human breast cancer cells, scientists say they have potentially identified immune system white blood cells that appear to be the closest neighbors of breast cancer cells that are likely to spread. The researchers say the...
Supermodel says she is in remission after being diagnosed seven years ago and rejecting some aspects of conventional medicine Elle Macpherson has said she was diagnosed with breast cancer seven years ago but is now in remission despite...
A false-positive mammogram may deter women from future screenings, according to a new study. But staying on schedule remains key to early detection of cancer.
After a few dates, Marg Arnold was charmed by the new man in her life. When she discovered they both owned the same ‘sexy tool’, she knew they had a future together Find more stories from The moment I knew series here I’d been single for...
Having a mastectomy is tough enough without the added pressure to have a breast reconstruction just to conform to conventional representations of womanliness As a small-breasted woman, my boobs have rarely been ogled. Yet this year I’ve...
Women diagnosed with breast cancer who had regular screening mammograms every year were less likely to have late-stage cancer and had higher overall survival than those who received screening every other year or less often, according to...