An FDA advisory committee gives the nod to a sublingual opioid, but amid loud criticism around safety, while narrowly recommending against approval for an intravenous preparation. Medscape Medical News
(MedPage Today) -- This week's topics include undiagnosed diseases, sexual assault and mental and physical health in women, timing of TDAP in pregnancy, and statins beyond cardiovascular disease.
As the US opioid epidemic continues to grow, the need to find safe, effective, nonaddictive, nonopioid strategies for managing pain is increasingly urgent, say experts. Medscape Medical News
Patients who undergo heart valve surgery are at a heightened risk of cognitive decline in the first few months after surgery, suggests a paper published yesterday in the Journal of the American Geriatrics Association . “Aortic valve...
A higher-quality diet and lower body mass index have been linked to improved outcomes in patients with bipolar disorder, new research suggests. Medscape Medical News
Stress is a biological response to demanding situations and a regular part of daily life. Stress becomes chronic when the body’s response goes on for a prolonged period. Chronic stress can have a range of health effects. Learn more about...
A new study suggests that dementia risk is increased and accelerated in seniors with atrial fibrillation, but treatment of AF with oral anticoagulants may reduce that risk. Medscape Medical News
The composition of gut microbiota is altered in patients with Alzheimer's disease, potentially supporting the inflammatory theory of the disease's pathogenesis, new research suggests. Medscape Medical News
Providing patients with a computer-based, shared decision-making tool may promote ongoing treatment engagement and adherence to antipsychotic medication regimens, according to a study in Psychiatric Services in Advance . Shared decision...
Childhood trauma, particularly sexual abuse, is more common in those with anxious depression and causes permanent biological changes, new research suggests. Medscape Medical News
Gamma-hydroxybutyrate, which is widely used as a 'party drug,' causes functional brain changes, especially after drug-related comas, Dutch researchers have shown for the first time. Medscape Medical News
Pregnant women with a history of depression and bipolar disorder are impaired in their ability to recognize baby facial expressions and cries, even if their condition is in remission, new research shows. Medscape Medical News
Individuals diagnosed with schizophrenia differ greatly from one another. Researchers have demonstrated that very few identical brain differences are shared amongst different patients. Therefore, insights based on research at the group...
Innovative approaches and widespread data sharing are essential to develop novel therapies that deliver on the long-held promise of precision medicine in psychiatry, says a European expert. Medscape Medical News
Youth and young adults with internalizing problems such as depression and anxiety and externalizing problems such as attention-deficit/hyperactivity disorder may be more likely to begin using tobacco products than those without these...
Researchers tracking the development of the brain's emotion circuitry in infancy found that adult-like functional brain connections for emotional regulation emerge during the first year of life. And the growth of these brain circuits...
Asking patients about their history with sexual harassment and abuse should be a routine part of psychiatric care, said APA Past President Nada Stotland, M.D., during her presentation at this year’s IPS: The Mental Health Services...
Can diet impact the effectiveness of treatment for bipolar disorder, particularly in the case of depressive episodes? A new study addresses this question.
Predicting who will develop dementia is difficult. Researchers are testing various biomarkers, but a recent study asks whether apathy might provide a clue.
A pilot study has found that pregnant women who have suffered from depression or bipolar disorder (i.e. both mania and depression) recognize babies' faces and how babies laugh or cry, differently to healthy controls. This happens even if...
Data from a clinical trial has shown that how people respond to treatment for Bipolar Disorder may be influenced by their weight and the overall quality of their diet, including whether they are eating a diet high in foods thought to...
More African Americans with schizophrenia who are not prescribed the antipsychotic clozapine because of low white blood cell counts could potentially use the drug safely, according to Deanna Kelly, Pharm.D., and Gopal Vyas, D.O. Kelly is...
A bipartisan legislative package passed yesterday by Congress takes many important steps toward combating the opioid crisis with a broad range of opioid treatment and prevention programs, said APA in a statement . “Opioid use disorder...
A 1 percent increase in statewide depression diagnoses was associated with a 26 percent increase in opioid-related deaths. Rates of opioid-related deaths rose substantially in 2014 and 2015, and states with the highest rates of...
Quantitative electroencephalography (QEEG) does not appear to be a reliable tool to predict how a person with major depression will respond to treatment, according to a meta-analysis published today in AJP in Advance . QEEG...
Brain imaging combined with baseline data about social functioning—such as how well one performs in school, at work, or in relationships—successfully predicted how well patients at high risk of psychosis and patients with recent-onset...
New research shows that a person's sense of agency and volition are not located in isolated brain regions, but in networks spread throughout the brain.
Studies show that a relatively small proportion of the population accounts for most health spending in the United States. By some estimates, 25% of Medicare beneficiaries account for 85% of Medicare costs. A study in Psychiatric Services...
Brain fog is a less well-known symptom of rheumatoid arthritis (RA). People with RA may have difficulty concentrating, or they may have memory problems. Learn about the link between RA and brain fog here.