In a bold step toward sustainable space travel, scientists are engineering a radically small, protein-rich rice that can grow in space. The Moon-Rice project, led by the Italian Space Agency in collaboration with three universities, aims...
Colossal Bioscience is adding the extinct animal to its revival wishlist, joining the woolly mammoth, dodo and thylacine. But scepticism is growing Standing more than three metres (10ft) high, the giant moa is the tallest bird known to...
Researchers from the University of Maryland's Department of Nutrition and Food Science are shedding new light on how a dangerous food-borne pathogen—Cronobacter sakazakii—may have adapted to thrive in dried and powdered foods across the...
Our genes underlie all aspects of life, from our looks to how our cells behave. This includes diseases, as genetic changes can underlie the development and progression of certain health problems. This is true for arteriovenous...
In a newly published article in Nature Genetics, researchers from the University of Chicago have identified tumor aneuploidy—an imbalance in the number of chromosomes—as a powerful biomarker associated with resistance to immunotherapy...
Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the formation of a malignant tumor.
It's been recognized for some time that Alzheimer's disease affects brain regions differently and that tau—a protein known to misbehave—plays an important role in the disease. Normally, tau helps stabilize neurons, but in Alzheimer's...
A new study by University of Michigan Rogel Cancer Center researchers identifies a cellular signature that explains why about one-third of prostate cancers respond especially poorly to treatment.
Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan report a way for the body to make its own weight-loss drugs, doing away with injections in favor of a one-time...
Researchers at Princeton University and the Simons Foundation have identified four clinically and biologically distinct subtypes of autism, marking a transformative step in understanding the condition's genetic underpinnings and...
Scientists at MIT have turbocharged one of nature’s most sluggish but essential enzymes—rubisco—by applying a cutting-edge evolution technique in living cells. Normally prone to wasteful reactions with oxygen, this revamped bacterial...
A research team led by Prof. Gu Hongcang and Zhang Fan from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has identified a novel long non-coding RNA (lncRNA)-driven regulatory network that plays a central...
The human brain is made up of billions of nerve cells (neurons) that communicate with each other in vast, interconnected networks. For the brain to function reliably, there must be a fine balance between two types of signals: Excitatory...
High heat and heavy metals dampen a bumblebee’s trademark buzz, threatening pollen release and colony chatter. Tiny sensors captured up-to-400-hertz tremors that falter under environmental stress, raising alarms for ecosystems and...
Researchers at the University of Tartu Institute of Genomics have gained a deeper understanding of why some people are more prone to experiencing side effects when taking antidepressants.
How much an infant cries is largely steered by their genetics, and there is probably not much that parents can do about it. This has been shown in a new Swedish twin study from Uppsala University and Karolinska Institutet in which...
Scientists at the Jules Stein Eye Institute at the David Geffen School of Medicine at UCLA have discovered that certain retinal cells can rewire themselves when vision begins to deteriorate in retinitis pigmentosa, a genetic eye disease...
New research has found a novel target with therapeutic potential for metastatic eye melanoma—an aggressive eye cancer—with implications for a range of other cancers.
Scientists have decoded the sea spider’s genome for the first time, revealing how its strangely shaped body—with organs in its legs and barely any abdomen—may be tied to a missing gene. The detailed DNA map shows this ancient creature...
Scientists have discovered that starving and then refeeding worms can reveal surprising secrets about aging. When a specific gene (called TFEB) is missing, these worms don’t bounce back from fasting—they instead enter a state that looks...
Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found.
Local clinics and technology could drive improvement if reorganisation doesn’t slow things down The NHS is a totemic institution in Labour’s history and that of the country, and voters care more about it than most things the government...
An EHU study analyzing different genetic markers associated with facial features of the European population has shown a strong link between 10 of these markers and the facial morphology of people from the Iberian Peninsula. The...
Nutrition scientists have been working to understand the relationship between type 2 diabetes and genes that express a salivary enzyme that breaks down starch, but many conflicting studies have led to few clear answers.
Alzheimer's disease (AD) is a common, debilitating neurodegenerative disease affecting about 10% of people over the age of 65 and one third of people aged 85 and above. Besides environmental factors, the genes have a strong influence on...
From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's typically efficient DNA repair machinery and potentially affecting our health and well-being.
New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates. This insight...
Scientists at UC Davis discovered a small genetic difference that could explain why humans are more prone to certain cancers than our primate cousins. The change affects a protein used by immune cells to kill tumors—except in humans,...
Researchers at McMaster University, Cleveland Clinic and Case Comprehensive Cancer Center have uncovered how a protein long associated with Alzheimer's disease helps lung cancer spread to the brain—a discovery that offers hope that...
Ancient DNA has revealed a genetic link between the cultures of ancient Egypt and Mesopotamia, according to research published Wednesday in the journal Nature.
A new study reveals that air pollution, traditional herbal medicines and other environmental exposures are linked to genetic mutations that may contribute to the development of lung cancer in people with no or hardly any history of smoking.
Unusual burial of man, thought to have been a potter, in sealed vessel may have helped DNA survive past four millennia A man whose bones were shaped by a lifetime of hard labour more than 4,500 years ago has become the first ancient...
Gene therapy can improve hearing in children and adults with congenital deafness or severe hearing impairment, a new study involving researchers at Karolinska Institutet reports. Hearing improved in all 10 patients, and the treatment was...
New cutting-edge software developed in Melbourne can help uncover how the most common heart tumor in children forms and changes. And the technology has the potential to further our understanding of other childhood diseases, according to...
By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an integrated gene signature for ferroptosis. They evaluated the associated genes in both mice and human liver injury...
Melanin can either protect or worsen hereditary hearing loss depending on genetic context, as reported by researchers from Japan. Using genetically engineered mice lacking the SLC26A4 gene, the researchers found that problems with...
Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.
Five-year SynHG project aims to pave way for next generation of medical therapies and treatment of diseases Researchers are embarking on an ambitious project to construct human genetic material from scratch to learn more about how DNA...
It has been 25 years since Bill Clinton announced one of humanity’s most important scientific achievements: the first draft of the human genome. At the time, there was a great deal of excitement about the benefits that this new knowledge...
Leafcutter ants live in highly organized colonies where every ant has a job, and now researchers can flip those jobs like a switch. By manipulating just two neuropeptides, scientists can turn defenders into nurses or gardeners into leaf...
Two Ice Age wolf pups once thought to be early dogs have been identified as wild wolves, thanks to detailed DNA and chemical analysis. Surprisingly, their last meals included woolly rhinoceros meat—an unusually large prey item—hinting...
In a remarkable twist of science, researchers have transformed a fungus long associated with death into a potential weapon against cancer. Found in tombs like that of King Tut, Aspergillus flavus was once feared for its deadly spores....
Newborns will have whole genome sequencing to enable personalised healthcare that predicts and prevents illness Every baby in England is to have a DNA screening to avoid fatal diseases and receive personalised healthcare as part of the...
My friend and former colleague David Hopkinson, who has died aged 89, was director of the Medical Research Council’s human biochemical genetics unit at University College London from 1976 until its closure in 2000. Hoppy, as he was...
Even after 20 million years of evolutionary separation, two tiny worm species show astonishingly similar patterns in how they turn genes on and off. Scientists mapped every cell s activity during development and found that genes...
During Earth's ancient Snowball periods, when the entire planet was wrapped in ice, life may have endured in tiny meltwater ponds on the surface of equatorial glaciers. MIT researchers discovered that these watery refuges could have...
New research is shaking up our understanding of evolution by revealing that some species may not evolve gradually at all. Instead, scientists discovered that certain marine worms experienced an explosive genetic makeover when they...
Information stolen from US company included details of 150,000 British residents including family trees The genetic testing company 23andMe has been fined more than £2.3m for failing to protect the personal information of more than...