Scientists discovered that aging cells can use malfunctioning mitochondria to unlock inflammatory genes and keep the immune system stuck in a prolonged state of alert. Blocking one part of this process reduced inflammation and improved...
Scientists have uncovered a natural braking system that helps the immune system switch off inflammation and prevent harmful immune cells from building up. Boosting this pathway in people reduced inflammation-related immune changes and...
Researchers found that blocking IL1RAP could disrupt a powerful inflammatory network that helps pancreatic cancer survive treatment. In preclinical experiments, the approach reduced tumor-protecting cells and fibrosis while boosting the...
Influenza remains a major global health challenge as continual antigenic drift can limit the breadth and durability of vaccine-induced antibody responses, requiring frequent vaccine updates.
Dengue virus is one of the most widespread vector-borne viral pathogens in the world. Nearly 400 million dengue virus infections occur each year, resulting in approximately 20,000 deaths.
Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most people recognize this progress in breakthroughs like immunotherapy-a treatment strategy first deployed in 2011 that leverages the body's own...
UCLA researchers developed ready-made cancer-fighting T cells from cord blood stem cells that can attack solid tumors through two separate detection systems. In mice, a single dose controlled cancer and extended survival while avoiding a...
The strain of Mpox behind the 2022 outbreak was a weakened form of the virus, which may have helped to spread it faster, a new study from the University of Surrey reports.
In an Arthritis & Rheumatology analysis of data on 60,980 US adults with autoimmune rheumatic conditions who developed COVID-19 between December 2020 and August 2024, those who received booster or updated (2023-2024) COVID-19 vaccines...
A research team comprising Associate Professor FUNAKOSHI Yohei, Associate Professor YAKUSHIJIN Kimikazu, Professor MINAMI Hironobu, and Associate Professor OHJI Goh of Kobe University, together with graduate student MASUDA Genki,...
New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) shows that people who have had COVID-19 have a lower, rather than higher, risk of...
The risk of being hospitalized for flu or pneumonia can be reduced with a high-dose flu vaccine for older people with chronic lung disease, according to the combined results of two large clinical trials presented at the European...
Scientists have found evidence that vulnerability to rheumatoid arthritis may begin before birth. Finger joints commonly affected by the disease develop with different tissue structures and larger populations of specialized fibroblasts...
The Gerontological Society of America (GSA) supports the 2026-27 respiratory season vaccine evidence review released on September 2, 2026, by the Vaccine Integrity Project (VIP) in collaboration with the American Medical Association.
Aging may be partly fueled by immune cells losing their ability to clear away damaged, inflammation-promoting cells. Blocking a single receptor restored that cleanup process in mice, reducing inflammation and helping their organs,...
Following nearly 10,000 older women for 10 years, researchers found that tea drinking was associated with slightly higher hip bone density. Moderate coffee consumption did not appear harmful, but drinking more than five cups a day was...
CAR T-cell therapy dramatically reduced disease activity in six people with severe rheumatoid arthritis that had resisted other treatments, with three achieving medication-free remission. The treatment may work by clearing out harmful...
Older adults who received the Shingrix shingles vaccine were 24% less likely to be diagnosed with dementia over four years in a study of more than 500,000 people. Researchers estimate the difference could amount to roughly one dementia...
Researchers have found a way to supercharge natural killer cells, powerful immune cells that can attack cancer, so they can penetrate solid tumors and keep fighting once inside. In mice, these specially prepared tissue-resident cells...
People who reach 110 and beyond appear to have unusually large numbers of rare immune cells capable of killing abnormal cells. These CD4 cytotoxic T cells became more common with age and often expanded into large groups of nearly...
Backyard bird feeders could become unexpected hotspots for H5N1 as Australia’s bird flu outbreak spreads, bringing species together in ways that rarely occur naturally. Experts say stopping feeding is safest, while smaller amounts of...
A hormone already known for curbing appetite and supporting weight loss may have a surprising second job: protecting the liver from inflammation and scarring. Researchers at McMaster University found that GDF15 activates a previously...
AI may be able to predict how strongly someone will respond to a vaccine before they receive it. By analyzing antibody patterns in more than 4,000 people, researchers found signs of “immune readiness” that helped distinguish strong...
A compound made when gut bacteria break down dietary fiber may do more than briefly calm inflammation—it could leave a lasting protective “memory” in the gut. Northwestern Medicine researchers found that butyrate can reprogram intestinal...
More than 1,000 genetic switches behave differently in male and female immune cells, helping explain why women are much more vulnerable to autoimmune diseases such as lupus. Female immune systems appear genetically tuned for stronger...
Orange juice may have a much bigger effect on the body than scientists once realized. Drinking it regularly appears to influence genes tied to inflammation, blood pressure, metabolism, and blood sugar control, while studies have also...
A specially engineered chewing gum reduced HPV by up to 93% and nearly eliminated two bacteria linked to head and neck cancer. The treatment preserved beneficial mouth bacteria, raising hopes for a safer and more affordable therapy.
A single 30-minute sauna session may briefly put the immune system on higher alert. Finnish researchers found that sauna heat, paired with a short cold shower, increased every type of white blood cell circulating in the bloodstream,...
A plant-derived compound reduced swelling, inflammation, and joint damage in rats with rheumatoid arthritis. It also helped rebalance immune activity and improve the way certain fats were processed in the body. Researchers say the...
For most adults, a daily caffeine habit may be safer for the heart than many people assume. A new American Heart Association review found that up to 400 milligrams of caffeine a day, roughly three to five cups of regular black coffee, is...
Scientists uncovered how influenza A commandeers human cells, including a surprising strategy that dissolves tiny structures in the nucleus and releases proteins the virus may use to reproduce. The detailed molecular map could reveal new...
A naturally occurring compound found in foods such as wheat germ, mushrooms, and aged cheese may help older adults build stronger protection after vaccination. In a small pilot trial, researchers gave spermidine supplements to adults...
An experimental drug called DT-109 reversed severe fatty liver disease in animal studies by repairing the gut and preventing harmful toxins from damaging the liver. The discovery could open the door to a new class of treatments for MASH...
A new study found that dietary fiber can determine whether beneficial intestinal worms help reduce inflammation or become essentially inactive. With plenty of fiber, the worms remained healthy and supported an anti-inflammatory response,...
Researchers found that mRNA cancer vaccines can recruit an unexpected immune cell to launch powerful tumor-fighting responses, overturning a long-held assumption about how the vaccines work. The discovery could lead to more effective...
Scientists have discovered that creatine may strengthen one of the immune system's most important cancer-fighting pathways by energizing dendritic cells that activate killer T cells. The promising results could eventually help make...
A new intranasal DNA vaccine may give the immune system an extra weapon against tuberculosis by targeting bacteria that can hide from antibiotics. In animal studies, it helped clear infections faster, reduced lung inflammation, and...
Scientists found that one tiny genetic change can completely alter how a coronavirus behaves in different species. Comparing SARS-CoV-2 with a closely related bat-only virus, they showed that a single amino-acid difference affects...
Scientists discovered that kombucha’s flavor, chemistry, and antioxidant activity vary dramatically depending on the tea used to make it. Green and oolong tea kombuchas emerged as the most biologically active, while fermentation...
Researchers uncovered why H5N1 bird flu attacks cows’ udders instead of their lungs: the virus’s preferred receptors are concentrated in mammary tissue. The breakthrough could help scientists predict future bird flu jumps and spot...
A low-calorie fasting-style diet significantly reduced inflammation linked to gum disease in a small clinical study. The findings suggest that what people eat may influence gum health almost as much as what they do with a toothbrush.
Tea may help protect against heart disease, diabetes, cancer, cognitive decline, and age related muscle loss, according to a major review. But the way you drink it matters, since bottled and bubble teas often contain ingredients that can...
Scientists have uncovered a hidden immune system "brake" that may help cancers avoid being destroyed. The molecule, called SLAMF6, weakens the body's cancer-fighting T cells and can leave them exhausted over time. Researchers developed...
A major long-term study of more than 54,000 adults found that where nitrate comes from may matter far more than how much you consume. People who got more nitrate from vegetables—roughly the amount in a cup of baby spinach a day—had a...
Scientists have successfully tested an AI-designed universal coronavirus vaccine in humans for the first time, finding it to be safe and well tolerated. The vaccine generated immune responses against multiple coronaviruses, including...
Scientists have uncovered a surprising new way the immune system fights cancer, overturning a core belief that has guided immunology for decades. The research found that when cancer cells shut down a key immune-recognition molecule...
A Salk Institute study found that a simple dietary amino acid, methionine, dramatically improved survival in mice facing severe infections and inflammatory conditions. Rather than directly targeting the immune system, methionine boosted...
Scientists at Scripps Research have uncovered a molecular “switch” that appears to fuel the damaging brain inflammation seen in Alzheimer’s disease. They found that a protein called STING becomes chemically altered in a way that keeps...
A new study suggests fish oil may help reduce insulin resistance even in people who aren't obese. In diabetic rats, omega-3 supplementation improved blood sugar levels, cholesterol, and inflammation by shifting immune cells into a more...