Getting older brings certain expectations, from gray hair and wrinkles to more bouts of forgetfulness. While these beliefs may seem harmless, whether a person views these changes in a positive or negative light may influence how they...
Prostate cancer is the second most common cancer in men, and almost 300,000 individuals are diagnosed with it each year in the U.S. To develop a consistent method of estimating prostate cancer size, which can help clinicians more...
The intersection of arts and neuroscience reveals transformative effects on health and learning, as discussed by Susan Magsamen in her neuroaesthetics research.
A leading scientist whose discoveries about prostate cancer led to lifesaving treatments is now shedding light on an emerging and deadlier form of the disease: neuroendocrine prostate cancer (NEPC).
Frequent internet use is linked to improved episodic memory, with daily users performing better in memory tasks than those who use it less often. The study suggests digital engagement may enhance cognitive abilities over time.
Dance programs improve older adults' physical and mental well-being, with ballroom and folk dance showing the most consistent benefits. More inclusive, theory-driven studies are needed to optimize outcomes.
A study found that anthocyanin-rich elderberry juice can improve gut microbiota, reduce blood glucose levels, and increase fat oxidation in overweight adults after just one week of consumption.
A five-year study on a low-carbohydrate, remote care intervention for type 2 diabetes shows significant improvements in diabetes remission, weight loss, and cardiometabolic health, reducing the need for medications.
Adhering to the Mediterranean diet reduces the risk of developing a second cardiometabolic disease, especially over shorter follow-up periods, with social class influencing the diet’s impact.
Black men with advanced prostate cancer have a greater chance of survival after immunotherapy treatment, at least in part, because of ancestral gene variants in immune responses.
A team tests the protective effect of a fermented black garlic extract against inflammation and the progression of prostate cancer in a study conducted on human prostate cancer cell models in the laboratory.
A blood test, performed when metastatic prostate cancer is first diagnosed, can predict which patients are likely to respond to treatment and survive the longest. It can help providers decide which patients should receive standard...
Researchers describe the mechanisms of how alterations in the CDK12 gene drive prostate cancer development and report on a promising degrader that targets CDK12 and a related gene to destroy tumors.
A new study sheds light on testosterone recovery following androgen deprivation therapy (ADT) in men undergoing radiotherapy for prostate cancer, providing key insights for optimizing patient care.
A new preclinical model using CRISPR, an advanced technology that allows scientists to cut and edit genes, has given researchers a deeper insight into how prostate cancer spreads or metastasizes.
There is a challenge related to prostate and many other cancers that cancer cells form resistance to treatments as the disease progresses. However, these resistance mechanisms are not yet fully understood. A new study found that...
A multi-institutional clinical trial showed that a newer technique for collecting prostate biopsy samples reduced the risk of infection compared with traditional biopsy approaches.
By tracking the changes in prostate cancer cells over time, researchers have found that activation of the MYC gene -- a well-known cancer-causing gene -- sets off a cascade of events that leads to both initiation and progression of the...
New research has shown that immunotherapy can be effective in treating prostate cancer in men who are selected based on the genetic characteristics of their tumors. In a recent study, it was found that for some men with a particular...
West African genetic ancestry was associated with increased prostate cancer among men living in disadvantaged neighborhoods but not among men living in more affluent neighborhoods, according to a new study. The findings suggest that...
Researchers have uncovered a key reason why a typically normal protein goes awry and fuels cancer. They found the protein NSD2 alters the function of the androgen receptor, an important regulator of normal prostate development. When...
A treatment paradox has recently come to light in prostate cancer: blocking testosterone production halts tumor growth in early disease, while elevating the hormone can delay disease progression in patients whose disease has advanced....
Compounds containing astatine-211 (211At) can be used in targeted radiotherapies for prostate cancer, but deastatination in the body remains a significant hurdle. Now, researchers have developed a new molecule with a neopentyl glycol...
The anti-cancer drug olaparib may be effective in treating biochemically recurrent prostate cancer without accompanying hormone therapy for men who have mutations in genes such as BRCA2, according to results of a phase II clinical trial...
Men with metastatic castration-resistant prostate cancer should be treated primarily with second-generation hormone drugs, which offer better treatment response and longer life expectancy than chemotherapy. However, the effect depends on...
The Stockholm3 blood test is equally effective at detecting prostate cancer in different ethnic groups, a new paper reports. The test produces significantly better results than the current PSA standard.
A recent study examined data from more than 10,000 patients with 'Biopsy Gleason Grade Group (GGG) 1,' a diagnosis considered to be the lowest grade cancer. Researchers found that even among patients diagnosed using the most modern...
Transgender women are still at risk for prostate cancer. A new study concludes that current screening guidelines could miss early-stage prostate cancer in transgender women on hormone therapy.
AI detects prostate cancer more often than radiologists. Additionally, AI triggers false alarms half as often. This was a large-scale study where an international team transparently evaluated and compared AI with radiologist assessments...
By using AI to assist with cancer contouring, the researchers found predicting the cancer size was 45 times more accurate and consistent than when physicians used only conventional clinical imaging and blood tests to predict the cancer...
As prostate cancer progresses, it becomes increasingly aggressive and can metastasize. In this form, the tumor is difficult to treat, which is reflected in high mortality rates: Worldwide, the malignant disease of the prostate is the...
A recent study suggests that the SIX2 protein may be a possible factor underlying increased plasticity of prostate cancer cells and treatment resistance.
Men with prostate cancer could significantly reduce the chances of the disease worsening by eating more fruits, vegetables, nuts, and olive oil, according to new research.
Adding a pre-ketone supplement -- a component of a high-fat, low-carb ketogenic diet -- to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers found.
New research sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.
A large randomized trial shows that a new three-step prostate cancer screening method can find a considerable number of aggressive cancers. Population-level screening programs have not been launched in most countries.
The drug finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering...
Sandalwood oil has been used worldwide for centuries. Now, a study is the first to demonstrate in vivo the chemo-preventive properties of a by-product of the oil in a mouse model. Results show administering alpha-santalol reduced visible...
Combining testosterone-blocking drugs in patients with prostate cancer relapse prevents the spread of cancer better than treatment with a single drug, a multi-institution, Phase 3 clinical trial has found.
A 10-year follow up study of nearly 2,500 U.S. men who received prostate cancer treatment will help inform decision making in terms of treatments and side effects for a diverse population.
Researchers have identified a receptor protein known as CHRM1 as a key player in prostate cancer cells' resistance to docetaxel, a commonly used chemotherapy drug to treat advanced cancer that has spread beyond the prostate. The study...
Researchers have developed a blood test that can reliably detect neuroendocrine prostate cancer and differentiate it from castration-resistant prostate cancer-adenocarcinoma (CRPC-adeno).
More than 65,000 men fall ill with prostate cancer each year in Germany. Twelve thousand of them develop a treatment-resistant form which eventually ends in death. Now, a team of researchers has developed an active substance that might...
A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk -- 451 in all -- through a whole-genome analysis that ranks as the largest and most diverse investigation...
Studies exploring metformin's power to prevent prostate cancer progression have been inconclusive. Research now shows that the drug has promise, but only for specific patients.
Investigators have identified two promising new treatment options for men with recurrent prostate cancer -- both of which helped patients live longer without their disease progressing than the current standard treatment. 'If these...
Using MRI as a screening test alongside PSA density allowed detection of cancers that would have been missed by the blood test alone, according to new research.