Scientists have uncovered a surprising sugar-related mechanism inside brain cells that could transform how we fight Alzheimer’s and other dementias. It turns out neurons don’t just store sugar for fuel—they reroute it to power...
Deleting a gene called PTEN in certain brain cells disrupts the brain’s fear circuitry and triggers anxiety-like behavior in mice — key traits seen in autism. Researchers mapped how this genetic tweak throws off the brain's delicate...
Misbehaving T cells light up long before Parkinson’s symptoms show, zeroing in on vulnerable brain proteins. Their early surge could double as an alarm bell and a target for stop-it-early treatments.
A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration with...
Groundbreaking research by the University of Sydney has identified a new brain protein involved in the development of Parkinson's disease and a way to modify it, paving the way for future treatments for the disease.
Parse Biosciences today announced their commitment to support researchers from the Icahn School of Medicine at Mount Sinai in generating one of the largest single cell datasets focused on understanding alternative splicing events in the...
Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.
Washington University researchers found that raising a molecule called ApoM helps eye cells sweep away harmful cholesterol deposits linked to age-related macular degeneration, potentially preventing vision loss, and the same trick might...
Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.
A newly developed PET radiotracer has shown the ability to produce high-quality images of real-time brain inflammation, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.
Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered...
Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis.
Researchers in East London found that South Asian and Black Parkinson’s disease patients experience more severe motor and cognitive symptoms than White patients. Despite similar access to diagnosis, disparities persist, highlighting the...
Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. Current tests,...
Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not only slowed...
Sleep apnea will become more common and more severe due to global warming, leading to increased health and economic burdens across the globe, warn Flinders University sleep experts.
A team at the University of California, Los Angeles has developed a low-cost diagnostic pen that converts handwriting into electrical signals for early detection of Parkinson's disease, achieving 96.22% accuracy in a pilot study.
UC Irvine researchers conducted a study to better understand the molecular basis of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder in which patients lose the ability to move, becoming weak and wheelchair bound before...
The asthma medication theophylline is a suitable drug for treating the rare neurological disorder ADCY5-related dyskinesia, according to a new study by Martin Luther University Halle-Wittenberg (MLU), which was published in the journal...
At the Center for Advanced Research in Sleep Medicine (CARSM), at Montreal's Sacré-Coeur Hospital, Université de Montréal medical professor Shady Rahayel sees many patients with RBD.
Parkinson's disease is best known for its effects on the central nervous system. In addition, recent scientific advances generally emphasize the role of the immune system in the presence and development of the disease.
Considered the natural "hunger hormone," ghrelin could be the key to preventing debilitating chronic constipation experienced by people living with Parkinson's disease, University of Queensland researchers have found.
Neurons deep in the brain not only help to initiate movement -- they also actively suppress it, and with astonishing precision. The findings are especially relevant for better understanding neurological disorders such as Parkinson's...
Neurons deep in the brain not only help to initiate movement—they also actively suppress it, and with astonishing precision. This is the conclusion of a new study by researchers at the University of Basel and the Friedrich Miescher...
People with an autism diagnosis are at a higher risk of developing Parkinson's disease early in life, a large-scale study from Karolinska Institutet published in JAMA Neurology reports. The researchers believe that the two conditions can...
Persons with Parkinson's disease increasingly lose their mobility over time and are eventually unable to walk. Hope for these patients rests on deep brain stimulation, also known as a brain pacemaker.
Dr. Simrit Parmar, an associate professor in the College of Medicine at Texas A&M University and founder of the clinical-stage biotech company Cellenkos Inc. in Houston, has invented a new cell therapy that shows strong promise for the...
When Columbia neurologist and scientist Neil Shneider speaks to his ALS patients who volunteer for experimental therapies, he's unwaveringly honest. "Patients always ask me, 'What can I hope to get out of this?"' Shneider says. "And I...
For patients with amyotrophic lateral sclerosis (ALS), rapid eye movement (REM) inhibition via receipt of antidepressant medication is associated with a trend toward survival benefit, according to a study presented at the American...
During REM sleep, the body enters a state of paralysis. This can pose a danger for patients with weakened diaphragms due to neuromuscular diseases. Now new research published at the ATS 2025 International Conference has shown that...
Using the gene scissors CRISPR and stem cells, researchers at Stockholm University and the UK Dementia Research Institute (UK DRI) at King's College London have managed to identify a common denominator for different gene mutations that...
Impaired neuromusculoskeletal function due to conditions such as stroke, osteoarthritis, cerebral palsy, Parkinson's disease, limb amputation, spinal cord injury, traumatic brain injury and cancer is a leading cause of disability and...
Huntington's disease is a genetic disorder that kills nerve cells in the brain, causing people to lose their cognitive and motor abilities. New research led by Thomas Jefferson University researcher Anna Pluciennik, Ph.D. is revealing...
To help neurologists, clinicians and families understand the current evidence for a new gene therapy for Duchenne muscular dystrophy called delandistrogene moxeparvovec, the American Academy of Neurology (AAN) has issued an Evidence in...
For millions of people around the world with essential tremor, everyday activities from eating and drinking to dressing and doing basic tasks can become impossible. This common neurological movement disorder causes uncontrollable...
The results of the MIROCALS randomized clinical trial have shown that adding low-dose interleukin-2 (IL2LD) to standard treatment for amyotrophic lateral sclerosis slowed functional decline and extended the lifespan of people with this...
A team of researchers has made a discovery in fruit flies that could change the way we understand brain diseases like Alzheimer's and Parkinson's in humans. The scientists found that Eato -- a fruit-fly protein whose counterparts in...
A groundbreaking open-source computer program uses artificial intelligence to analyze videos of patients with Parkinson's disease and other movement disorders. The tool, called VisionMD, helps doctors more accurately monitor subtle motor...
Scientists have developed a biorobotic arm that can mirror human tremors, such as those experienced by individuals that live with Parkinson's disease. Artificial muscles on either side of the forearm contract and relax to suppress the...
Key cells in the brain, neurons, form networks by exchanging signals, enabling the brain to learn and adapt at incredible speed. Researchers have now developed a 3D-printed 'brain-like environment' where neurons grow similarly to a real...
Researchers have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that can potentially be repurposed for PD...
The standard medication levodopa does not always work against tremors in Parkinson's disease, especially in stressful situations. Propranolol, however, does work during stress, providing insight into the role of the stress system in...
A recently published study found that a tiny protein called PNA5 appears to have a protective effect on brain cells, which could lead to treatments for the cognitive symptoms of Parkinson's disease and related disorders.
TFW when you're so excited you get those butterflies in your stomach - or maybe when you see something icky, you feel ill. On today's show, producer Berly McCoy looks at this relationship between our gut and our brain. Berly talks to...