Parkinson's doesn't just affect movement and the brain - it may also impact the heart, according to new research from the University of Surrey. Scientists from Surrey's School of Veterinary Medicine suggest that targeting a key protein...
Parkinson's doesn't just affect movement and the brain -- it may also impact the heart, according to new research. Scientists suggest that targeting a key protein outside of the brain could help manage Parkinson's-related heart issues.
Parkinson's doesn't just affect movement and the brain—it may also impact the heart, according to new research from the University of Surrey. Scientists from Surrey's School of Veterinary Medicine suggest that targeting a key protein...
A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of...
A novel PET imaging approach can effectively quantify a key enzyme associated with brain inflammation, according to research published in the March issue of The Journal of Nuclear Medicine.
For the first time, scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility, according to new research published in the March issue of The Journal of Nuclear Medicine.
Scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility. PET imaging shows that the brain increases dopamine production when completing cognitively demanding tasks, and that the more dopamine...
After a twitching pinky finger led to a diagnosis of young-onset Parkinson's disease, Keith Krehbiel, then 42, stopped at a bookstore on the way home to learn more about the progressive neurological disorder before telling his wife Amy...
Researchers at Indiana University and Wuhan University in China have unveiled a groundbreaking chemical process that could streamline the development of pharmaceutical compounds, chemical building blocks that influence how drugs interact...
As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease, among others.
In an international research collaboration involving the University Medical Center Göttingen (UMG), researchers have produced the most complete map to date of how long different proteins persist in many tissues of the body. They were...
A team that includes a RIKEN researcher has refined a lab test for measuring protein aggregate levels in samples from patients with certain neurodegenerative diseases. This has the potential to improve diagnosis and drug development for...
University of Florida researchers have led a multicenter study demonstrating that Automated Imaging Differentiation for Parkinsonism (AIDP), a machine-learning method using magnetic resonance imaging (MRI), accurately distinguishes...
Getting a headache and feeling sick are common side-effects for many medicines. Indulging in risky sexual behavior or pathological gambling—not so common.
WEHI researchers have made a huge leap forward in the fight against Parkinson's disease, solving a decades-long mystery that paves the way for development of new drugs to treat the condition.
Researchers have made a huge leap forward in the fight against Parkinson's disease, solving a decades-long mystery. In a major breakthrough, they have been able to see the human PINK1 protein and how it is switched on for the first time....
Mild cognitive impairment (MCI) can be an early indicator of Alzheimer's disease or dementia, so identifying those with cognitive issues early could lead to interventions and better outcomes.
WEHI researchers have made a huge leap forward in the fight against Parkinson's disease, solving a decades-long mystery that paves the way for the development of new drugs to treat the condition.
For people with a certain sleep disorder, a simple blood test could help predict the development of dementia years before symptoms appear, a new study indicates. Idiopathic REM sleep behavior disorder (iRBD) causes people to physically...
The herb rosemary has long been linked with memory: "There's rosemary, that's for remembrance," says Ophelia in Shakespeare's Hamlet. So it is fitting that researchers would study a compound found in rosemary and sage-carnosic acid-for...
A recently launched Phase 1 clinical trial is examining the safety and feasibility of a groundbreaking treatment approach for Parkinson's disease in which a patient's stem cells are reprogrammed to replace dopamine cells in the brain....
A new study published in Cell Reports reveals a breakthrough discovery linking genetic variants in the gene ITSN1 to a significantly elevated risk of Parkinson's disease, a neurodegenerative condition that affects nearly 2% of adults...
Scientists have developed a biorobotic arm that can mirror human tremors, such as those experienced by individuals that live with Parkinson's disease. Artificial muscles on either side of the forearm contract and relax to suppress the...
By 2050, there will be 25.2 million people living with Parkinson's disease worldwide (a 112% increase from 2021), largely due to population aging, suggests a modeling study published by The BMJ.
Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's disease, according to a study published in Nature Communications.
People with obstructive sleep apnea have an increased risk of Parkinson's disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study presented at the American...
ALS, or amyotrophic lateral sclerosis, can sometimes be difficult to diagnose or to predict how quickly the disease is likely to progress. A new study helps determine which blood tests are best at identifying and monitoring ALS. The...
The new research reveals how a protein in brain cells may drive Parkinson's onset -- and offers a possible explanation for why Parkinson's is much more common in men.
Scientists at La Jolla Institute for Immunology (LJI) have found a potential new target for treating Parkinson's disease. Their new research reveals how a protein in brain cells may drive Parkinson's onset—and offers a possible...
A form of Parkinson's disease caused by mutations in a gene known as PINK1 has long been labeled rare. But our research shows it's anything but—at least for some populations.
Massachusetts General Hospital coordinated the first four platform trials within the HEALEY ALS platform to evaluate potential treatments for amyotrophic lateral sclerosis (ALS), with results published in various JAMA journals.
Researchers have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. The study shows that this metabolite is responsible for the formation of Lewy bodies and the death of...
Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. Published in the journal PLOS Biology, the study shows...
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle weakness and eventually death. While significant strides have been made in...
In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells. The process of proteins spontaneously clumping is called protein aggregation and researchers...
From a study that analyzed brain images of more than 2,500 people with Parkinson's disease in 20 different countries, scientists have been able to identify patterns of neurodegeneration and create metrics for each of the five clinical...
Fingernail-sized vibrating gadgets, similar to the tiny devices that make your cellphone buzz, could help people with Parkinson's disease navigate the world with more confidence and ease. The vibrating devices, which may also help people...
A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream...
The U.S. Food and Drug Administration has approved Onapgo (apomorphine hydrochloride) injection as the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in patients with advanced Parkinson...
The GLP-1 drug, exenatide, has no positive impact on the movement, symptoms or brain imaging of people with Parkinson's, finds a new study led by UCL researchers.
Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the protein α-synuclein in nerve cells. When misfolded, this protein can produce clumps known as Lewy bodies, which...
A compound that showed early promise in the treatment of Parkinson's disease in fruit flies has also shown neuroprotective effects in mice, according to researchers at The University of Alabama.
The U.S. will ban nearly all uses of the common industrial cleaning agent, trichloroethylene (TCE), this year—more than 50 years after it led to one of the country's worst cases of contaminated drinking water. It has been found in up to...
Key cells in the brain, neurons, form networks by exchanging signals, enabling the brain to learn and adapt at incredible speed. Researchers have now developed a 3D-printed 'brain-like environment' where neurons grow similarly to a real...
Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that...
A Colorado Springs family hopes to win what they believe would be a landmark legal verdict by proving to jurors next month that mold exposure in a rented apartment caused Parkinson's disease in a former head of several Olympic sports...