By 2050, there will be 25.2 million people living with Parkinson's disease worldwide (a 112% increase from 2021), largely due to population ageing, suggests a modelling study published by The BMJ today.
By 2050, there will be 25.2 million people living with Parkinson's disease worldwide (a 112% increase from 2021), largely due to population aging, suggests a modeling study published by The BMJ.
This recently published exploration into the subventricular zone (SVZ) highlights its critical role in neural regeneration, neurodegenerative diseases, and glioblastoma multiforme (GBM).
Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's disease, according to a study published in Nature Communications.
A decade after scientists in The Picower Institute for Learning and Memory at MIT first began testing whether sensory stimulation of the brain's 40Hz "gamma" frequency rhythms could treat Alzheimer's disease in mice, a growing evidence...
For the one million people diagnosed with Parkinson's disease in the United States, Medtronic plc (NYSE:MDT), a global leader in healthcare technology, proudly announces U.S. Food and Drug Administration (FDA) approval of BrainSense™...
People with obstructive sleep apnea have an increased risk of Parkinson's disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study released today, March 2,...
This recent study highlights the neuroprotective potential of TFE3, a transcription factor that plays a pivotal role in counteracting key pathological mechanisms associated with Parkinson's disease (PD).
People with obstructive sleep apnea have an increased risk of Parkinson's disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study presented at the American...
ALS, or amyotrophic lateral sclerosis, can sometimes be difficult to diagnose or to predict how quickly the disease is likely to progress. A new study helps determine which blood tests are best at identifying and monitoring ALS. The...
The new research reveals how a protein in brain cells may drive Parkinson's onset -- and offers a possible explanation for why Parkinson's is much more common in men.
Higher coffee consumption is causally linked to delayed onset of Parkinson’s disease but does not affect disease risk or progression, according to a Mendelian randomization study.
Scientists at La Jolla Institute for Immunology (LJI) have found a potential new target for treating Parkinson's disease. Their new research reveals how a protein in brain cells may drive Parkinson's onset—and offers a possible...
A form of Parkinson's disease caused by mutations in a gene known as PINK1 has long been labeled rare. But our research shows it's anything but—at least for some populations.
Starting today, people with Parkinson's disease will have a new treatment option, thanks to U.S. Food and Drug Administration approval of groundbreaking new technology.
Massachusetts General Hospital coordinated the first four platform trials within the HEALEY ALS platform to evaluate potential treatments for amyotrophic lateral sclerosis (ALS), with results published in various JAMA journals.
Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. Published in the journal PLOS Biology, the study shows...
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle weakness and eventually death. While significant strides have been made in...
In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells. The process of proteins spontaneously clumping is called protein aggregation and researchers...
From a study that analyzed brain images of more than 2,500 people with Parkinson's disease in 20 different countries, scientists have been able to identify patterns of neurodegeneration and create metrics for each of the five clinical...
Fingernail-sized vibrating gadgets, similar to the tiny devices that make your cellphone buzz, could help people with Parkinson's disease navigate the world with more confidence and ease. The vibrating devices, which may also help people...
A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream...
The U.S. Food and Drug Administration has approved Onapgo (apomorphine hydrochloride) injection as the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in patients with advanced Parkinson...
The GLP-1 drug, exenatide, has no positive impact on the movement, symptoms or brain imaging of people with Parkinson's, finds a new study led by UCL researchers.
Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the protein α-synuclein in nerve cells. When misfolded, this protein can produce clumps known as Lewy bodies, which...
A compound that showed early promise in the treatment of Parkinson's disease in fruit flies has also shown neuroprotective effects in mice, according to researchers at The University of Alabama.
The U.S. will ban nearly all uses of the common industrial cleaning agent, trichloroethylene (TCE), this year—more than 50 years after it led to one of the country's worst cases of contaminated drinking water. It has been found in up to...
Key cells in the brain, neurons, form networks by exchanging signals, enabling the brain to learn and adapt at incredible speed. Researchers have now developed a 3D-printed 'brain-like environment' where neurons grow similarly to a real...
Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that...
A Colorado Springs family hopes to win what they believe would be a landmark legal verdict by proving to jurors next month that mold exposure in a rented apartment caused Parkinson's disease in a former head of several Olympic sports...
Researchers have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that can potentially be repurposed for PD...
The B vitamin mitigates manganese neurotoxicity, which produces symptoms that resemble Parkinson's disease. The vitamin improves dopamine production in the brain and offers potential therapeutic benefits.
While manganese is an essential mineral involved in many bodily functions, both deficiency and excessive exposure can cause health issues. Maintaining a balanced diet typically provides sufficient manganese for most individuals; however,...
Researchers find that microglia function differently in males versus females, potentially having broad implications for how neurological diseases are studied.
Yulan Xiong, associate professor of neuroscience at UConn Health, and her team have discovered one more piece of the puzzle of the genetic causes of Parkinson's Disease, paving the way for new treatment options.
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately 20 years before a clinical motor diagnosis in people with Huntington's disease, finds a study led by UCL researchers.
Delray Medical Center cut the ribbon on its newest high-tech machine last week that targets brain areas to treat movement disorders such as essential tremor and tremor-dominant Parkinson's disease.
There may be a link between hearing impairment and an increased risk of developing Parkinson's according to new research. This is one of the first studies to examine whether sensory impairments, such as hearing loss, might increase the...
A new discovery in blood immune cells has put researchers one step closer to identifying a blood biomarker that would allow doctors to personalize treatments for Parkinson's disease.
Older people wait an average of just over a month to see a neurologist for specialty care after being referred by their primary care physician or another physician, according to a new study. The study, which looked at people who have...
University of Bergen researcher Markus Miettinen is among the first scientists to provide a detailed description of protein clumps associated with Huntington's disease. The findings, which could pave the way for new diagnostic tools and...
Investigators have developed a novel approach that can better identify and characterize genetic variant interactions associated with increased risk of Parkinson's disease, improving the understanding of the genetic heritability of the...
The standard medication levodopa does not always work against tremors in Parkinson's disease, especially in stressful situations. Propranolol, however, does work during stress, providing insight into the role of the stress system in...