nutrition_enterale

Trends in eating disorder admissions to an acute NHS hospital: A retrospective review

Sat, 09 Aug 2025 08:24:53 +0000

Author Names: Jafar W.,Miller B.,Gosling A.,Goryl B.,Everton A.,Kerfoot S.,Morgan J.

Database Source: Embase Weekly Updates

Journal Title: Frontline Gastroenterology

Article Title: Trends in eating disorder admissions to an acute NHS hospital: A retrospective review

Year: 2025

Issue:

Volume:

Abstract: Objective: A retrospective review of clinical characteristics, admission patterns, management and discharge destinations of patients admitted with eating disorders (ED) to a UK hospital. Design/method: We conducted a retrospective review of electronic records and nutrition support team (NST) data for patients coded with an ED between January 2014 and December 2022. <br/>Result(s): During the study period, there were 81 admissions which represented 37 patients as some were admitted multiple times. Of the 81 admissions, 78 were females and the median age was 30 years. The highest spike of admissions (16) was seen at the peak of the pandemic with a steady increase prior to this. The underlying ED was primarily anorexia nervosa-restrictive subtype (73%). The majority of referrals were received from general practice (59.3%). Low body weight (46.9%) was the most common indication for admission. Median body mass index was 14.2 (range 10.2-22.7 kg/m2). Median time to receive a review was 4 days for NST, 2 days for dietetics and 10 days for the consultant psychiatrist. Nutrition was delivered via the oral route in 53.1% and nasogastric feeding tube in 46.9%. In 19.7%, nutrition was delivered under section of the Mental Health Act. Median length of stay was 9 days. Discharge destination included a specialist EDs unit for 21%, home with community follow-up in 38.3%, home with no follow-up in 29.6%. Two patients died during the study period. <br/>Conclusion(s): This study provides evidence of admission characteristics, review patterns and discharge destinations for patients admitted with ED. This study suggests an increase in ED admissions. NST involvement is highly recommended.<br/>Copyright © Author(s) (or their employer(s)) 2025.

Nutrition management of the postoperative lung transplant recipient.

Fri, 01 Aug 2025 04:00:00 +0000

Nutrition in Clinical Practice; 08/01/2025
(AN 186527112); ISSN: 08845336
CINAHL Complete

Nutrition management of a patient following emergent pneumonectomy due to chest wall trauma.

Fri, 01 Aug 2025 04:00:00 +0000

Nutrition in Clinical Practice; 08/01/2025
(AN 186527101); ISSN: 08845336
CINAHL Complete

Effects of early versus late enteral nutrition on the nutritional status of surgical intensive care unit patients: A retrospective observational study

Wed, 30 Jul 2025 00:00:00 +0000

Asia Pac J Clin Nutr. 2025 Aug;34(4):610-618. doi: 10.6133/apjcn.202508_34(4).0012.

ABSTRACT

BACKGROUND AND OBJECTIVES: We retrospectively evaluated the efficacy and safety of early enteral nutrition (within 48 h) and late enteral nutrition (after 48 h; control) in improving the nutritional status of surgical intensive care unit patients.

METHODS AND STUDY DESIGN: This single-center, retrospective, observational study was conducted using data from 82 patients (age > 18 years) who were admitted to surgical intensive care units between June and November 2019. Patients who received enteral nutrition for >7 days were included in this study, and those who received total parenteral nutrition or palliative care were excluded.

RESULTS: The early and late enteral nutrition groups comprised 41 patients each. Early enteral nutrition significantly increased the actual intake of calories and protein (p < 0.0001) as well as the length of stay in the surgical in-tensive care unit (p = 0.047) and hospital (p = 0.028). Late enteral nutrition significantly reduced albumin concentration (p < 0.05), hemoglobin concentration (p < 0.05), and lymphocyte count (p < 0.05) but significantly increased weight loss (p < 0.05). However, no significant between-group difference was observed in mortality rate.

CONCLUSIONS: Early enteral nutrition improves the nutritional status of surgical intensive care unit patients. It shortens overall hospitalization duration and increases actual calorie and protein intake at dis-charge. Thus, early enteral nutrition is recommended for critically ill patients.

PMID:40738728 | DOI:10.6133/apjcn.202508_34(4).0012

The Neurological Metabolic Phenotype in Prolonged/Chronic Critical Illness: Propensity Score Matched Analysis of Nutrition and Outcomes

Wed, 30 Jul 2025 00:00:00 +0000

Nutrients. 2025 Jul 12;17(14):2302. doi: 10.3390/nu17142302.

ABSTRACT

Background: Brain injuries, including stroke and traumatic brain injury (TBI), pose a major healthcare challenge due to their severe consequences and complex recovery. While ischemic strokes are more common, hemorrhagic strokes have a worse prognosis. TBI often affects young adults and leads to long-term disability. A critical concern in these patients is the frequent development of chronic critical illness, compounded by metabolic disturbances and malnutrition that hinder recovery. Objective: This study aimed to compare changes in nutritional status parameters under standard enteral nutrition protocols and clinical outcomes in prolonged/chronic critically ill patients with TBI or stroke versus such a population of patients without TBI or stroke. Methods: This matched prospective-retrospective cohort study included intensive care unit (ICU) patients with TBI or stroke from the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology and patients without these conditions from the eICU-CRD database. Inclusion criteria comprised age 18-74 years, ICU stay >5 days, and enteral nutrition. Patients with re-hospitalization, diabetes, acute organ failure, or incomplete data were excluded. Laboratory values and clinical outcomes were compared between the two groups. Propensity score matching (PSM) was used to balance baseline characteristics (age, sex, and body mass index). Results: After PSM, 29 patients with TBI or stroke and 121 without were included. Univariate analysis showed significant differences in 21 laboratory parameters and three hospitalization outcomes. On day 1, the TBI/stroke group had higher hemoglobin, hematocrit, lymphocytes, total protein, and albumin, but lower blood urea nitrogen (BUN), creatinine, and glucose. By day 20, they had statistically significantly lower calcium, BUN, creatinine, and glucose. This group also showed less change in lymphocytes, calcium, and direct bilirubin. Hospitalization outcomes showed longer mechanical ventilation duration (p = 0.030) and fewer cases of acute kidney injury (p = 0.0220) in the TBI/stroke group. Conclusions: TBI and stroke patients exhibit unique metabolic patterns during prolonged/chronic critical illness, differing significantly from other ICU populations in protein/glucose metabolism and complication rates. These findings underscore the necessity for specialized nutritional strategies in neurocritical care and warrant further investigation into targeted metabolic interventions.

PMID:40732927 | PMC:PMC12298954 | DOI:10.3390/nu17142302

The Neurological Metabolic Phenotype in Prolonged/Chronic Critical Illness: Propensity Score Matched Analysis of Nutrition and Outcomes.

Tue, 15 Jul 2025 04:00:00 +0000

Nutrients; 07/15/2025
(AN 186929880); ISSN: 20726643
CINAHL Complete

Phase II Protocol on the Safety and Nutritional Status of Postoperative Enteral Nutrition Using HINEX E-gel LC in Patients with Esophageal Cancer Undergoing Minimally Invasive Esophagectomy

Thu, 03 Jul 2025 00:00:00 +0000

Kobe J Med Sci. 2025 May 30;71(2):E50-E55. doi: 10.24546/0100495984.

ABSTRACT

BACKGROUND: Enteral nutrition therapy in the early postoperative period is essential for patients with esophageal cancer following esophagectomy. HINEX® E-gel LC is an oligomeric formula with various nutrients, including dietary fiber pectin. It is expected to reduce symptoms, such as diarrhea, resulting in improved adherence and a decreased rate of weight loss. However, no reports have examined the adherence to or efficacy of nutritional support therapy using HINEX® E-gel LC after esophagectomy.

METHODS: This is a single-institution, single-arm phase II trial. We plan to recruit 32 patients with esophageal cancer who have undergone minimally invasive esophagectomy (MIE) and place an enteral feeding tube. Enteral feeding is to be initiated on the second postoperative day, and the patient is to remain on enteral feeding at 300 kcal/day after discharge. The primary endpoint is adherence to enteral nutrition with HINEX® E-gel LC for up to 2 months postoperatively. The secondary endpoint is the association between the adherence to HINEX® E-gel LC and each nutritional parameter, such as hematological examination, body weight, and psoas muscle.

DISCUSSION: Although enteral nutrition is usually initiated in the early postoperative period after esophagectomy, the use of fat-containing digestive agents in the early postoperative period is a novel approach. To the best of our knowledge, this study is the first to evaluate the safety and nutritional status of early postoperative enteral nutrition using fat-containing digestive agents after MIE. Efficient nutritional support therapy using fat-containing digestive agents is expected to be especially useful after esophagectomy when oral intake is significantly decreased.

PMID:40610016 | DOI:10.24546/0100495984

Treatment adherence and nasogastric tube use in hospitalized youth with anorexia nervosa and premorbid overweight/obesity.

Tue, 01 Jul 2025 04:00:00 +0000

Eating Disorders; 07/01/2025
(AN 186283837); ISSN: 10640266
CINAHL Complete

Food and nutrition insecurity and clinical and anthropometric indicators in individuals with cancer eligible for radiotherapy.

Tue, 01 Jul 2025 04:00:00 +0000

European Journal of Clinical Nutrition; 07/01/2025
(AN 186781713); ISSN: 09543007
CINAHL Complete

Innovations in Pancreatic Enzyme Replacement Therapy for Enterally Fed Patients With Pancreatic Cancer.

Tue, 01 Jul 2025 04:00:00 +0000

Gastroenterology Nursing; 07/01/2025
(AN 186999080); ISSN: 1042895X
CINAHL Complete

Daily assessment of oral mucositis during volumetric modulated arc therapy planning technique for head and neck cancer: risk factors and impact on nutritional status

Mon, 30 Jun 2025 00:00:00 +0000

Support Care Cancer. 2025 Jul 1;33(7):644. doi: 10.1007/s00520-025-09671-8.

ABSTRACT

PURPOSE: To examine the occurrence, timing, and radiation dose associated with oral mucositis (OM) and body weight change in patients who underwent head and neck radiotherapy (RT) using the Volumetric Modulated Arc Therapy (VMAT) technique. It was also investigated whether these side effects affected nutritional status.

METHODS: Data regarding age, gender, tumor type, radiation doses, OM, weight loss, diet, and prescriptions for nasoenteral tubes and gastrostomy were collected retrospectively from 84 medical records of a single head and neck VMAT service.

RESULTS: Severe OM was observed in 61.8% of patients, occurring at a median cumulative dose of 37.7 Gy. Severe OM was significantly associated with radiation doses to the oral cavity and with concurrent chemotherapy, the latter being identified as a predictive factor. A median body weight loss of 6.1 kg was found in the majority of patients. Severe OM was linked with weight loss and the need for artificial nutrition.

CONCLUSION: The frequency of OM in the oral cavity was high in patients treated with VMAT, significantly impacting nutritional status. Radiation dose to the oral mucosa and concurrent chemotherapy were associated with severe OM.

PMID:40588605 | DOI:10.1007/s00520-025-09671-8

Analysis of nutritional status before and after different induction therapies in children with Crohn's disease

Mon, 30 Jun 2025 00:00:00 +0000

Zhongguo Dang Dai Er Ke Za Zhi. 2025 Jun 15;27(6):702-708. doi: 10.7499/j.issn.1008-8830.2410125.

ABSTRACT

OBJECTIVES: To study the impact of different induction remission therapies on the nutritional status of children with Crohn's disease (CD).

METHODS: A retrospective analysis was conducted on the medical data of 188 children with CD who received induction remission therapy at the Children's Hospital, Zhejiang University School of Medicine from January 2013 to May 2023. The effects of three induction remission therapies-exclusive enteral nutrition (EEN), corticosteroids, and infliximab (IFX)-on height, weight, hemoglobin, and trace elements were compared.

RESULTS: After induction remission therapy, the weight-for-age Z scores and serum levels of hemoglobin and albumin in all three groups significantly increased (P<0.05), while the height-for-age Z scores showed no change (P>0.05). The levels of folic acid, 25-hydroxy vitamin D, serum iron, and total calcium increased, and serum copper levels decreased in the EEN and IFX groups (P<0.05). Vitamin B₁₂ levels improved in the EEN group (P<0.05).

CONCLUSIONS: EEN, corticosteroids, and IFX may effectively improve the weight-for-age Z scores and serum levels of hemoglobin and albumin in children with CD. EEN and IFX seem to be superior to corticosteroid therapy in improving 25-hydroxy vitamin D, folic acid, serum iron, and total calcium levels.

PMID:40583710 | PMC:PMC12234130 | DOI:10.7499/j.issn.1008-8830.2410125

Post-pyloric feeding improves the nutritional status of severe tetanus patients and reduces the incidence of feeding intolerance

Fri, 06 Jun 2025 00:00:00 +0000

Clin Nutr ESPEN. 2025 Aug;68:509-514. doi: 10.1016/j.clnesp.2025.05.047. Epub 2025 Jun 4.

ABSTRACT

BACKGROUND: Patients with severe tetanus exhibit clinical features such as trismus, tetanic spasms, and rigidity, primarily affecting muscle groups including masseter muscles, erector spinae muscles, abdominal muscles, and limb muscles. The main objective of this study is to investigate whether post-pyloric feeding can improve the nutritional level of patients and reduce the incidence of feeding intolerance during the treatment of severe tetanus.

METHODS: A convenience sampling method was used to select 122 patients with tetanus who met the inclusion criteria from January 2020 to November 2023, and divided into groups that received Nasogastric feeding (NGF, n = 36) and Nasointestinal feeding (NIF, n = 36). Basic information was collected, nutritional biochemical indicators and frequency of intolerance were analyzed.

RESULTS: By day 7 and 14, the NIF group exhibited significantly higher levels of Albumin (ALB), Total Protein (TP), Prealbumin (PA) and Retinol Binding Protein (RBP) compared to the NGF group. At the same time, the incidence of nutritional intolerance in the NIF group was significantly lower compared to the NGF group.

CONCLUSION: Post-pyloric feeding can improve the nutritional level of patients with severe tetanus and reduce the frequency of feeding intolerance (diarrhea, abdominal distension and vomiting).

PMID:40480462 | DOI:10.1016/j.clnesp.2025.05.047

Nutrition issues in adult hematopoietic cell transplantation: A narrative review of latest advances.