nutrition_parenterale

Nutrition issues in adult hematopoietic cell transplantation: A narrative review of latest advances.

Sun, 01 Jun 2025 04:00:00 +0000

Nutrition in Clinical Practice; 06/01/2025
(AN 184927380); ISSN: 08845336
CINAHL Complete

Chronic intestinal failure knowledge among a cohort of ASPEN registered dietitians: Response to a membership survey.

Sun, 01 Jun 2025 04:00:00 +0000

Nutrition in Clinical Practice; 06/01/2025
(AN 184927379); ISSN: 08845336
CINAHL Complete

Quality improvement for parenteral nutrition in hospital: Applying a gap analysis to an electronic health record to review parenteral nutrition processing.

Sun, 01 Jun 2025 04:00:00 +0000

Nutrition in Clinical Practice; 06/01/2025
(AN 184927366); ISSN: 08845336
CINAHL Complete

Complete shielding of multivitamins to reduce toxic peroxides in the parenteral nutrition (C‐SMART‐PN): A randomized controlled pilot study.

Sun, 01 Jun 2025 04:00:00 +0000

Nutrition in Clinical Practice; 06/01/2025
(AN 184927373); ISSN: 08845336
CINAHL Complete

Clinical outcomes in Crohn's disease patients with short bowel syndrome on home parenteral nutrition are comparable to those with short bowel syndrome from other etiologies.

Sun, 01 Jun 2025 04:00:00 +0000

Clinical Nutrition; 06/01/2025
(AN 185202025); ISSN: 02615614
CINAHL Complete

Neonatal Seizures and White Matter Injury in a Newborn.

Sun, 01 Jun 2025 04:00:00 +0000

Clinical Pediatrics; 06/01/2025
(AN 185157291); ISSN: 00099228
CINAHL Complete

Carnitine supplementation in progressive supranuclear palsy.

Sun, 01 Jun 2025 04:00:00 +0000

Nutrition in Clinical Practice; 06/01/2025
(AN 184927368); ISSN: 08845336
CINAHL Complete

Micronutrient Status in Patients with Short Bowel Syndrome Weaned off Parenteral Support

Wed, 21 May 2025 08:20:57 +0000

Author Names: Mattio N.,Juin C.,Lauverjat M.,Chambrier C.,Bergoin C.,Couronne T.

Database Source: Embase Daily Updates

Journal Title: Nutrients

Article Title: Micronutrient Status in Patients with Short Bowel Syndrome Weaned off Parenteral Support

Year: 2025

Issue: 9

Volume: 17

Abstract: Background/Objectives: In short bowel syndrome adults (SBS), about 50% of patients on parenteral support (PS) are weaned off. However, micronutrient deficiency prevalence has never been studied in weaned patients. We aimed to assess the prevalence of micronutrient depletions and potential risk factors, more than a year after PS weaning. Method(s): A retrospective study was conducted on our 161 weaned SBS patients between January 2011 and December 2021. Only 42 of them had an assessment of their plasma micronutrient status more than a year after PS weaning. Result(s): 40/42 patients had at least one micronutrient depletion, with an average of 4.0 +/- 1.9 depletions per patient. Depletions in vitamins D, E, selenium, copper, and zinc were the most frequent, present for >50% of patients. In 75% of cases, patients depleted in vitamin B12 and D were already supplemented. Long-term proton pump inhibitor (PPI) use and duration on PS was associated with >= three depletions (p = 0.02). A daily mean of the total energy infused per week > 20 kcal/kg/day at the time of weaning was associated with more depletions (5.8 +/- 1.6 vs. 3.7 +/- 1.7 depletions, p = 0.02). Other factors (digestive anatomy, particularly SBS type, or associated chronic disease) were not predictive of depletion. Conclusion(s): Nearly all patients with SBS have at least one micronutrient depletion after PS withdrawal. This study suggests that a long-term monitoring of micronutrients status is needed for SBS patients weaned off PS. A larger-scale study would be necessary to generalize these results. Copyright © 2025 by the authors.

Nutrition support practices in the intensive care unit of a tertiary hospital in Ghana

Wed, 21 May 2025 08:20:57 +0000

Author Names: Anku E.K.,Samad L.O.,Akafity G.,Amoo S.A.,Hill L.T.

Database Source: Embase Daily Updates

Journal Title: Southern African Journal of Critical Care

Article Title: Nutrition support practices in the intensive care unit of a tertiary hospital in Ghana

Year: 2024

Issue: 1

Volume: 40

Abstract: Background. Nutrition support is recognised as an important therapy for attenuating the catabolic effects of critical illnesses, including malnutrition prevention. However, variations in nutrition support practices make it difficult to achieve optimal outcomes in the intensive care unit (ICU). Objectives. To explore current nutrition support practices among healthcare professionals (doctors and nurses) in the ICU of a tertiary hospital in Ghana. Methods. Via a cross-sectional survey, the nutrition support practices and self-reported skills of 30 ICU healthcare professionals (23 nurses and 7 doctors) providing nutrition support were explored. Results are presented as themes with frequencies and proportions. Categorical data were analysed using Fisher's exact test. Statistical significance was set at p<0.05. Results. Most of the respondents were young and had limited ICU experience. Almost half of the respondents were unaware of or were not familiar with the content of an in-house feeding protocol for both enteral nutrition (EN) and parenteral nutrition support, despite a majority reporting the feeding protocol as the main source of nutrition support information. There was a general lack of standardisation of execution of most nutrition support practices, especially with the pattern of EN delivery, usual method of optimising EN, and gastric residual volume threshold used to guide practice. Most respondents self-reported being average/satisfactory in the management of nutrition support. Conclusion. The study revealed that healthcare professionals in our ICU had varying nutrition support practices and competencies. There is a need for standardised and practical feeding protocols in accessible formats, ongoing education, and training in nutrition support to improve nutrition support practices and competencies of healthcare professionals providing nutrition support in the ICU setting. Copyright © 2024 South African Medical Association. All rights reserved.

The Impact of a Prolonged Multivitamin Shortage on Home Parenteral Nutrition Patients: A Single-Center Retrospective Cohort Study with Case Reports of Wernicke's Encephalopathy

Wed, 14 May 2025 00:00:00 +0000

Nutrients. 2025 Apr 29;17(9):1500. doi: 10.3390/nu17091500.

ABSTRACT

Background/Objectives: Shortages in parenteral nutrition (PN) micronutrient components can lead to deficiencies in patients heavily relying on home PN (HPN) to meet nutritional requirements. Despite monitoring, this can cause severe and even life-threatening conditions if intravenous (IV) micronutrients are not available for a prolonged period. Methods: We conducted a retrospective study to evaluate the effect of an IV multivitamin shortage that occurred between December 2022 and July 2023. The study included patients at high risk for multivitamin deficiencies who received HPN for at least 5 days. Patients were classified into two groups: those compliant with instructions to take additional oral multivitamin supplements to compensate for the shortage and those who were not compliant. Monitoring included tracking symptoms and routine bloodwork, which measured certain vitamins, excluding thiamine. Results: A total of 25 HPN patients were identified. Among them, 56% (n = 14) were compliant with daily oral multivitamin supplementation. No significant differences in pre- and post-shortage bloodwork were observed, but there was a significant difference in bicarbonate changes between the compliant and non-compliant groups (0 (-0.9, 1) vs. -2 (-8, -1), p = 0.04, respectively). Approximately 68% of all patients reported new symptoms during the shortage, but no significant difference was observed between groups. Three patients known to have increased gastrointestinal losses (two compliant and one non-compliant) required hospitalization: two had Wernicke's encephalopathy reversed with thiamine infusion. Conclusions: When IV multivitamins are unavailable for an extended period, at-risk patients need to be closely monitored by the HPN team, particularly for compliance to oral supplementation and for symptoms of thiamine deficiency when blood level monitoring is not feasible.

PMID:40362808 | PMC:PMC12073724 | DOI:10.3390/nu17091500

Total Parenteral Nutrition in Advanced Cancer: Applying a Shared Mental Model.

Thu, 01 May 2025 04:00:00 +0000

Journal of Pain & Symptom Management; 05/01/2025
(AN 184389568); ISSN: 08853924
CINAHL Complete

Breastfeeding Measurement—What Does It Mean to "Wean?".

Thu, 01 May 2025 04:00:00 +0000

Journal of Human Lactation; 05/01/2025
(AN 184442764); ISSN: 08903344
CINAHL Complete

Single-staged Anterior versus Posterior Sagittal Anorectoplasty for Low Female Arms.

Thu, 01 May 2025 04:00:00 +0000

Journal of Indian Association of Pediatric Surgeons; 05/01/2025
(AN 184798354); ISSN: 09719261
CINAHL Complete

Parenteral Nutrition Compatibility.

Thu, 01 May 2025 04:00:00 +0000

Journal of Infusion Nursing; 05/01/2025
(AN 184974714); ISSN: 15331458
CINAHL Complete

Multiomics profiling and parenteral nutrition weaning in pediatric patients with intestinal failure: A longitudinal cohort study.

Thu, 01 May 2025 04:00:00 +0000

JPEN Journal of Parenteral & Enteral Nutrition; 05/01/2025
(AN 184969109); ISSN: 01486071
CINAHL Complete

Role of dietitians in optimizing medical nutrition therapy in cardiac surgery patients: A secondary analysis of an international multicenter observational study.

Thu, 01 May 2025 04:00:00 +0000

JPEN Journal of Parenteral & Enteral Nutrition; 05/01/2025
(AN 184969117); ISSN: 01486071
CINAHL Complete

Intestinal failure–associated liver disease in adult patients with chronic intestinal failure receiving home parenteral nutrition: A descriptive cohort study.

Thu, 01 May 2025 04:00:00 +0000

JPEN Journal of Parenteral & Enteral Nutrition; 05/01/2025
(AN 184969113); ISSN: 01486071
CINAHL Complete

Managing pregnancy with long‐term parenteral nutrition: A case report and review of the literature.

Thu, 01 May 2025 04:00:00 +0000

JPEN Journal of Parenteral & Enteral Nutrition; 05/01/2025
(AN 184969119); ISSN: 01486071
CINAHL Complete

Parenteral Formulation: Deciding When to Go Frozen or Freeze-Dried.

Thu, 01 May 2025 04:00:00 +0000

Pharmaceutical Technology; 05/01/2025
(AN 184803905); ISSN: 15432521
CINAHL Complete

Gastric Lactobezoar: A Rare Cause of Intestinal Obstruction in Neonates.

Thu, 01 May 2025 04:00:00 +0000

Journal of Indian Association of Pediatric Surgeons; 05/01/2025
(AN 184798367); ISSN: 09719261
CINAHL Complete

External Lymphatic Fistula After Radical Surgery for Colorectal Cancer: A Case Series.

Thu, 01 May 2025 04:00:00 +0000

Cancers; 05/01/2025
(AN 185133254); ISSN: 20726694
CINAHL Complete

Fetal Distress as a Determinant for Refeeding Syndrome in Preterm Neonates.

Thu, 01 May 2025 04:00:00 +0000

Nutrients; 05/01/2025
(AN 185133018); ISSN: 20726643
CINAHL Complete

The Impact of a Prolonged Multivitamin Shortage on Home Parenteral Nutrition Patients: A Single-Center Retrospective Cohort Study with Case Reports of Wernicke's Encephalopathy.

Thu, 01 May 2025 04:00:00 +0000

Nutrients; 05/01/2025
(AN 185133101); ISSN: 20726643
CINAHL Complete

Nutrition Provision in Pediatric Extracorporeal Membrane Oxygenation: Evidence, Challenges, and Clinical Considerations.

Thu, 01 May 2025 04:00:00 +0000

Nutrients; 05/01/2025
(AN 185133154); ISSN: 20726643
CINAHL Complete

Possible Factors Affecting Breast Milk Feeding Status Of Preterm Infants Monitored in the Neonatal Intensive Care Unit.

Thu, 01 May 2025 04:00:00 +0000

Turkish Archives of Pediatrics; 05/01/2025
(AN 184983217); ISSN: 27576256
CINAHL Complete

Clinical outcomes in Crohn's disease patients with short bowel syndrome on home parenteral nutrition are comparable to those with short bowel syndrome from other etiologies

Wed, 30 Apr 2025 00:00:00 +0000

Clin Nutr. 2025 Jun;49:149-156. doi: 10.1016/j.clnu.2025.04.015. Epub 2025 Apr 24.

ABSTRACT

BACKGROUND & AIMS: Patients with short bowel syndrome (SBS) and chronic intestinal failure require home parenteral nutrition (PN) support. The main cause of SBS remains Crohn's disease (CD), and complications in this cohort versus SBS from other etiologies remains to be determined. We therefore sought to investigate whether patients with SBS secondary to CD versus SBS secondary to other etiologies, have increased risk of complications and whether there is a difference in overall mortality between groups.

METHODS: This is a multicentre prospective cohort study using the Canadian Home Parenteral Nutrition (HPN) Registry. Two groups were compared: 1) SBS secondary to CD (SBS-CD) vs. 2) SBS- secondary to other etiologies (SBS-Other) (including trauma, surgical complication, vascular event, volvulus and malignancy). Clinical data for each patient included: number of hospitalizations, number of hospitalizations related to HPN and number of hospitalization days related to HPN, incidence of line sepsis per 1000 catheter days and mortality. Descriptive statistics are presented as median (interquartile range) for continuous variables and as frequency (percentage) for categorical variables as appropriate. Comparison between groups were performed using a 2-sample t-test,Poisson regression analysis or Wilcoxon rank sum test for continuous variables and Chi-square or Fisher exact tests when appropriate for categorical variables. Kaplan-Meir curve and multivariate analysis was performed to assess mortality. Statistical significance is set at a p-value <0.05.

RESULTS: The study included 383 patients with SBS and intestinal failure: 172 (45 %) SBS-CD and 211 (55 %) SBS-Other; followed for median of 4 (2, 6) years and 2 (2, 4) years respectively (p = 0.027). The groups were comparable at baseline except for younger age, shorter small bowel length and medications with higher use of immunosuppressant therapy (39 % vs. 7 %, p < 0.001) in those with CD. The number of hospitalizations, hospitalization days, and line sepsis per 1000 catheter days were similar amongst the SBS- CD and SBS-Other (p > 0.05 across all primary outcomes). Mortality events were also similar between groups (31 patients (26.72 %) in SBS CD group vs. 37 patients (29.84 %) in SBS- Other group, p = 0.6676). The Kaplan-Meir curve did not show a statistical difference in mortality between groups but a multivariate analysis of the entire patient population showed that age was associated with mortality. In subgroup analysis, patients with SBS- CD taking immunosuppressant therapy were not at higher risk of hospitalizations or line sepsis compared to those not on immunomodulating therapies (0.50 versus 1.57 p = 0.0417).

CONCLUSION: Individuals with SBS CD do not have increased risk of hospitalizations, central line infections or mortality compared to those with SBS from other causes. In CD, those on immunomodulating therapies do not appear to be at increased risk of complications.

PMID:40305998 | DOI:10.1016/j.clnu.2025.04.015

Reducing waste in parenteral nutrition: comparison of Surgical- and Standard-Aseptic Non-Touch Technique.

Thu, 17 Apr 2025 04:00:00 +0000

British Journal of Nursing; 04/17/2025
(AN 184604420); ISSN: 09660461
CINAHL Complete

Two Sides of a Discharge.

Mon, 14 Apr 2025 04:00:00 +0000

JAMA Network Open; 04/14/2025
(AN 184594333); ISSN: 25743805
CINAHL Complete

Nutrition risk stratification and metabolic disorders in patients on parenteral nutrition

Fri, 11 Apr 2025 00:00:00 +0000

Rev Esc Enferm USP. 2025 Apr 11;59:e20240274. doi: 10.1590/1980-220X-REEUSP-2024-0274en. eCollection 2025.

ABSTRACT

OBJECTIVE: To evaluate the association between metabolic disorders and death in patients receiving Parenteral Nutrition (PN), according to a proposal for stratification into nutri-tional risk groups, using the Nutritional Risk Screening, 2002 (NRS-2002).

METHOD: A cohort with 84 patients receiving PN, with an NRS-2002 score of ≥3, classified into two subgroups: moderate risk (NRS 3-4) and severe risk (NRS 5-7). Secondary data from medical and nutritional records were used. The outcome variable was "presence of metabolic disorders and death"; and exposures: moderate and severe nutritional risk. Descriptive, bivariate analyses and logistic regression models were performed.

RESULTS: No difference was observed between the groups in terms of death. The adjusted RR (95% CI) for sodium disorders was 4.88 (1.5-16.2) (p = 0.009), and for magnesium disorders, 7.58 (2.33-24.6) (p = 0.001), being higher in the severe risk group.

CONCLUSION: The stratification of the nutritional risk range into moderate and severe risk was able to identify patients at higher risk of developing metabolic disorders, especially sodium and magnesium ones.

PMID:40215353 | PMC:PMC11991668 | DOI:10.1590/1980-220X-REEUSP-2024-0274en

Managing pregnancy with long-term parenteral nutrition: A case report and review of the literature

Wed, 02 Apr 2025 00:00:00 +0000

JPEN J Parenter Enteral Nutr. 2025 May;49(4):528-533. doi: 10.1002/jpen.2758. Epub 2025 Apr 2.

ABSTRACT

Parenteral nutrition (PN) is essential for patients with chronic intestinal failure but poses significant challenges during pregnancy because of increased nutrition needs and associated risks such as central line-associated bloodstream infections. We report a case of a 29-year-old primigravid woman with Crohn's disease who required chronic PN. Despite these complexities, her pregnancy was managed successfully with tailored PN adjustments. She developed intrahepatic cholestasis of pregnancy at 38 weeks and delivered a healthy, full-term newborn. Meticulous planning and individualized nutrition management are crucial in navigating the complexities of PN during pregnancy, demonstrating the potential for successful outcomes with strategic and personalized interventions.

PMID:40170624 | PMC:PMC12053229 | DOI:10.1002/jpen.2758

Glucose Management in Hospitalized Adults Receiving Parenteral Nutrition: Strategies and Considerations.